Sepsis-induced brain dysfunction

Intravenous immunoglobulins prevent the breakdown of the blood-brain barrier in experimentally induced sepsis

(2012) Figen Esen et al.   CRITICAL CARE MEDICINE

The relationship between delirium duration, white matter integrity, and cognitive impairment in intensive care unit survivors as determined by diffusion tensor imaging

(2012) Alessandro Morandi et al.   CRITICAL CARE MEDICINE

Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by Increasing superoxide production

(2011) Seok Joon Won et al.   ANNALS OF NEUROLOGY

Statins and Brain Dysfunction

(2011) Alessandro Morandi et al.   CHEST

Brainstem responses can predict death and delirium in sedated patients in intensive care unit*

(2011) Tarek Sharshar et al.   CRITICAL CARE MEDICINE

Traffic of leukocytes and cytokine up-regulation in the central nervous system in sepsis

(2011) Clarissa M. Comim et al.   INTENSIVE CARE MEDICINE

Neuro-oxidative-nitrosative stress in sepsis

(2011) Ronan MG Berg et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regional difference in inflammatory response to LPS-injection in the brain: Role of microglia cell density

(2011) Cristina Pintado et al.   JOURNAL OF NEUROIMMUNOLOGY

Septic encephalopathy: Inflammation in man and mouse

(2011) Alexander Jacob et al.   NEUROCHEMISTRY INTERNATIONAL

Neural aspects of immunomodulation: Focus on the vagus nerve

(2010) Julian F. Thayer et al.   BRAIN BEHAVIOR AND IMMUNITY

Delirium as a predictor of long-term cognitive impairment in survivors of critical illness

(2010) Timothy D. Girard et al.   CRITICAL CARE MEDICINE

C5a alters blood-brain barrier integrity in experimental lupus

(2010) Alexander Jacob et al.   FASEB JOURNAL

Neutrophils: Cinderella of innate immune system

(2010) V. Kumar et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis

(2010) Theodore J. Iwashyna et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Brain-derived neurotrophic factor and neuron-specific enolase, but not S100β, levels are associated to the occurrence of delirium in intensive care unit patients

(2010) Carmen Grandi et al.   JOURNAL OF CRITICAL CARE

Systemic infection and delirium: when cytokines and acetylcholine collide

(2010) Willem A van Gool et al.   LANCET

Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: a multicentre, double-blind, placebo-controlled randomised trial

(2010) Maarten MJ van Eijk et al.   LANCET

Cytokines and the immunomodulatory function of the vagus nerve

(2009) G.R. Johnston et al.   BRITISH JOURNAL OF ANAESTHESIA

Continuous electroencephalography in the medical intensive care unit*

(2009) Mauro Oddo et al.   CRITICAL CARE MEDICINE

Sepsis-Associated Encephalopathy: A Magnetic Resonance Imaging and Spectroscopy Study

(2009) Fernando A Bozza et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Role of Endothelial TLR4 for Neutrophil Recruitment into Central Nervous System Microvessels in Systemic Inflammation

(2009) H. Zhou et al.   JOURNAL OF IMMUNOLOGY

NOS2 Gene Deficiency Protects from Sepsis-Induced Long-Term Cognitive Deficits

(2009) M. Weberpals et al.   JOURNAL OF NEUROSCIENCE

Cerebral Microbleeds Are Frequent in Infective Endocarditis

(2009) Isabelle Klein et al.   STROKE

Role of endothelial nitric oxide synthase-derived nitric oxide in activation and dysfunction of cerebrovascular endothelial cells during early onsets of sepsis

(2008) Osamu Handa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines

(2008) Christopher J. Henry et al.   BRAIN BEHAVIOR AND IMMUNITY

Detachment of Brain Pericytes from the Basal Lamina is Involved in Disruption of the Blood–Brain Barrier Caused by Lipopolysaccharide-Induced Sepsis in Mice

(2008) Tsuyoshi Nishioku et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Sepsis induces brain mitochondrial dysfunction

(2008) Joana da Costa P. d’Avila et al.   CRITICAL CARE MEDICINE

Therapeutic approaches to reduce systemic inflammation in septic-associated neurologic complications

(2008) M. L. Wratten   EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Modulation of astrocytic metabolic phenotype by proinflammatory cytokines

(2008) Mathilde Gavillet et al.   GLIA

Factors associated with posttraumatic stress symptoms in a prospective cohort of patients after abdominal sepsis: a nomogram

(2008) Kimberly R. Boer et al.   INTENSIVE CARE MEDICINE

Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism

(2008) Alexander Semmler et al.   Journal of Neuroinflammation

Neurotoxic Activation of Microglia Is Promoted by a Nox1-Dependent NADPH Oxidase

(2008) C. Cheret et al.   JOURNAL OF NEUROSCIENCE

The Effects of Riluzole on Neurological, Brain Biochemical, and Histological Changes in Early and Late Term of Sepsis in Rats

(2008) Hale Z. Toklu et al.   JOURNAL OF SURGICAL RESEARCH

Risk factors for the development of early-onset delirium and the subsequent clinical outcome in mechanically ventilated patients

(2007) Shu-Min Lin et al.   JOURNAL OF CRITICAL CARE

Injury of the Blood Brain Barrier and Up-Regulation of ICAM-1 in Polymicrobial Sepsis

(2007) Stefan Hofer et al.   JOURNAL OF SURGICAL RESEARCH

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE

TNF is a key mediator of septic encephalopathy acting through its receptor, TNF receptor-1

(2007) Jessy J. Alexander et al.   NEUROCHEMISTRY INTERNATIONAL