Immunogenic Cell Death Inducing Metal Complexes for Cancer Therapy

A mitochondria-localized iridium(iii) photosensitizer for two-photon photodynamic immunotherapy against melanoma

(2023) Lili Wang et al.   Chemical Science

Metal-based anticancer agents as immunogenic cell death inducers: the past, present, and future

(2022) Sajal Sen et al.   CHEMICAL SOCIETY REVIEWS

Photo‐Reduction with NIR Light of Nucleus‐Targeting Pt IV Nanoparticles for Combined Tumor‐Targeted Chemotherapy and Photodynamic Immunotherapy

(2022) Dengshuai Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Biodegradable Iridium(III) Coordination Polymer for Enhanced Two‐Photon Photodynamic Therapy Using an Apoptosis–Ferroptosis Hybrid Pathway

(2022) Libing Ke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rising Interest in the Development of Metal Complexes in Cancer Immunotherapy

(2022) Zhi‐Yuan Li et al.   Chemistry-An Asian Journal

Target Profiling of an Iridium(III)-Based Immunogenic Cell Death Inducer Unveils the Engagement of Unfolded Protein Response Regulator BiP

(2022) Xiaolin Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Encapsulation of Platinum Prodrugs into PC7A Polymeric Nanoparticles Combined with Immune Checkpoint Inhibitors for Therapeutically Enhanced Multimodal Chemotherapy and Immunotherapy by Activation of the STING Pathway

(2022) Xiangjie Gao et al.   Advanced Science

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Copper‐Based Nanoscale Coordination Polymers Augmented Tumor Radioimmunotherapy for Immunogenic Cell Death Induction and T‐Cell Infiltration

(2021) Yuxiang Wang et al.   Small

Ferroptosis‐Enhanced Cancer Immunity by a Ferrocene‐Appended Iridium(III) Diphosphine Complex

(2021) Wen‐Jin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Auranofin and Cold Atmospheric Plasma Synergize to Trigger Distinct Cell Death Mechanisms and Immunogenic Responses in Glioblastoma

(2021) Jinthe Van Loenhout et al.   Cells

A Multiaction and Multitarget Ru(II)-Pt(IV) Conjugate Combining Cancer Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers

(2020) Johannes Karges et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PT-112 induces immunogenic cell death and synergizes with immune checkpoint blockers in mouse tumor models

(2020) Takahiro Yamazaki et al.   OncoImmunology

A Photocaged, Water-Oxidizing, and Nucleolus-Targeted Pt(IV) Complex with a Distinct Anticancer Mechanism

(2020) Zhiqin Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PlatinER: a Highly Potent Anticancer Platinum(II) Complex that induces Endoplasmic Reticulum Stress‐driven Immunogenic Cell Death

(2020) Max Jing Rui Tham et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Immunogenic Cell Death of Breast Cancer Stem Cells by an Endoplasmic Reticulum‐Targeting Copper(II) Complex

(2020) Pooja Kaur et al.   CHEMBIOCHEM

Clinically Relevant Chemotherapeutics Have the Ability to Induce Immunogenic Cell Death in Non-Small Cell Lung Cancer

(2020) Tal Flieswasser et al.   Cells

Intratumoral Cancer Chemotherapy with a Carrier-Based Immunogenic Cell-Death Eliciting Platinum (IV) Agent

(2020) Chad Groer et al.   MOLECULAR PHARMACEUTICS

An ER‐Targeting Iridium(III) Complex That Induces Immunogenic Cell Death in Non‐Small‐Cell Lung Cancer

(2020) Lili Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rationally Designed Redox-Active Au(I) N-Heterocyclic Carbene: An Immunogenic Cell Death Inducer

(2020) Sajal Sen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pt(IV) Bifunctional Prodrug Containing 2-(2-Propynyl)octanoato Axial Ligand: Induction of Immunogenic Cell Death on Colon Cancer

(2019) Maurizio Sabbatini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial

(2019) Leonie Voorwerk et al.   NATURE MEDICINE

Inadequate BiP availability defines endoplasmic reticulum stress

(2019) Milena Vitale et al.   eLife

Immunogenic cell death in cancer therapy: Present and emerging inducers

(2019) Jingyi Zhou et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Clinical evidence that immunogenic cell death sensitizes to PD-1/PD-L1 blockade

(2019) Oliver Kepp et al.   OncoImmunology

Patterns of platinum drug use in an acute care setting: a retrospective study

(2018) Evangeline Armstrong-Gordon et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Recent progress in polymer-based platinum drug delivery systems

(2018) Haihua Xiao et al.   PROGRESS IN POLYMER SCIENCE

Immunogenic cell death in anticancer chemotherapy and its impact on clinical studies

(2018) Qiang Wang et al.   CANCER LETTERS

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

(2017) Peter M Bruno et al.   NATURE MEDICINE

Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics

(2017) Abhishek D. Garg et al.   OncoImmunology

Anticancer metal drugs and immunogenic cell death

(2016) Alessio Terenzi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study

(2016) Corey J Langer et al.   LANCET ONCOLOGY

Induction of Immunogenic Cell Death by Chemotherapeutic Platinum Complexes

(2015) Daniel Yuan Qiang Wong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists

(2013) T Yamazaki et al.   CELL DEATH AND DIFFERENTIATION

Inducers of immunogenic cancer cell death

(2013) Aleksandra M. Dudek et al.   CYTOKINE & GROWTH FACTOR REVIEWS

A Novel Chemoimmunomodulating Property of Docetaxel: Suppression of Myeloid-Derived Suppressor Cells in Tumor Bearers

(2010) K. N. Kodumudi et al.   CLINICAL CANCER RESEARCH

Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress

(2010) I Martins et al.   ONCOGENE

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

(2009) Theocharis Panaretakis et al.   EMBO JOURNAL

Inflaming metastasis

(2009) Alberto Mantovani   NATURE

Immunogenic death of colon cancer cells treated with oxaliplatin

(2009) A Tesniere et al.   ONCOGENE

Non-DNA-binding platinum anticancer agents: Cytotoxic activities of platinum-phosphato complexes towards human ovarian cancer cells

(2008) R. N. Bose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA