Development of near-infrared lysosomal pH-activatable fluorescent probe for real-time visualization of autophagy progression

Development of near-infrared mitochondrial polarity fluorescent probe for evaluating mitophagy in mice heart and potential cancer diagnosis

(2022) Tao Zhang et al.   CHEMICAL ENGINEERING JOURNAL

De Novo Design of A Membrane‐Anchored Probe for Multidimensional Quantification of Endocytic Dynamics

(2022) Kangqiang Qiu et al.   Advanced Healthcare Materials

Near-Infrared in and out: Observation of Autophagy during Stroke via a Lysosome-Targeting Two-Photon Viscosity-Dependent Probe

(2022) Li Chai et al.   ANALYTICAL CHEMISTRY

Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

(2022) Ju-Hyun Lee et al.   NATURE NEUROSCIENCE

PET- and ICT-Based Ratiometric Probe: An Unusual Phenomenon of Morpholine-Conjugated Fluorophore for Mitochondrial pH Mapping during Mitophagy

(2022) Subrata Munan et al.   ANALYTICAL CHEMISTRY

Viscosity activated NIR fluorescent probe for visualizing mitochondrial viscosity dynamic and fatty liver mice

(2022) Hongjun Song et al.   CHEMICAL ENGINEERING JOURNAL

A mitochondrial suitable ratiometric fluorescent probe for tracking pH change during mitophagy

(2022) Wei Shu et al.   SENSORS AND ACTUATORS B-CHEMICAL

A novel NIR-II nanoprobe for precision imaging of micro-meter sized tumor metastases of multi-organs and skin flap

(2022) Hongyue Lou et al.   CHEMICAL ENGINEERING JOURNAL

Monitoring intracellular pH fluctuation with an excited-state intramolecular proton transfer-based ratiometric fluorescent sensor

(2021) Bin Feng et al.   CHINESE CHEMICAL LETTERS

Small molecule probes for targeting autophagy

(2021) Thomas Whitmarsh-Everiss et al.   Nature Chemical Biology

Ratiometric probe with optimized permeability for visualizing lysosomal acidification during autophagy

(2021) Minggang Tian et al.   DYES AND PIGMENTS

Visualization of the pH-fluctuations in gastric ulcer living mice by the in situ near-infrared imaging

(2021) Yanyan Ma et al.   SENSORS AND ACTUATORS B-CHEMICAL

Lysosome biology in autophagy

(2020) Willa Wen-You Yim et al.   Cell Discovery

A lysosomal polarity-specific two-photon fluorescent probe for visualization of autophagy

(2020) Zixiang Yuan et al.   CHINESE CHEMICAL LETTERS

Biological Functions of Autophagy Genes: A Disease Perspective

(2019) Beth Levine et al.   CELL

Two-Photon Fluorescent Probe for Monitoring Autophagy via Fluorescence Lifetime Imaging

(2018) Liling Hou et al.   ANALYTICAL CHEMISTRY

Small fluorescent molecules for monitoring autophagic flux

(2018) Hidefumi Iwashita et al.   FEBS LETTERS

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Quantifying autophagy: Measuring LC3 puncta and autolysosome formation in cells using multispectral imaging flow cytometry

(2017) Haley R. Pugsley   METHODS

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

(2017) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Autophagy in the liver: functions in health and disease

(2017) Takashi Ueno et al.   Nature Reviews Gastroenterology & Hepatology

Optical Imaging Paves the Way for Autophagy Research

(2017) Yimin Wang et al.   TRENDS IN BIOTECHNOLOGY

Divergent Synthesis of Dihydroxanthene-Hemicyanine Fused Near-Infrared Fluorophores through the Late-Stage Amination of a Bifunctional Precursor

(2016) Michelle Jui Hsien Ong et al.   ORGANIC LETTERS

Acetaminophen-induced acute liver injury in mice

(2015) JC Mossanen et al.   LABORATORY ANIMALS

A novel image-based cytometry method for autophagy detection in living cells

(2012) Leo Li-Ying Chan et al.   Autophagy

Activation of autophagy protects against acetaminophen-induced hepatotoxicity

(2011) Hong-Min Ni et al.   HEPATOLOGY

Autophagy: assays and artifacts

(2010) Sandra Barth et al.   JOURNAL OF PATHOLOGY

Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine

(2009) Chieko Saito et al.   HEPATOLOGY