Structures of the intermediates in the catalytic cycle of mitochondrial cytochrome c oxidase

Evolution of quinol oxidation within the heme‑copper oxidoreductase superfamily

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Structural basis of mammalian complex IV inhibition by steroids

(2022) Justin M. Di Trani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture of bacterial respiratory chains

(2021) Ville R. I. Kaila et al.   NATURE REVIEWS MICROBIOLOGY

Atomic structures of respiratory complex III2, complex IV, and supercomplex III2-IV from vascular plants

(2021) Maria Maldonado et al.   eLife

A Resonance Raman Marker Band Characterizes the Slow and Fast Form of Cytochrome c Oxidase

(2021) Fabian Kruse et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Redox-Active Tyrosine Is Essential for Proton Pumping in Cytochrome c Oxidase

(2021) Margareta R. A. Blomberg   Frontiers in Chemistry

Critical roles of the CuB site in efficient proton pumping as revealed by crystal structures of mammalian cytochrome c oxidase catalytic intermediates

(2021) Atsuhiro Shimada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The three-spin intermediate at the O–O cleavage and proton-pumping junction in heme–Cu oxidases

(2021) Anex Jose et al.   SCIENCE

Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase

(2021) F. Kolbe et al.   Nature Communications

The structure of the oxidized state of cytochrome c oxidase - experiments and theory compared

(2020) Margareta R.A. Blomberg   JOURNAL OF INORGANIC BIOCHEMISTRY

Thermodynamic efficiency, reversibility, and degree of coupling in energy conservation by the mitochondrial respiratory chain

(2020) Mårten Wikström et al.   Communications Biology

Snapshot of an oxygen intermediate in the catalytic reaction of cytochrome c oxidase

(2019) Izumi Ishigami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-dose X-ray structure analysis of cytochrome c oxidase utilizing high-energy X-rays

(2019) Go Ueno et al.   JOURNAL OF SYNCHROTRON RADIATION

Monomeric structure of an active form of bovine cytochrome c oxidase

(2019) Kyoko Shinzawa-Itoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the cytochrome aa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site

(2019) Jingjing Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxygen Activation and Energy Conservation by Cytochrome c Oxidase

(2018) Mårten Wikström et al.   CHEMICAL REVIEWS

Structure of yeast cytochrome c oxidase in a supercomplex with cytochrome bc1

(2018) Andrew M. Hartley et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM structure of the yeast respiratory supercomplex

(2018) Sorbhi Rathore et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain

(2017) James A Letts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain

(2017) James A Letts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Serial femtosecond crystallography structure of cytochrome c oxidase at room temperature

(2017) Rebecka Andersson et al.   Scientific Reports

Splitting of the O–O bond at the heme-copper catalytic site of respiratory oxidases

(2017) Federica Poiana et al.   Science Advances

Mechanism of Oxygen Reduction in Cytochrome c Oxidase and the Role of the Active Site Tyrosine

(2016) Margareta R. A. Blomberg   BIOCHEMISTRY

The Mg2+-containing Water Cluster of Mammalian CytochromecOxidase Collects Four Pumping Proton Equivalents in Each Catalytic Cycle

(2016) Naomine Yano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The architecture of the mammalian respirasome

(2016) Jinke Gu et al.   NATURE

Protonation of the binuclear active site in cytochrome c oxidase decreases the reduction potential of CuB

(2015) Margareta R.A. Blomberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Reaction Mechanism of Cytochrome c Oxidase

(2015) Shinya Yoshikawa et al.   CHEMICAL REVIEWS

New Perspectives on Proton Pumping in Cellular Respiration

(2015) Mårten Wikström et al.   CHEMICAL REVIEWS

Proton-coupled electron transfer and the role of water molecules in proton pumping by cytochromecoxidase

(2015) Vivek Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of damage-free crystal structure of an X-ray–sensitive protein using an XFEL

(2014) Kunio Hirata et al.   NATURE METHODS

Renormalization of myoglobin-ligand binding energetics by quantum many-body effects

(2014) C. Weber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational study of the activated OH state in the catalytic mechanism of cytochrome c oxidase

(2013) V. Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment

(2011) Theresa Tiefenbrunn et al.   PLoS One

The Structure of cbb3 Cytochrome Oxidase Provides Insights into Proton Pumping

(2010) S. Buschmann et al.   SCIENCE

Redox-Dependent Conformational Changes in CytochromecOxidase Suggest a Gating Mechanism for Proton Uptake

(2009) Ling Qin et al.   BIOCHEMISTRY

High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: New insights into the active site and the proton transfer pathways

(2009) Juergen Koepke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Cytochrome c oxidase: exciting progress and remaining mysteries

(2008) Peter Brzezinski et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

The Protonation State of the Cross-linked Tyrosine during the Catalytic Cycle of CytochromecOxidase

(2008) Elena A. Gorbikova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The proton donor for OO bond scission by cytochrome c oxidase

(2008) E. A. Gorbikova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA