Near-infrared fluorescence lifetime imaging of amyloid-β aggregates and tau fibrils through the intact skull of mice

Advances in Brain Amyloid Imaging

(2021) Natasha Krishnadas et al.   SEMINARS IN NUCLEAR MEDICINE

ZW800‐PEG: A Renal Clearable Zwitterionic Near‐Infrared Fluorophore for Potential Clinical Translation

(2021) Chengeng Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Detection of cerebral tauopathy in P301L mice using high-resolution large-field multifocal illumination fluorescence microscopy

(2020) Ruiqing Ni et al.   Biomedical Optics Express

High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer’s and Non-Alzheimer’s Disease Tauopathies

(2020) Kenji Tagai et al.   NEURON

In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

(2019) Maria Calvo-Rodriguez et al.   Acta Neuropathologica Communications

Imaging tau and amyloid-β proteinopathies in Alzheimer disease and other conditions

(2018) Victor L. Villemagne et al.   Nature Reviews Neurology

In Vivo Near-Infrared Two-Photon Imaging of Amyloid Plaques in Deep Brain of Alzheimer’s Disease Mouse Model

(2018) Congping Chen et al.   ACS Chemical Neuroscience

SPECT and PET imaging in Alzheimer’s disease

(2018) Varvara Valotassiou et al.   ANNALS OF NUCLEAR MEDICINE

Three-photon imaging of mouse brain structure and function through the intact skull

(2018) Tianyu Wang et al.   NATURE METHODS

Near-Infrared Fluorescent Proteins: Multiplexing and Optogenetics across Scales

(2018) Daria M. Shcherbakova et al.   TRENDS IN BIOTECHNOLOGY

Oxalate-curcumin–based probe for micro- and macroimaging of reactive oxygen species in Alzheimer’s disease

(2017) Jian Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluoro-substituted cyanine for reliable in vivo labelling of amyloid-β oligomers and neuroprotection against amyloid-β induced toxicity

(2017) Yinhui Li et al.   Chemical Science

Near-infrared fluorophores for biomedical imaging

(2017) Guosong Hong et al.   Nature Biomedical Engineering

A Smart Near-Infrared Fluorescence Probe for Selective Detection of Tau Fibrils in Alzheimer’s Disease

(2016) Yujin Seo et al.   ACS Chemical Neuroscience

Amyloid-β Deposits Target Efficient Near-Infrared Fluorescent Probes: Synthesis, in Vitro Evaluation, and in Vivo Imaging

(2016) Hualong Fu et al.   ANALYTICAL CHEMISTRY

A quadrupolar two-photon fluorescent probe for in vivo imaging of amyloid-β plaques

(2016) Cheol Ho Heo et al.   Chemical Science

A Palette of Fluorescent Thiophene-Based Ligands for the Identification of Protein Aggregates

(2015) Hamid Shirani et al.   CHEMISTRY-A EUROPEAN JOURNAL

Transmission in near-infrared optical windows for deep brain imaging

(2015) Lingyan Shi et al.   Journal of Biophotonics

Two-Photon Absorbing Dyes with Minimal Autofluorescence in Tissue Imaging: Application to in Vivo Imaging of Amyloid-β Plaques with a Negligible Background Signal

(2015) Dokyoung Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Fluorescent Probe for Detection of Aβ Oligomers

(2015) Chai Lean Teoh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A curcumin-based molecular probe for near-infrared fluorescence imaging of tau fibrils in Alzheimer's disease

(2015) Kwang-su Park et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease

(2015) Xueli Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Near-infrared fluorescent probes for imaging of amyloid plaques in Alzheimer׳s disease

(2015) Hongjuan Tong et al.   Acta Pharmaceutica Sinica B

PET/SPECT imaging agents for neurodegenerative diseases

(2014) Lin Zhu et al.   CHEMICAL SOCIETY REVIEWS

Transporters at CNS Barrier Sites: Obstacles or Opportunities for Drug Delivery?

(2014) Lucy Sanchez-Covarrubias et al.   CURRENT PHARMACEUTICAL DESIGN

Smart Near-Infrared Fluorescence Probes with Donor–Acceptor Structure for in Vivo Detection of β-Amyloid Deposits

(2014) Mengchao Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Age-associated dysregulation of microglial activation is coupled with enhanced blood-brain barrier permeability and pathology in APP/PS1 mice

(2014) Aedín M. Minogue et al.   NEUROBIOLOGY OF AGING

Central C–C bonding increases optical and chemical stability of NIR fluorophores

(2014) Hoon Hyun et al.   RSC Advances

Design and Synthesis of Curcumin Analogues for in Vivo Fluorescence Imaging and Inhibiting Copper-Induced Cross-Linking of Amyloid Beta Species in Alzheimer’s Disease

(2013) Xueli Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted zwitterionic near-infrared fluorophores for improved optical imaging

(2013) Hak Soo Choi et al.   NATURE BIOTECHNOLOGY

PiB-Conjugated, Metal-Based Imaging Probes: Multimodal Approaches for the Visualization of β-Amyloid Plaques

(2013) André F. Martins et al.   ACS Medicinal Chemistry Letters

Development of Positron Emission Tomography β-Amyloid Plaque Imaging Agents

(2012) Chester A. Mathis et al.   SEMINARS IN NUCLEAR MEDICINE

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Synthesis and In Vivo Fate of Zwitterionic Near-Infrared Fluorophores

(2011) Hak Soo Choi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Magnetic Resonance Imaging of Amyloid Plaques in Transgenic Mouse Models of Alzheimers Disease

(2011) Ryan Chamberlain et al.   Current Medical Imaging Reviews

Lifetime-based tomographic multiplexing

(2010) Scott B. Raymond et al.   JOURNAL OF BIOMEDICAL OPTICS

Full-field time-resolved fluorescence tomography of small animals

(2010) Vivek Venugopal et al.   OPTICS LETTERS

Characteristics of compounds that cross the blood-brain barrier

(2009) William A Banks   BMC Neurology

Optical visualization of Alzheimer’s pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation

(2009) Alex C. Kwan et al.   OPTICS EXPRESS

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON