A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and down-regulation

β2-Adrenergic Receptor Lysosomal Trafficking Is Regulated by Ubiquitination of Lysyl Residues in Two Distinct Receptor Domains

(2011) Kunhong Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay

(2011) Christof Fellmann et al.   MOLECULAR CELL

New perspectives regarding β2-adrenoceptor ligands in the treatment of asthma

(2010) JKL Walker et al.   BRITISH JOURNAL OF PHARMACOLOGY

Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the β2-adrenergic receptor

(2010) Joseph F Nabhan et al.   EMBO REPORTS

Function-based gene identification using enzymatically generated normalized shRNA library and massive parallel sequencing

(2010) M. Shtutman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation

(2009) Philip R. Cooper et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Rab11 regulates the recycling of the β2-adrenergic receptor through a direct interaction

(2008) Audrey Parent et al.   BIOCHEMICAL JOURNAL

Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7

(2008) Narendra Wajapeyee et al.   CELL

An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer

(2008) Lars Zender et al.   CELL

Clinical predictors and outcomes of consistent bronchodilator response in the childhood asthma management program

(2008) Sunita Sharma et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Nedd4 Mediates Agonist-dependent Ubiquitination, Lysosomal Targeting, and Degradation of the β2-Adrenergic Receptor

(2008) Sudha K. Shenoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol-dependent Separation of the β2-Adrenergic Receptor from Its Partners Determines Signaling Efficacy

(2008) Stéphanie M. Pontier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer Proliferation Gene Discovery Through Functional Genomics

(2008) M. R. Schlabach et al.   SCIENCE

Regulation of GPCRs by Endocytic Membrane Trafficking and Its Potential Implications

(2007) Aylin C. Hanyaloglu et al.   Annual Review of Pharmacology and Toxicology