Photothermal “nano-dot” reactivate “immune-hot” for tumor treatment via reprogramming cancer cells metabolism

Microbiotic nanomedicine for tumor-specific chemotherapy-synergized innate/adaptive antitumor immunity

(2022) Wencheng Wu et al.   Nano Today

Dual Closed-Loop of Catalyzed Lactate Depletion and Immune Response to Potentiate Photothermal Immunotherapy

(2022) Xiao Zheng et al.   ACS Applied Materials & Interfaces

Photothermal-triggered immunogenic nanotherapeutics for optimizing osteosarcoma therapy by synergizing innate and adaptive immunity

(2022) Kaiyuan Liu et al.   BIOMATERIALS

A bispecific nanomodulator to potentiate photothermal cancer immunotherapy

(2022) Lei Zhou et al.   Nano Today

Biocompatible Inorganic Nanoagent for Efficient Synergistic Tumor Treatment with Augmented Antitumor Immunity

(2022) Juanjuan Su et al.   Small

Nanoparticle-enhanced radiotherapy synergizes with PD-L1 blockade to limit post-surgical cancer recurrence and metastasis

(2022) Xin Guan et al.   Nature Communications

Radical induced quartet photosensitizers with high 1O2 production for in vivo cancer photodynamic therapy

(2021) Feng Xu et al.   Science China-Chemistry

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

(2021) McLane J. Watson et al.   NATURE

Cancer-activated doxorubicin prodrug nanoparticles induce preferential immune response with minimal doxorubicin-related toxicity

(2021) Suah Yang et al.   BIOMATERIALS

Mild Magnetic Hyperthermia-Activated Innate Immunity for Liver Cancer Therapy

(2021) Jiong Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-Phenolic Network-Enabled Lactic Acid Consumption Reverses Immunosuppressive Tumor Microenvironment for Sonodynamic Therapy

(2021) Zhan Zhang et al.   ACS Nano

Cancer immunogenic cell death via photo-pyroptosis with light-sensitive Indoleamine 2,3-dioxygenase inhibitor conjugate

(2021) Yang Lu et al.   BIOMATERIALS

NIR Light‐Driving Barrier‐Free Group Rotation in Nanoparticles with an 88.3% Photothermal Conversion Efficiency for Photothermal Therapy

(2020) Dongmei Xi et al.   ADVANCED MATERIALS

Openwork@Dendritic Mesoporous Silica Nanoparticles for Lactate Depletion and Tumor Microenvironment Regulation

(2020) Jie Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Curcumin circumvent lactate-induced chemoresistance in hepatic cancer cells through modulation of hydroxycarboxylic acid receptor-1

(2020) Vivek Kumar Soni et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Chemistry of Advanced Nanomedicines in Cancer Cell Metabolism Regulation

(2020) Bowen Yang et al.   Advanced Science

Engineering of Cascade-Responsive Nanoplatform to Inhibit Lactate Efflux for Enhanced Tumor Chemo-Immunotherapy

(2020) Ke Li et al.   ACS Nano

Activity‐Based NIR Enzyme Fluorescent Probes for the Diagnosis of Tumors and Image‐Guided Surgery

(2020) Juyoung Yoon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering Prodrug Nanomedicine for Cancer Immunotherapy

(2020) Bin Yang et al.   Advanced Science

Responsive and activable nanomedicines for remodeling the tumor microenvironment

(2020) Yinlong Zhang et al.   Nature Protocols

The oncogenic and clinical implications of lactate induced immunosuppression in the tumour microenvironment

(2020) Conall Hayes et al.   CANCER LETTERS

Tailor-Made Semiconducting Polymers for Second Near-Infrared Photothermal Therapy of Orthotopic Liver Cancer

(2019) Tingting Sun et al.   ACS Nano

Ferrimagnetic Vortex Nanoring-Mediated Mild Magnetic Hyperthermia Imparts Potent Immunological Effect for Treating Cancer Metastasis

(2019) Xiaoli Liu et al.   ACS Nano

Local T regulatory cells depletion by an integrated nanodrug system for efficient chem-immunotherapy of tumor

(2019) Fan Gao et al.   Science China-Chemistry

Catalytically Selective Chemotherapy from Tumor‐Metabolic Generated Lactic Acid

(2019) Zhimin Tian et al.   Small

Intra/Extracellular Lactic Acid Exhaustion for Synergistic Metabolic Therapy and Immunotherapy of Tumors

(2019) Fan Gao et al.   ADVANCED MATERIALS

Photo-controlled liquid metal nanoparticle-enzyme for starvation/photothermal therapy of tumor by win-win cooperation

(2019) Jing-Jing Hu et al.   BIOMATERIALS

Syringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence

(2019) Chanyoung Song et al.   Nature Communications

Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy

(2019) Liping Huang et al.   Nature Communications

Normalizing Tumor Microenvironment Based on Photosynthetic Abiotic/Biotic Nanoparticles

(2018) Diwei Zheng et al.   ACS Nano

Nanoparticle-Mediated Remodeling of the Tumor Microenvironment to Enhance Immunotherapy

(2018) Sara Musetti et al.   ACS Nano

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

Therapeutic targets in cancer cell metabolism and autophagy

(2012) Heesun Cheong et al.   NATURE BIOTECHNOLOGY