ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity

Hydroxymethylation is uniquely distributed within term placenta, and is associated with gene expression

(2016) Benjamin B. Green et al.   FASEB JOURNAL

Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis

(2016) E.W. Bradley et al.   OSTEOARTHRITIS AND CARTILAGE

Stable 5-Hydroxymethylcytosine (5hmC) Acquisition Marks Gene Activation During Chondrogenic Differentiation

(2015) Sarah EB Taylor et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Epigenetic regulation of interleukin-8, an inflammatory chemokine, in osteoarthritis

(2015) A. Takahashi et al.   OSTEOARTHRITIS AND CARTILAGE

DNA methylation regulates sclerostin (SOST) expression in osteoarthritic chondrocytes by bone morphogenetic protein 2 (BMP-2) induced changes in Smads binding affinity to the CpG region of SOST promoter

(2015) Ioanna Papathanasiou et al.   ARTHRITIS RESEARCH & THERAPY

CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383

(2014) Louise N. Reynard et al.   HUMAN GENETICS

Epigenetic differences in human cartilage between mild and severe OA

(2014) Florentine C. Moazedi-Fuerst et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Association of Reduced Type IX Collagen Gene Expression in Human Osteoarthritic Chondrocytes With Epigenetic Silencing by DNA Hypermethylation

(2014) Kei Imagawa et al.   Arthritis & Rheumatology

Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Cartilage

(2014) Matlock A. Jeffries et al.   Arthritis & Rheumatology

Characterization of the Cartilage DNA Methylome in Knee and Hip Osteoarthritis

(2014) Michael D. Rushton et al.   Arthritis & Rheumatology

Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients

(2013) Juan Fernández-Tajes et al.   ANNALS OF THE RHEUMATIC DISEASES

Chromatin: Receiver and Quarterback for Cellular Signals

(2013) David G. Johnson et al.   CELL

Regulated Transcription of Human Matrix Metalloproteinase 13 (MMP13) and Interleukin-1β (IL1B) Genes in Chondrocytes Depends on Methylation of Specific Proximal Promoter CpG Sites

(2013) Ko Hashimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TET enzymes, TDG and the dynamics of DNA demethylation

(2013) Rahul M. Kohli et al.   NATURE

Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes

(2012) María C. de Andrés et al.   ARTHRITIS AND RHEUMATISM

Maintenance of DNA methylation: Dnmt3b joins the dance

(2012) Emma L. Walton et al.   Epigenetics

cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis

(2012) Catherine Bui et al.   FASEB JOURNAL

Changes in the epigenetic status of theSOX-9promoter in human osteoarthritic cartilage

(2012) Kyung-Il Kim et al.   JOURNAL OF BONE AND MINERAL RESEARCH

DNA Methylation and Its Basic Function

(2012) Lisa D Moore et al.   NEUROPSYCHOPHARMACOLOGY

Epigenetic mechanisms in cartilage and osteoarthritis: DNA methylation, histone modifications and microRNAs

(2012) M.J. Barter et al.   OSTEOARTHRITIS AND CARTILAGE

CG methylation

(2012) Charles Vinson et al.   Epigenomics

The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes – Implications for osteoarthritis

(2011) Kei Imagawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

E74-like Factor 3 (ELF3) Impacts on Matrix Metalloproteinase 13 (MMP13) Transcriptional Control in Articular Chondrocytes under Proinflammatory Stress

(2011) Miguel Otero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis

(2011) Mary B. Goldring et al.   TRENDS IN MOLECULAR MEDICINE

Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease

(2010) J. L. Scott et al.   ANNALS OF THE RHEUMATIC DISEASES

CpG methylation of half-CRE sequences creates C/EBP  binding sites that activate some tissue-specific genes

(2010) V. Rishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA demethylation at specific CpG sites in theIL1Bpromoter in response to inflammatory cytokines in human articular chondrocytes

(2009) Ko Hashimoto et al.   ARTHRITIS AND RHEUMATISM

Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter

(2008) Peter Zimmermann et al.   ARTHRITIS AND RHEUMATISM

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation

(2008) Jing Wu et al.   CELL RESEARCH

Smad3 activates the Sox9-dependent transcription on chromatin

(2008) Takayuki Furumatsu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage

(2008) Marco A. da Silva et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

DNA methylation is not responsible for p21WAF1/CIP1 down-regulation in osteoarthritic chondrocytes

(2008) S. Sesselmann et al.   OSTEOARTHRITIS AND CARTILAGE

ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes

(2007) Haibing Peng et al.   JOURNAL OF CELLULAR PHYSIOLOGY