Retinoic acid signaling and neuronal differentiation

Active repression by RAR  signaling is required for vertebrate axial elongation

(2014) A. Janesick et al.   DEVELOPMENT

Dedifferentiation of Neurons Precedes Tumor Formation in lola Mutants

(2014) Tony D. Southall et al.   DEVELOPMENTAL CELL

aPKC Phosphorylates p27Xic1, Providing a Mechanistic Link between Apicobasal Polarity and Cell-Cycle Control

(2014) Nitin Sabherwal et al.   DEVELOPMENTAL CELL

Dedifferentiation and reprogramming: origins of cancer stem cells

(2014) D. Friedmann-Morvinski et al.   EMBO REPORTS

A Mollusk Retinoic Acid Receptor (RAR) Ortholog Sheds Light on the Evolution of Ligand Binding

(2014) Juliana Gutierrez-Mazariegos et al.   ENDOCRINOLOGY

AP-1c-Jun/FosBmediates xFoxD5b expression in Xenopus early developmental neurogenesis

(2014) Jaeho Yoon et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Cloning and characterization of the retinoic acid receptor-like protein in the rock shell, Thais clavigera

(2013) Hiroshi Urushitani et al.   AQUATIC TOXICOLOGY

NumbL is essential for Xenopus primary neurogenesis

(2013) Frank Nieber et al.   BMC DEVELOPMENTAL BIOLOGY

Differentiation therapy for IDH1/2 mutant malignancies

(2013) Francine E Garrett-Bakelman et al.   CELL RESEARCH

The BAF Complex Interacts with Pax6 in Adult Neural Progenitors to Establish a Neurogenic Cross-Regulatory Transcriptional Network

(2013) Jovica Ninkovic et al.   Cell Stem Cell

Effect of All-Trans Retinoic Acid on the Differentiation of U87 Glioma Stem/Progenitor Cells

(2013) Zhe Shi et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Retinoid Acid Specifies Neuronal Identity through Graded Expression of Ascl1

(2013) John Jacob et al.   CURRENT BIOLOGY

ERF and ETV3L are retinoic acid-inducible repressors required for primary neurogenesis

(2013) A. Janesick et al.   DEVELOPMENT

Retinoic acid receptors’ expression and function during zebrafish early development

(2013) Eva Oliveira et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Control of cell cycle transcription during G1 and S phases

(2013) Cosetta Bertoli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeting Neuroblastoma Stem Cells with Retinoic Acid and Proteasome Inhibitor

(2013) Barbara Hämmerle et al.   PLoS One

An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

(2013) D. Rohle et al.   SCIENCE

The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors

(2013) Manuel Eguren et al.   Nature Communications

Calfacilitin is a calcium channel modulator essential for initiation of neural plate development

(2013) Costis Papanayotou et al.   Nature Communications

Antagonism between Retinoic Acid and Fibroblast Growth Factor Signaling during Limb Development

(2013) Thomas J. Cunningham et al.   Cell Reports

On the ‘Discovery’ of Vitamin A

(2012) Richard D. Semba   ANNALS OF NUTRITION AND METABOLISM

Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

(2012) Sarah Schwitalla et al.   CELL

EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear

(2012) M. Ahmed et al.   DEVELOPMENT

Retinoic acid signalling during development

(2012) M. Rhinn et al.   DEVELOPMENT

Identification of Retinol Binding Protein 1 Promoter Hypermethylation in Isocitrate Dehydrogenase 1 and 2 Mutant Gliomas

(2012) Arthur P. Chou et al.   JNCI-Journal of the National Cancer Institute

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

(2012) Sevin Turcan et al.   NATURE

Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

(2012) Johan H. van Es et al.   NATURE CELL BIOLOGY

Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice

(2012) D. Friedmann-Morvinski et al.   SCIENCE

Transcriptional Elongation Factor Elongin A Regulates Retinoic Acid-Induced Gene Expression during Neuronal Differentiation

(2012) Takashi Yasukawa et al.   Cell Reports

Lim homeobox genes in the Ctenophore Mnemiopsis leidyi: the evolution of neural cell type specification

(2012) David K Simmons et al.   EvoDevo

The calcium: an early signal that initiates the formation of the nervous system during embryogenesis

(2012) Catherine Leclerc et al.   Frontiers in Molecular Neuroscience

Identification of Stage-Specific Gene Expression Signatures in Response to Retinoic Acid during the Neural Differentiation of Mouse Embryonic Stem Cells

(2012) Hiromi Akanuma et al.   Frontiers in Genetics

Aberrant Expression of Retinoic Acid Signaling Molecules Influences Patient Survival in Astrocytic Gliomas

(2011) Benito Campos et al.   AMERICAN JOURNAL OF PATHOLOGY

Cloning and characterization of retinoid X receptor (RXR) isoforms in the rock shell, Thais clavigera

(2011) Hiroshi Urushitani et al.   AQUATIC TOXICOLOGY

The response of early neural genes to FGF signaling or inhibition of BMP indicate the absence of a conserved neural induction module

(2011) Crystal D Rogers et al.   BMC DEVELOPMENTAL BIOLOGY

Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma

(2011) Chong Liu et al.   CELL

Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis

(2011) F. Ali et al.   DEVELOPMENT

A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets

(2011) D. S. Castro et al.   GENES & DEVELOPMENT

New insights on ctenophore neural anatomy: Immunofluorescence study in Pleurobrachia pileus (Müller, 1776)

(2011) Muriel Jager et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

Differential Retinoic Acid Signaling in Tumors of Long- and Short-term Glioblastoma Survivors

(2011) Sebastian Barbus et al.   JNCI-Journal of the National Cancer Institute

Role of BMP, FGF, Calcium Signaling, and Zic Proteins in Vertebrate Neuroectodermal Differentiation

(2011) Jun Aruga et al.   NEUROCHEMICAL RESEARCH

Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition

(2011) M Ying et al.   ONCOGENE

Regional Differentiation of Retinoic Acid-Induced Human Pluripotent Embryonic Carcinoma Stem Cell Neurons

(2011) Dennis E. Coyle et al.   PLoS One

Primordial neurosecretory apparatus identified in the choanoflagellate Monosiga brevicollis

(2011) P. Burkhardt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA and DNA methylation alterations mediating retinoic acid induced neuroblastoma cell differentiation

(2011) Raymond L. Stallings et al.   SEMINARS IN CANCER BIOLOGY

Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

(2010) Houtan Noushmehr et al.   CANCER CELL

MicroRNA Mediates DNA Demethylation Events Triggered by Retinoic Acid during Neuroblastoma Cell Differentiation

(2010) S. Das et al.   CANCER RESEARCH

NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome

(2010) Michael Hölzel et al.   CELL

Retinoic acid treatment and cell aggregation independently regulate alternative splicing in P19 cells during neural differentiation

(2010) AHM Khurshid Alam et al.   CELL BIOLOGY INTERNATIONAL

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo

(2010) J.-W. Lim et al.   DEVELOPMENT

FGF signalling: diverse roles during early vertebrate embryogenesis

(2010) K. Dorey et al.   DEVELOPMENT

Steps towards a centralized nervous system in basal bilaterians: Insights from neurogenesis of the acoel Symsagittifera roscoffensis

(2010) Henrike Semmler et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Microarray identification of novel downstream targets of FoxD4L1/D5, a critical component of the neural ectodermal transcriptional network

(2010) Bo Yan et al.   DEVELOPMENTAL DYNAMICS

MicroRNAs-10a and -10b Contribute to Retinoic Acid-induced Differentiation of Neuroblastoma Cells and Target the Alternative Splicing Regulatory Factor SFRS1 (SF2/ASF)

(2010) Salvador Meseguer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Origin and evolution of the ligand-binding ability of nuclear receptors

(2010) Gabriel V. Markov et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Neuronatin Promotes Neural Lineage in ESCs via Ca2+ Signaling

(2010) Hsuan-Hwai Lin et al.   STEM CELLS

Cell cycle control of mammalian neural stem cells: putting a speed limit on G1

(2010) Paolo Salomoni et al.   TRENDS IN CELL BIOLOGY

Oikopleura dioicaAlcohol Dehydrogenase Class 3 Provides New Insights into the Evolution of Retinoic Acid Synthesis in Chordates

(2010) Cristian Cañestro et al.   ZOOLOGICAL SCIENCE

Cellular Strategies of Axonal Pathfinding

(2010) J. Raper et al.   Cold Spring Harbor Perspectives in Biology

Neural induction and factors that stabilize a neural fate

(2009) Crystal D. Rogers et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

ATP7A is a novel target of retinoic acid receptor β2 in neuroblastoma cells

(2009) A Bohlken et al.   BRITISH JOURNAL OF CANCER

ZNF423 Is Critically Required for Retinoic Acid-Induced Differentiation and Is a Marker of Neuroblastoma Outcome

(2009) Sidong Huang et al.   CANCER CELL

Retinoic Acid from the Meninges Regulates Cortical Neuron Generation

(2009) Julie A. Siegenthaler et al.   CELL

Functional decreases in P2X7 receptors are associated with retinoic acid-induced neuronal differentiation of Neuro-2a neuroblastoma cells

(2009) Pei-Yu Wu et al.   CELLULAR SIGNALLING

MicroRNA Involvement in the Pathogenesis of Neuroblastoma: Potential for MicroRNA Mediated Therapeutics

(2009) R. Stallings   CURRENT PHARMACEUTICAL DESIGN

FoxD5 mediates anterior–posterior polarity through upstream modulator Fgf signaling during zebrafish somitogenesis

(2009) Hung-Chieh Lee et al.   DEVELOPMENTAL BIOLOGY

Origins of neurogenesis, a cnidarian view

(2009) Brigitte Galliot et al.   DEVELOPMENTAL BIOLOGY

BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus

(2009) Andrea E. Wills et al.   DEVELOPMENTAL BIOLOGY

Notch signaling downstream offoxD5promotes neural ectodermal transcription factors that inhibit neural differentiation

(2009) Bo Yan et al.   DEVELOPMENTAL DYNAMICS

The retinoic acid machinery in invertebrates: Ancestral elements and vertebrate innovations

(2009) Ricard Albalat   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Characterisation of the Fibroblast Growth Factor Dependent Transcriptome in Early Development

(2009) Peter A. Branney et al.   PLoS One

BMP inhibition initiates neural induction via FGF signaling and Zic genes

(2009) L. Marchal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FGF-activated calcium channels control neural gene expression in Xenopus

(2008) Karen W. Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Identification of Aldh1a, Cyp26 and RAR orthologs in protostomes pushes back the retinoic acid genetic machinery in evolutionary time to the bilaterian ancestor

(2008) Ricard Albalat et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Retinoic acid signaling in development: Tissue-specific functions and evolutionary origins

(2008) Florent Campo-Paysaa et al.   GENESIS

Detection of Endogenous Retinoids in the Molluscan CNS and Characterization of the Trophic and Tropic Actions of 9-cis Retinoic Acid on Isolated Neurons

(2008) J. M. Dmetrichuk et al.   JOURNAL OF NEUROSCIENCE

Hoxa1 is required for the retinoic acid-induced differentiation of embryonic stem cells into neurons

(2008) Eduardo Martinez-Ceballos et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Xenopus Sox3 activates sox2 and geminin and indirectly represses Xvent2 expression to induce neural progenitor formation at the expense of non-neural ectodermal derivatives

(2008) Crystal D. Rogers et al.   MECHANISMS OF DEVELOPMENT

Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells

(2008) Fumitaka Osakada et al.   NATURE BIOTECHNOLOGY

Retinoic acid in development: towards an integrated view

(2008) Karen Niederreither et al.   NATURE REVIEWS GENETICS

Retinoic acid as cause of cell proliferation or cell growth inhibition depending on activation of one of two different nuclear receptors

(2008) George Wolf   NUTRITION REVIEWS

Retinoic acid downregulates Rae1 leading to APCCdh1 activation and neuroblastoma SH-SY5Y differentiation

(2008) J Cuende et al.   ONCOGENE

Calcium signalling during neural induction in Xenopus laevis embryos

(2008) M. Moreau et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Overcoming retinoic acid-resistance of mammary carcinomas by diverting retinoic acid from PPAR /  to RAR

(2008) T. T. Schug et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mechanism Regulating the Onset of Sox2 Expression in the Embryonic Neural Plate

(2008) Costis Papanayotou et al.   PLOS BIOLOGY

Gene expression profiling elucidates a specific role for RARγ in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells

(2007) Dan Su et al.   BIOCHEMICAL PHARMACOLOGY

Crystal Structure of E47−NeuroD1/Beta2 bHLH Domain−DNA Complex:  Heterodimer Selectivity and DNA Recognition†,‡

(2007) Antonella Longo et al.   BIOCHEMISTRY