Profiling TREM2 expression in amyotrophic lateral sclerosis

Blocking immune cell infiltration of the central nervous system to tame Neuroinflammation in Amyotrophic lateral sclerosis

(2022) Stefano Garofalo et al.   BRAIN BEHAVIOR AND IMMUNITY

Lack of association between TREM2 rs75932628 variant and amyotrophic lateral sclerosis

(2021) Vasileios Siokas et al.   MOLECULAR BIOLOGY REPORTS

Microglia‐Related Gene Triggering Receptor Expressed in Myeloid Cells 2 ( TREM2 ) Is Upregulated in the Substantia Nigra of Progressive Supranuclear Palsy

(2020) Javier Sánchez‐Ruiz de Gordoa et al.   MOVEMENT DISORDERS

Enhancing protective microglial activities with a dual function TREM 2 antibody to the stalk region

(2020) Kai Schlepckow et al.   EMBO Molecular Medicine

Motor cortex transcriptome reveals microglial key events in amyotrophic lateral sclerosis

(2020) Oriol Dols-Icardo et al.   Neurology-Neuroimmunology & Neuroinflammation

Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival

(2020) Aude Chiot et al.   NATURE NEUROSCIENCE

Detection and Quantification of Novel C‐terminal TDP‐43 Fragments in ALS‐TDP

(2020) Emily Feneberg et al.   BRAIN PATHOLOGY

Brain-Gut-Microbiota Axis in Alzheimer’s Disease

(2019) Karol Kowalski et al.   Journal of Neurogastroenterology and Motility

TREM2 Variants and Neurodegenerative Diseases: A Systematic Review and Meta-Analysis

(2019) Sheng-Lan Zhou et al.   JOURNAL OF ALZHEIMERS DISEASE

TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

(2019) Jorge L. Del-Aguila et al.   Molecular Neurodegeneration

Single-cell analysis reveals T cell infiltration in old neurogenic niches

(2019) Ben W. Dulken et al.   NATURE

TREM Receptors Connecting Bowel Inflammation to Neurodegenerative Disorders

(2019) Gianfranco Natale et al.   Cells

The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease

(2019) Alessandra Webers et al.   IMMUNOLOGY AND CELL BIOLOGY

The endotoxin hypothesis of neurodegeneration

(2019) Guy C. Brown   Journal of Neuroinflammation

Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant carriers

(2019) Nicholas J. Ashton et al.   Alzheimers Research & Therapy

Convergence between Microglia and Peripheral Macrophages Phenotype during Development and Neuroinflammation

(2019) Francesca Grassivaro et al.   JOURNAL OF NEUROSCIENCE

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

(2018) Aleksandra Deczkowska et al.   CELL

The increasing importance of environmental conditions in amyotrophic lateral sclerosis

(2018) Javier Riancho et al.   INTERNATIONAL JOURNAL OF BIOMETEOROLOGY

Soluble TREM2 and biomarkers of central and peripheral inflammation in neurodegenerative disease

(2018) L.M. Bekris et al.   JOURNAL OF NEUROIMMUNOLOGY

Increased Expression of TREM2 in Peripheral Blood of Alzheimer's Disease Patients

(2018) Nan Hu et al.   JOURNAL OF ALZHEIMERS DISEASE

TREM2 — a key player in microglial biology and Alzheimer disease

(2018) Tyler K. Ulland et al.   Nature Reviews Neurology

Current state of Alzheimer’s fluid biomarkers

(2018) José Luis Molinuevo et al.   ACTA NEUROPATHOLOGICA

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

TREM2 in Neurodegenerative Diseases

(2017) Taylor R. Jay et al.   Molecular Neurodegeneration

Ensembl 2018

(2017) Daniel R Zerbino et al.   NUCLEIC ACIDS RESEARCH

Role of Neuroinflammation in Amyotrophic Lateral Sclerosis: Cellular Mechanisms and Therapeutic Implications

(2017) Jia Liu et al.   Frontiers in Immunology

A data-driven approach links microglia to pathology and prognosis in amyotrophic lateral sclerosis

(2017) Johnathan Cooper-Knock et al.   Acta Neuropathologica Communications

Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status

(2016) Laura Piccio et al.   ACTA NEUROPATHOLOGICA

Cerebrospinal fluid sTREM2 levels are associated with gray matter volume increases and reduced diffusivity in early Alzheimer's disease

(2016) Juan Domingo Gispert et al.   Alzheimers & Dementia

sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers

(2016) Marc Suárez‐Calvet et al.   EMBO Molecular Medicine

ALS: A bucket of genes, environment, metabolism and unknown ingredients

(2016) Mónica Zufiría et al.   PROGRESS IN NEUROBIOLOGY

Cerebrospinal fluid soluble TREM2 in aging and Alzheimer’s disease

(2016) Kristi Henjum et al.   Alzheimers Research & Therapy

TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus

(2016) Naiara Celarain et al.   Clinical Epigenetics

Specific Legislation on Biobanks in Spain

(2015) Isabel M García-Merino et al.   BIOPRESERVATION AND BIOBANKING

TREM2 mRNA Expression in Leukocytes Is Increased in Alzheimer’s Disease and Schizophrenia

(2015) Yoko Mori et al.   PLoS One

Specific Legislation on Biobanks in Spain

(2015) Isabel M García-Merino et al.   Biopreservation and Biobanking

Coding variants in TREM2 increase risk for Alzheimer's disease

(2014) Sheng Chih Jin et al.   HUMAN MOLECULAR GENETICS

Regulating amyloidogenesis through the natural triggering receptor expressed in myeloid/microglial cells 2 (TREM2)

(2014) Brandon M. Jones et al.   Frontiers in Cellular Neuroscience

TREM2Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis

(2014) Janet Cady et al.   JAMA Neurology

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease

(2013) Sruti Rayaprolu et al.   Molecular Neurodegeneration

Microglia and neurodegeneration: The role of systemic inflammation

(2012) Colm Cunningham   GLIA

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE