Characterizing monoclonal antibody structure by carboxyl group footprinting

Submillisecond Protein Folding Events Monitored by Rapid Mixing and Mass Spectrometry-Based Oxidative Labeling

(2013) Siavash Vahidi et al.   ANALYTICAL CHEMISTRY

Structural analysis of a therapeutic monoclonal antibody dimer by hydroxyl radical footprinting

(2013) Galahad Deperalta et al.   mAbs

Conformational Analysis of Therapeutic Proteins by Hydroxyl Radical Protein Footprinting

(2012) Caroline Watson et al.   AAPS Journal

Analytical lessons learned from selected therapeutic protein drug comparability studies

(2012) Marcia Federici et al.   BIOLOGICALS

Disulfide bond structures of IgG molecules

(2012) Hongcheng Liu et al.   mAbs

Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics

(2011) Igor A. Kaltashov et al.   BIOTECHNOLOGY ADVANCES

Mass spectrometry-based carboxyl footprinting of proteins: Method evaluation

(2011) Hao Zhang et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

N-terminal Glutamate to Pyroglutamate Conversionin Vivofor Human IgG2 Antibodies

(2011) Y. Diana Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Qualification of FTIR spectroscopic method for protein secondary structural analysis

(2011) Yijia Jiang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Quantitative Assessment of Protein Structural Models by Comparison of H/D Exchange MS Data with Exchange Behavior Accurately Predicted by DXCOREX

(2011) Tong Liu et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Worldwide experience with biosimilar development

(2011) Mark McCamish et al.   mAbs

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Hydrogen exchange mass spectrometry: what is it and what can it tell us?

(2010) Sean R. Marcsisin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies

(2010) Damian Houde et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Temperature Jump and Fast Photochemical Oxidation Probe Submillisecond Protein Folding

(2010) Jiawei Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biopharmaceutical benchmarks 2010

(2010) Gary Walsh   NATURE BIOTECHNOLOGY

Integrated Algorithms for High-Throughput Examination of Covalently Labeled Biomolecules by Structural Mass Spectrometry

(2009) Parminder Kaur et al.   ANALYTICAL CHEMISTRY

The sequence–structure relationship and protein function prediction

(2009) M I Sadowski et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Membrane orientation of the FMO antenna protein from Chlorobaculum tepidum as determined by mass spectrometry-based footprinting

(2009) J. Wen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Surface Mapping Using Diethylpyrocarbonate with Mass Spectrometric Detection

(2008) Vanessa Leah Mendoza et al.   ANALYTICAL CHEMISTRY

A rapid, sensitive and economical assessment of monoclonal antibody conformational stability by intrinsic tryptophan fluorescence spectroscopy

(2008) Patrick Garidel et al.   Biotechnology Journal

Monoclonal Antibodies as Innovative Therapeutics

(2008) Janice Reichert   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Protein structure and dynamics studied by mass spectrometry: H/D exchange, hydroxyl radical labeling, and related approaches

(2008) Lars Konermann et al.   JOURNAL OF MASS SPECTROMETRY

Probing protein structure by amino acid-specific covalent labeling and mass spectrometry

(2008) Vanessa Leah Mendoza et al.   MASS SPECTROMETRY REVIEWS

(Re)defining biopharmaceutical

(2008) Ronald A Rader   NATURE BIOTECHNOLOGY

Effects of Solution Conditions, Processing Parameters, and Container Materials on Aggregation of a Monoclonal Antibody during Freeze-Thawing

(2007) Lisa A. Kueltzo et al.   JOURNAL OF PHARMACEUTICAL SCIENCES