Single-cell RNA sequence presents atlas analysis for chondrocytes in the talus and reveals the potential mechanism in coping with mechanical stress

Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes

(2022) Nicole Bell et al.   BONE

COMP and TSP-4: Functional Roles in Articular Cartilage and Relevance in Osteoarthritis

(2021) Kathrin Maly et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Vorinostat ameliorates IL‐1α‐induced reduction of type II collagen by inhibiting the expression of ELF3 in chondrocytes

(2021) Xudong Miao et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Comparison of the major cell populations among osteoarthritis, Kashin–Beck disease and healthy chondrocytes by single-cell RNA-seq analysis

(2021) Xi Wang et al.   Cell Death & Disease

Instability and excessive mechanical loading mediate subchondral bone changes to induce osteoarthritis

(2020) Jianxi Zhu et al.   Annals of Translational Medicine

TIMP3/TGF‑β1 axis regulates mechanical loading‑induced chondrocyte degeneration and angiogenesis

(2020) De‑Lai Zhao et al.   Molecular Medicine Reports

FN1 promotes chondrocyte differentiation and collagen production via TGF-β/PI3K/Akt pathway in mice with femoral fracture

(2020) Heli Zhang et al.   GENE

Comparative profiling of chondrogenic differentiation of mesenchymal stem cells (MSCs) driven by two different growth factors

(2019) Xintang Zhan et al.   CELL BIOCHEMISTRY AND FUNCTION

Nuclear action of FGF members in endocrine-related tissues and cancer: Interplay with steroid receptor pathways

(2019) Virginia Figueroa et al.   STEROIDS

Single-cell RNA-seq analysis reveals the progression of human osteoarthritis

(2018) Quanbo Ji et al.   ANNALS OF THE RHEUMATIC DISEASES

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

(2017) Ok Hee Jeon et al.   NATURE MEDICINE

Cellular senescence in aging and osteoarthritis

(2016) Wei Seong Toh et al.   Acta Orthopaedica

ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity

(2016) Miguel Otero et al.   CONNECTIVE TISSUE RESEARCH

Structural and mechanical properties of the proliferative zone of the developing murine growth plate cartilage assessed by atomic force microscopy

(2016) Carina Prein et al.   MATRIX BIOLOGY

Changes in the osteochondral unit during osteoarthritis: structure, function and cartilage–bone crosstalk

(2016) Steven R. Goldring et al.   Nature Reviews Rheumatology

Mechanical Forces Induce Changes in VEGF and VEGFR-1/sFlt-1 Expression in Human Chondrocytes

(2014) Rainer Beckmann et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Involvement of Angiopoietin-like 4 in Matrix Remodeling during Chondrogenic Differentiation of Mesenchymal Stem Cells

(2014) Marc Mathieu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The disease modifying osteoarthritis drug diacerein is able to antagonize pro inflammatory state of chondrocytes under mild mechanical stimuli

(2014) B. Steinecker-Frohnwieser et al.   OSTEOARTHRITIS AND CARTILAGE

Functional biomaterials for cartilage regeneration

(2012) Zigang Ge et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Effects of Exposure to a DNA Damaging Agent on the Hypoxia Inducible Factors in Organogenesis Stage Mouse Limbs

(2012) Chunwei Huang et al.   PLoS One

Importance of syndecan-4 and syndecan -2 in osteoblast cell adhesion and survival mediated by a tissue transglutaminase−fibronectin complex

(2010) Z. Wang et al.   EXPERIMENTAL CELL RESEARCH

The relation between geometry and function of the ankle joint complex: a biomechanical review

(2010) Roeland P. Kleipool et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Articular cartilage: structure, injuries and review of management

(2008) A. M. Bhosale et al.   BRITISH MEDICAL BULLETIN

Metal Ions-Stimulated Iron Oxidation in Hydroxylases Facilitates Stabilization of HIF-1α Protein

(2008) Monika Kaczmarek et al.   TOXICOLOGICAL SCIENCES