Developments in high-speed countercurrent chromatography and its applications in the separation of terpenoids and saponins

Overcoming the equivalent-chain-length rule with pH-zone-refining countercurrent chromatography for the preparative separation of fatty acids

(2015) Michael Englert et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

High-speed counter-current chromatography coupled online to high performance liquid chromatography–diode array detector–mass spectrometry for purification, analysis and identification of target compounds from natural products

(2015) Xuejuan Liang et al.   JOURNAL OF CHROMATOGRAPHY A

Development of a method to screen and isolate potential xanthine oxidase inhibitors from Panax japlcus var via ultrafiltration liquid chromatography combined with counter-current chromatography

(2015) Sainan Li et al.   TALANTA

Terpenes and derivatives as a new perspective for pain treatment: a patent review

(2014) Adriana G Guimarães et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides

(2014) Mengshun Liu et al.   JOURNAL OF CHROMATOGRAPHY A

Separation of amaranthine-type betacyanins by ion-pair high-speed countercurrent chromatography

(2014) Gerold Jerz et al.   JOURNAL OF CHROMATOGRAPHY A

High-speed countercurrent chromatographic recovery and off-line electrospray ionization mass spectrometry profiling of bisdesmodic saponins from Saponaria officinalis possessing synergistic toxicity enhancing properties on targeted antitumor toxins

(2014) Mayank Thakur et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Counter-current chromatography for the separation of terpenoids: a comprehensive review with respect to the solvent systems employed

(2014) Krystyna Skalicka-Woźniak et al.   PHYTOCHEMISTRY REVIEWS

Preparative separation of conjugated linoleic acids (CLAs) from fermented Camellia oleifera Abel cake by β-cyclodextrin (β-CD) encapsulation using pH-zone-refining countercurrent chromatography

(2013) Guanglei Song et al.   FOOD CHEMISTRY

Preparative Purification of Morroniside and Loganin from Fructus corni by Combination of Macroporous Absorption Resin and HSCCC

(2013) L. Lui et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Purification of Two Triterpenoids from Schisandra chinensis by Macroporous Resin Combined with High-Speed Counter-Current Chromatography

(2013) L. Zhu et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Large-scale separation of alkaloids from Gelsemium elegans by pH-zone-refining counter-current chromatography with a new solvent system screening method

(2013) Lei Fang et al.   JOURNAL OF CHROMATOGRAPHY A

Application of pH-zone-refining countercurrent chromatography for the separation of indole alkaloids from Aspidosperma rigidum Rusby

(2013) Mariana N. Vieira et al.   JOURNAL OF CHROMATOGRAPHY A

ISOLATION OF FIVE GLYCOSIDES FROM THE BARKS OFILEX ROTUNDABY HIGH-SPEED COUNTER-CURRENT CHROMATOGRAPHY

(2013) Chun Wang et al.   JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES

Separation of chlorogenic acid and concentration of trace caffeic acid from natural products by pH-zone-refining countercurrent chromatography

(2013) Yuanyuan Lu et al.   JOURNAL OF SEPARATION SCIENCE

Saponins: the Potential Chemotherapeutic Agents in Pursuing New Anti-glioblastoma Drugs

(2013) Xiangrong Tian et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Combination of pressurized liquid extraction with countercurrent chromatography for systematical isolation of ginsenosides from Panax ginseng

(2013) Yuchi Zhang et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Separation and Purification of Two Isomeric Saponins from Albiziae Cortex by High-Speed Counter-Current Chromatography and Preparative High-Performance Liquid Chromatography

(2013) Lifeng Han et al.   SEPARATION SCIENCE AND TECHNOLOGY

New “hyphenated” CPC-HPLC-DAD-MS strategy for simultaneous isolation, analysis and identification of phytochemicals: application to xanthones from Garcinia mangostana

(2012) Thomas Michel et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Sequential determination of anionic-type detergents by complexation with methylene blue using dual high speed counter-current chromatography

(2012) Eiichi Kitazume et al.   JOURNAL OF CHROMATOGRAPHY A

FAST ISOLATION OF GINSENOSIDES Re AND Rg1 FROM THE ROOTS OFPANAX GINSENGBY HSCCC-ELSD COMBINED WITH MCI GEL CC GUIDED BY HPLC-MS

(2012) Fengqin Chen et al.   JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES

Separation of Two Cytotoxic Saponins from the Roots ofAdenophora triphyllavar.japonicaby High-speed Counter-current Chromatography

(2012) Minseok Kang et al.   PHYTOCHEMICAL ANALYSIS

Application of High-speed Countercurrent Chromatography-Evaporative Light Scattering Detection for the Separation of Seven Steroidal Saponins from Dioscorea villosa

(2012) Kee Dong Yoon et al.   PHYTOCHEMICAL ANALYSIS

Preparative isolation and purification of cuminaldehyde and p-menta-1,4-dien-7-al from the essential oil of Cuminum cyminum L. by high-speed counter-current chromatography

(2011) Qinqin Chen et al.   ANALYTICA CHIMICA ACTA

Preparative separation of alkaloids from Gelsemium elegans Benth. using pH-zone-refining counter-current chromatography

(2011) Yan-Ping Su et al.   JOURNAL OF CHROMATOGRAPHY A

On-line coupling of dynamic microwave-assisted extraction with high-speed counter-current chromatography for continuous isolation of nevadensin from Lyeicnotus pauciflorus Maxim.

(2011) Xing Tong et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

PREPARATIVE ISOLATION OF STEROIDAL SAPONINS FROM GARLIC (ALLIUM SATIVUML.) USING HIGH-SPEED COUNTER-CURRENT CHROMATOGRAPHY COUPLED WITH EVAPORATIVE LIGHT SCATTERING DETECTION

(2011) Qiang Ma et al.   JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES

Preparative separation of minor saponins from Platycodi Radix by high-speed counter-current chromatography

(2011) In J. Ha et al.   JOURNAL OF SEPARATION SCIENCE

Preparative separation of quaternary ammonium alkaloids from Corydalis yanhusuo W. T. Wang by pH-zone-refining counter-current chromatography

(2011) Qing Yu et al.   JOURNAL OF SEPARATION SCIENCE

Preparative separation of atropine and scopolamine from Daturae metelis Flos using pH-zone-refining counter-current chromatography with counter-rotation and dual-mode elution procedure

(2011) Yutong He et al.   JOURNAL OF SEPARATION SCIENCE

Development of a rapid and convenient method to separate eight ginsenosides from Panax ginseng by high-speed counter-current chromatography coupled with evaporative light scattering detection

(2011) Omer Shehzad et al.   JOURNAL OF SEPARATION SCIENCE

Target-guided separation of Bougainvillea glabra betacyanins by direct coupling of preparative ion-pair high-speed countercurrent chromatography and electrospray ionization mass-spectrometry

(2010) Gerold Jerz et al.   JOURNAL OF CHROMATOGRAPHY A

Preparative isolation and purification of ginsenosides Rf, Re, Rd and Rb1 from the roots of Panax ginseng with a salt/containing solvent system and flow step-gradient by high performance counter-current chromatography coupled with an evaporative light scattering detector

(2010) Xiaocheng Qi et al.   JOURNAL OF CHROMATOGRAPHY A

Preparative separation of isoquinoline alkaloids from Stephania yunnanensis by pH-zone-refining counter-current chromatography

(2010) Ruilin Hu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Preparative separation of alkaloids from Nelumbo nucifera leaves by conventional and pH-zone-refining counter-current chromatography

(2010) Zheng Zhenjia et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Panax notoginseng saponins promotes proliferation and osteogenic differentiation of rat bone marrow stromal cells

(2010) Xue-dong Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

SEPARATION AND PURIFICATION OF TRITERPENE SAPONINS FROM ROOTS OFRADIX PHYTOLACCAEBY HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY COUPLED WITH EVAPORATIVE LIGHT SCATTERING DETECTION

(2010) Jie Ma et al.   JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES

Sesquiterpenes fromOplopanax horridus

(2010) Taichi Inui et al.   JOURNAL OF NATURAL PRODUCTS

Preparative separation of alkaloids fromNelumbo nuciferaGaertn by pH-zone-refining counter-current chromatography

(2010) Xiao Wang et al.   JOURNAL OF SEPARATION SCIENCE

Quick identification of apoptosis inducer from Isodon eriocalyx by a drug discovery platform composed of analytical high-speed counter-current chromatography and the fluorescence-based caspase-3 biosensor detection

(2010) Quan-Bin Han et al.   TALANTA

Isolation and tandem mass fragmentations of an anti-inflammatory compound from Aralia elata

(2009) Ju Hyeon Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Isolation of chemical constituents from Daphne odora var. Margirmt by high-speed counter-current chromatography

(2009) R. J. Chen et al.   CHEMISTRY OF NATURAL COMPOUNDS

An Economical Method for Isolation of Dioscin from Dioscorea nipponica Makino by HSCCC Coupled with ELSD, and a Computer-Aided UNIFAC Mathematical Model

(2009) Lian-Hong Yin et al.   CHROMATOGRAPHIA

Isolation and Purification of Ginsenosides from Plant Extract of Panax quinquefolium L. by High Performance Centrifugal Partition Chromatography Coupled with ELSD

(2009) Jing Wang et al.   CHROMATOGRAPHIA

Use of pH-Zone Refining Countercurrent Chromatography for Preparative Separation of Fangchinoline and Tetrandrine from Stephania tetrandra

(2009) Zhang Lijin et al.   CHROMATOGRAPHIA

Isolation and purification of nootkatone from the essential oil of fruits of Alpinia oxyphylla Miquel by high-speed counter-current chromatography

(2009) Jianchun Xie et al.   FOOD CHEMISTRY

Supercritical fluid extraction of Coriandrum sativum and subsequent separation of isocoumarins by high-speed counter-current chromatography

(2009) Qing Chen et al.   FOOD CHEMISTRY

Isolation of secondary metabolites from Hortia oreadica (Rutaceae) leaves through high-speed counter-current chromatography

(2009) Vanessa Gisele Pasqualotto Severino et al.   JOURNAL OF CHROMATOGRAPHY A

Separation of polar betalain pigments from cacti fruits of Hylocereus polyrhizus by ion-pair high-speed countercurrent chromatography

(2009) Sławomir Wybraniec et al.   JOURNAL OF CHROMATOGRAPHY A

An application of high-speed counter-current chromatography coupled with electrospray ionization mass spectrometry for separation and online identification of coumarins from Peucedanum praeruptorum Dunn

(2009) Zhiguo Hou et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Isolation of coffee diterpenes by means of high-speed countercurrent chromatography

(2009) Heike Scharnhop et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

An approach to on-line electrospray mass spectrometric detection of polypeptide antibiotics of enramycin for high-speed counter-current chromatographic separation

(2009) Koichi Inoue et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Preparative isolation of six major saponins from Platycodi Radix by high-speed counter-current chromatography

(2009) Young Wan Ha et al.   PHYTOCHEMICAL ANALYSIS

Development of a Fast and Convenient Method for the Isolation of Triterpene Saponins fromActaea racemosaby High-speed Countercurrent Chromatography Coupled with Evaporative Light Scattering Detection

(2009) Serhat Cicek et al.   PLANTA MEDICA

Supercritical fluid extraction of cordycepin and adenosine from Cordyceps kyushuensis and purification by high-speed counter-current chromatography

(2009) Jian Ya Ling et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Preparative isolation and purification of steviol glycosides from Stevia rebaudiana Bertoni using high-speed counter-current chromatography

(2009) Xin-Yi Huang et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Separation and Purification of α-Cyperone fromCyperus rotunduswith Supercritical Fluid Extraction and High-Speed Counter-Current Chromatography

(2009) Xingang Shi et al.   SEPARATION SCIENCE AND TECHNOLOGY

Hyphenated HSCCC–DPPH· for Rapid Preparative Isolation and Screening of Antioxidants from Selaginella moellendorffii

(2008) Shuyun Shi et al.   CHROMATOGRAPHIA

Separation of betalains from berries of Phytolacca americana by ion-pair high-speed counter-current chromatography

(2008) Gerold Jerz et al.   JOURNAL OF CHROMATOGRAPHY A

Preparative separation of isomeric caffeoylquinic acids from Flos Lonicerae by pH-zone-refining counter-current chromatography

(2008) Shengqiang Tong et al.   JOURNAL OF CHROMATOGRAPHY A

Flow rate gradient high-speed counter-current chromatography separation of five diterpenoids from Triperygium wilfordii and scale-up

(2008) Aihua Peng et al.   JOURNAL OF CHROMATOGRAPHY A

Separation of epigallocatechin and flavonoids from Hypericum perforatum L. by high-speed counter-current chromatography and preparative high-performance liquid chromatography

(2008) Yun Wei et al.   JOURNAL OF CHROMATOGRAPHY A

Application of preparative high-speed counter-current chromatography/preparative high-performance liquid chromatography mode in rapid separation of saponins

(2008) Shun Yao et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Purification of Eremophilane‐Type Sesquiterpenes fromLigularia atroviolaceaby High Speed Countercurrent Chromatography

(2008) Shu Yun Shi et al.   JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES

Preparative Separation and Purification of β-Caryophyllene from Leaf Oil of Vitex negundo L. var. heterophylla (Franch.) Rehd. by High Speed Countercurrent Chromatography

(2008) Jianchun Xie et al.   JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES

Separation and purification of harmine and harmaline fromPeganum harmalausing pH-zone-refining counter-current chromatography

(2008) Xiao Wang et al.   JOURNAL OF SEPARATION SCIENCE

Preparative isolation of pseudolaric acids A and B, and their glucosides from the root bark ofPseudolarix kaempferiusing high-speed counter-current chromatography

(2008) Quan-Bin Han et al.   JOURNAL OF SEPARATION SCIENCE

Application of analytical and preparative high-speed counter-current chromatography for the separation ofZ-ligustilide from a crude extract ofAngelica sinensis

(2008) Xiao Wang et al.   PHYTOCHEMICAL ANALYSIS

Isolation of Limonoids from seeds ofCarapa guianensisAublet (Meliaceae) by high-speed countercurrent chromatography

(2008) Vagner Pereira da Silva et al.   PHYTOCHEMICAL ANALYSIS

Preparative isolation of six platycosides from Platycodi Radix by high-speed counter-current chromatography with evaporative light scattering detection

(2008) YW Ha et al.   PLANTA MEDICA

Isolation of ursolic acid from apple peels by high speed counter-current chromatography

(2007) Rosa T.S. Frighetto et al.   FOOD CHEMISTRY

Preparative isolation and purification of chemical components fromAconitum coreanum by high-speed counter-current chromatography coupled with evaporative light scattering detection

(2007) Qingfa Tang et al.   PHYTOCHEMICAL ANALYSIS