Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium

Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin

(2014) Haixia Gong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

(2013) Monica Giannotta et al.   DEVELOPMENTAL CELL

The Par3/Par6/aPKC complex and epithelial cell polarity

(2013) Jia Chen et al.   EXPERIMENTAL CELL RESEARCH

Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells

(2013) P. Mendoza et al.   JOURNAL OF CELL SCIENCE

The Wnt/Planar Cell Polarity Signaling Pathway Contributes to the Integrity of Tight Junctions in Brain Endothelial Cells

(2013) Cédric Artus et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy

(2012) Yanjun Li et al.   Autophagy

A Critical Role for Phosphatidylinositol (3,4,5)-Trisphosphate–Dependent Rac Exchanger 1 in Endothelial Junction Disruption and Vascular Hyperpermeability

(2012) Ram P. Naikawadi et al.   CIRCULATION RESEARCH

Rab5 in the Regulation of Cell Motility and Invasion

(2012) Dwayne G. Stupack et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and down-regulation

(2012) Xiaofeng Jiang et al.   FASEB JOURNAL

Relocalization of Junctional Adhesion Molecule A during Inflammatory Stimulation of Brain Endothelial Cells

(2012) S. M. Stamatovic et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of Rac activity alleviates lipopolysaccharide-induced acute pulmonary injury in mice

(2011) Hong-yi Yao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Regulation of Endothelial Permeability via Paracellular and Transcellular Transport Pathways

(2010) Yulia Komarova et al.   Annual Review of Physiology

Distal Interactions within the par3−VE-Cadherin Complex,

(2010) Robert C. Tyler et al.   BIOCHEMISTRY

VE-cadherin: at the front, center, and sides of endothelial cell organization and function

(2010) Elizabeth S Harris et al.   CURRENT OPINION IN CELL BIOLOGY

β1 Integrin Establishes Endothelial Cell Polarity and Arteriolar Lumen Formation via a Par3-Dependent Mechanism

(2010) Ann C. Zovein et al.   DEVELOPMENTAL CELL

Rab1 GTPase promotes expression of β-adrenergic receptors in rat pulmonary microvascular endothelial cells

(2010) Yuncheng Li et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The PI3K p110α isoform regulates endothelial adherens junctions via Pyk2 and Rac1

(2010) Robert J. Cain et al.   JOURNAL OF CELL BIOLOGY

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

(2010) M. G. Lampugnani et al.   JOURNAL OF CELL SCIENCE

The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells

(2010) Richard Daneman et al.   PLoS One

Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane

(2010) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab GTPase Regulation of VEGFR2 Trafficking and Signaling in Endothelial Cells

(2009) Helen M. Jopling et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lipopolysaccharide-induced endothelial barrier breakdown is cyclic adenosine monophosphate dependent in vivo and in vitro*

(2009) Nicolas Schlegel et al.   CRITICAL CARE MEDICINE

The Regulation of Vascular Endothelial Growth Factor-induced Microvascular Permeability Requires Rac and Reactive Oxygen Species

(2009) Elizabeth Monaghan-Benson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability

(2009) Natalia V. Bogatcheva et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Golgi-associated cPLA2α Regulates Endothelial Cell–Cell Junction Integrity by Controlling the Trafficking of Transmembrane Junction Proteins

(2009) Elsa Regan-Klapisz et al.   MOLECULAR BIOLOGY OF THE CELL

The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

(2009) Kevin J Whitehead et al.   NATURE MEDICINE

Lung endothelial barrier protection by iloprost in the 2-hit models of ventilator-induced lung injury (VILI) involves inhibition of Rho signaling

(2009) Anna A. Birukova et al.   Translational Research

Widely Conserved Signaling Pathways in the Establishment of Cell Polarity

(2009) L. M. McCaffrey et al.   Cold Spring Harbor Perspectives in Biology

Remodeling Epithelial Cell Organization: Transitions Between Front-Rear and Apical-Basal Polarity

(2009) W. J. Nelson   Cold Spring Harbor Perspectives in Biology

Endocytic Trafficking of Rac Is Required for the Spatial Restriction of Signaling in Cell Migration

(2008) Andrea Palamidessi et al.   CELL

Regulation of cell polarity during epithelial morphogenesis

(2008) Fernando Martin-Belmonte et al.   CURRENT OPINION IN CELL BIOLOGY

Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling

(2008) W. Koh et al.   JOURNAL OF CELL SCIENCE

The role of adherens junctions and VE-cadherin in the control of vascular permeability

(2008) E. Dejana et al.   JOURNAL OF CELL SCIENCE

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5

(2008) Andrea Taddei et al.   NATURE CELL BIOLOGY

Crosstalk between small GTPases and polarity proteins in cell polarization

(2008) Sandra Iden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY