An artificial intelligence network‐guided signature for predicting outcome and immunotherapy response in lung adenocarcinoma patients based on 26 machine learning algorithms

First-Line Immunotherapy for Non–Small-Cell Lung Cancer

(2022) Martin Reck et al.   JOURNAL OF CLINICAL ONCOLOGY

A T cell resilience model associated with response to immunotherapy in multiple tumor types

(2022) Yu Zhang et al.   NATURE MEDICINE

Cross-tissue immune cell analysis reveals tissue-specific features in humans

(2022) C. Domínguez Conde et al.   SCIENCE

Profilin 1 Induces Tumor Metastasis by Promoting Microvesicle Secretion Through the ROCK 1/p-MLC Pathway in Non-Small Cell Lung Cancer

(2022) Ya Wang et al.   Frontiers in Pharmacology

Machine learning-based tumor-infiltrating immune cell-associated lncRNAs for predicting prognosis and immunotherapy response in patients with glioblastoma

(2022) Hao Zhang et al.   BRIEFINGS IN BIOINFORMATICS

Immune checkpoint modulators in cancer immunotherapy: recent advances and emerging concepts

(2022) Yuchen Wang et al.   Journal of Hematology & Oncology

Insights Gained from Single-Cell Analysis of Immune Cells in the Tumor Microenvironment

(2021) Xianwen Ren et al.   Annual Review of Immunology

Neoadjuvant Chemoradiotherapy Combined with Atezolizumab for Resectable Esophageal Adenocarcinoma: A Single Arm Phase II Feasibility Trial (PERFECT)

(2021) Tom van den Ende et al.   CLINICAL CANCER RESEARCH

Inference and analysis of cell-cell communication using CellChat

(2021) Suoqin Jin et al.   Nature Communications

Therapeutic Targeting of the Tumor Microenvironment

(2021) Leire Bejarano et al.   Cancer Discovery

Perspectives of tumor-infiltrating lymphocyte treatment in solid tumors

(2021) Shuhang Wang et al.   BMC Medicine

oncoPredict: an R package for predicting in vivo or cancer patient drug response and biomarkers from cell line screening data

(2021) Danielle Maeser et al.   BRIEFINGS IN BIOINFORMATICS

Conserved pan-cancer microenvironment subtypes predict response to immunotherapy

(2021) Alexander Bagaev et al.   CANCER CELL

Adenocarcinoma spectrum lesions of the lung: Detection, pathology and treatment strategies

(2021) L Succony et al.   CANCER TREATMENT REVIEWS

Hhex inhibits cell migration via regulating RHOA/CDC42-CFL1 axis in human lung cancer cells

(2021) Xiaopeng Li et al.   Cell Communication and Signaling

E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non–small cell lung cancer

(2021) Ke Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spatiotemporal Immune Landscape of Colorectal Cancer Liver Metastasis at Single-Cell Level

(2021) Yingcheng Wu et al.   Cancer Discovery

Upregulated Expression of Profilin1 on Dendritic Cells in Patients With Severe Aplastic Anemia

(2021) Hong Yu et al.   Frontiers in Immunology

Contradictory roles of lipid metabolism in immune response within the tumor microenvironment

(2021) Weina Yu et al.   Journal of Hematology & Oncology

Intratumor heterogeneity: the hidden barrier to immunotherapy against MSI tumors from the perspective of IFN-γ signaling and tumor-infiltrating lymphocytes

(2021) Wantao Wu et al.   Journal of Hematology & Oncology

Tumour‐derived small extracellular vesicles suppress CD8+ T cell immune function by inhibiting SLC6A8‐mediated creatine import in NPM1‐mutated acute myeloid leukaemia

(2021) Meixi Peng et al.   Journal of Extracellular Vesicles

Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

(2020) David A. Braun et al.   NATURE MEDICINE

Direct targeting of HSP90 with daurisoline destabilizes β-catenin to suppress lung cancer tumorigenesis

(2020) Xiao-Hui Huang et al.   CANCER LETTERS

A novel scoring method based on RNA‐Seq immunograms describing individual cancer‐immunity interactions

(2020) Yukari Kobayashi et al.   CANCER SCIENCE

Overcoming immunotherapy resistance in non-small cell lung cancer (NSCLC) - novel approaches and future outlook

(2020) Lena Horvath et al.   Molecular Cancer

Cancer-cell-secreted CXCL11 promoted CD8+ T cells infiltration through docetaxel-induced-release of HMGB1 in NSCLC

(2019) Qun Gao et al.   Journal for ImmunoTherapy of Cancer

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Machine learning for clinical decision support in infectious diseases: A narrative review of current applications

(2019) Nathan Peiffer-Smadja et al.   CLINICAL MICROBIOLOGY AND INFECTION

Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple-negative breast and serous ovarian cancers

(2018) N J Birkbak et al.   ANNALS OF ONCOLOGY

The Immune Landscape of Cancer

(2018) Vésteinn Thorsson et al.   IMMUNITY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

TIP: A web server for resolving tumor immunophenotype profiling

(2018) Liwen Xu et al.   CANCER RESEARCH

CCDC85B promotes non-small cell lung cancer cell proliferation and invasion

(2018) Yangyang Feng et al.   MOLECULAR CARCINOGENESIS

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

(2018) Sanjeev Mariathasan et al.   NATURE

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

(2018) Peng Jiang et al.   NATURE MEDICINE

Maftools: efficient and comprehensive analysis of somatic variants in cancer

(2018) Anand Mayakonda et al.   GENOME RESEARCH

Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas

(2018) S. R. Rosario et al.   Nature Communications

Machine learning for epigenetics and future medical applications

(2017) Lawrence B. Holder et al.   Epigenetics

IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade

(2017) Mark Ayers et al.   JOURNAL OF CLINICAL INVESTIGATION

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

(2017) Pornpimol Charoentong et al.   Cell Reports

Potential Predictive Value of TP53 and KRAS Mutation Status for Response to PD-1 Blockade Immunotherapy in Lung Adenocarcinoma

(2016) Zhong-Yi Dong et al.   CLINICAL CANCER RESEARCH

Novel therapeutic targets on the horizon for lung cancer

(2016) Wan-Ling Tan et al.   LANCET ONCOLOGY

Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade

(2016) Tavi Nathanson et al.   Cancer Immunology Research

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

(2015) E. M. Van Allen et al.   SCIENCE

pRRophetic: An R Package for Prediction of Clinical Chemotherapeutic Response from Tumor Gene Expression Levels

(2014) Paul Geeleher et al.   PLoS One

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

CMAP: Complement Map Database

(2013) Kun Yang et al.   BIOINFORMATICS

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

Predictive Gene Signature in MAGE-A3 Antigen-Specific Cancer Immunotherapy

(2013) Fernando Ulloa-Montoya et al.   JOURNAL OF CLINICAL ONCOLOGY

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications