N6-Methyladenosine-modified circSAV1 triggers ferroptosis in COPD through recruiting YTHDF1 to facilitate the translation of IREB2

The multifaceted role of ferroptosis in liver disease

(2022) Junyi Chen et al.   CELL DEATH AND DIFFERENTIATION

Specific expression and functions of circular RNAs

(2022) Sema Misir et al.   CELL DEATH AND DIFFERENTIATION

CircMET promotes tumor proliferation by enhancing CDKN2A mRNA decay and upregulating SMAD3

(2022) Lei Yang et al.   Molecular Cancer

Characterization of the COPD alveolar niche using single-cell RNA sequencing

(2022) Maor Sauler et al.   Nature Communications

Circular RNAs: Characterization, cellular roles, and applications

(2022) Chu-Xiao Liu et al.   CELL

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The aberrant cross-talk of epithelium–macrophages via METTL3-regulated extracellular vesicle miR-93 in smoking-induced emphysema

(2021) Haibo Xia et al.   CELL BIOLOGY AND TOXICOLOGY

mRNA modifications in cardiovascular biology and disease: with a focus on m6A modification

(2021) Rajesh Kumari et al.   CARDIOVASCULAR RESEARCH

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019

(2021) Marissa B Reitsma et al.   LANCET

A global overview of genetically interpretable multimorbidities among common diseases in the UK Biobank

(2021) Guiying Dong et al.   Genome Medicine

Circular RNA ZNF609/CKAP5 mRNA interaction regulates microtubule dynamics and tumorigenicity

(2021) Francesca Rossi et al.   MOLECULAR CELL

RNAInter v4.0: RNA interactome repository with redefined confidence scoring system and improved accessibility

(2021) Juanjuan Kang et al.   NUCLEIC ACIDS RESEARCH

Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis

(2021) Aimin Wu et al.   Redox Biology

Ferroptosis involves in intestinal epithelial cell death in ulcerative colitis

(2020) Minyi Xu et al.   Cell Death & Disease

Fenton reaction-independent ferroptosis therapy via glutathione and iron redox couple sequentially triggered lipid peroxide generator

(2020) Yu-Jing He et al.   BIOMATERIALS

Therapeutic RNA Strategies for Chronic Obstructive Pulmonary Disease

(2020) Dan Mei et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Quercetin alleviates acute kidney injury by inhibiting ferroptosis

(2020) Yue Wang et al.   Journal of Advanced Research

Ferroptosis: machinery and regulation

(2020) Xin Chen et al.   Autophagy

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

(2020) Theo Vos et al.   LANCET

Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. The 2020 GOLD Science Committee Report on COVID-19 and Chronic Obstructive Pulmonary Disease

(2020) David M. G. Halpin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Epigenetics and pulmonary diseases in the horizon of precision medicine: a review

(2020) Giuditta Benincasa et al.   EUROPEAN RESPIRATORY JOURNAL

Deletion of ferritin H in neurons counteracts the protective effect of melatonin against traumatic brain injury‐induced ferroptosis

(2020) Tongyu Rui et al.   JOURNAL OF PINEAL RESEARCH

Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway

(2020) Enyong Dai et al.   Nature Communications

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

(2019) Masahiro Yoshida et al.   Nature Communications

Regulation of gene expression by cis-acting long non-coding RNAs

(2019) Noa Gil et al.   NATURE REVIEWS GENETICS

N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

(2019) Ri-Xin Chen et al.   Nature Communications

m6A mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to induce NSCLC drug resistance and metastasis

(2019) Dan Jin et al.   Journal of Hematology & Oncology

m6A facilitates hippocampus-dependent learning and memory through YTHDF1

(2018) Hailing Shi et al.   NATURE

Overcoming cellular barriers for RNA therapeutics

(2017) Steven F Dowdy   NATURE BIOTECHNOLOGY

Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations

(2016) Jlenia Guarnerio et al.   CELL

Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice

(2016) Suzanne M Cloonan et al.   NATURE MEDICINE

SRAMP: prediction of mammalian N6-methyladenosine (m6A) sites based on sequence-derived features

(2016) Yuan Zhou et al.   NUCLEIC ACIDS RESEARCH

5′ UTR m6A Promotes Cap-Independent Translation

(2015) Kate D. Meyer et al.   CELL

Systemic inflammation up-regulates serum hepcidin in exacerbations and stabile chronic obstructive pulmonary disease

(2015) Leida Tandara et al.   CLINICAL BIOCHEMISTRY

IRP2 Regulates Breast Tumor Growth

(2013) Wei Wang et al.   CANCER RESEARCH

The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo

(2011) Toshiro Moroishi et al.   Cell Metabolism

Particulate Matter in Cigarette Smoke Alters Iron Homeostasis to Produce a Biological Effect

(2008) Andrew J. Ghio et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE