Exploiting a conjugative endogenous CRISPR-Cas3 system to tackle multidrug-resistant Klebsiella pneumoniae

Cracking the Challenge of Antimicrobial Drug Resistance with CRISPR/Cas9, Nanotechnology and Other Strategies in ESKAPE Pathogens

(2021) Tanzeel Zohra et al.   Microorganisms

Mobilization of the nonconjugative virulence plasmid from hypervirulent Klebsiella pneumoniae

(2021) Yanping Xu et al.   Genome Medicine

Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infections

(2021) Yuye Wu et al.   JOURNAL OF NANOBIOTECHNOLOGY

Carbapenem Resistance-Encoding and Virulence-Encoding Conjugative Plasmids in Klebsiella pneumoniae

(2020) Xuemei Yang et al.   TRENDS IN MICROBIOLOGY

Exploring the Potential of CRISPR-Cas9 Under Challenging Conditions: Facing High-Copy Plasmids and Counteracting Beta-Lactam Resistance in Clinical Strains of Enterobacteriaceae

(2020) Thaysa Leite Tagliaferri et al.   Frontiers in Microbiology

CRISPR/Cas9-mediated carbapenemase genes and plasmids curing in carbapenem-resistant Enterobacteriaceae

(2020) Mingju Hao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Harnessing the type I CRISPR‐Cas systems for genome editing in prokaryotes

(2020) Zeling Xu et al.   ENVIRONMENTAL MICROBIOLOGY

A compact Cascade–Cas3 system for targeted genome engineering

(2020) Bálint Csörgő et al.   NATURE METHODS

Convergence of virulence and MDR in a single plasmid vector in MDR Klebsiella pneumoniae ST15

(2019) Margaret M C Lam et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pandemic spread of blaKPC-2 among Klebsiella pneumoniae ST11 in China is associated with horizontal transfer mediated by IncFII-like plasmids

(2019) Pan Fu et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Eliminating mcr-1-harbouring plasmids in clinical isolates using the CRISPR/Cas9 system

(2019) Pengxia Wang et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus

(2019) Claudio Hidalgo-Cantabrana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using the Endogenous CRISPR-Cas System of Heliobacterium modesticaldum To Delete the Photochemical Reaction Center Core Subunit Gene

(2019) Patricia L. Baker et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Characterization and repurposing of the endogenous Type I-F CRISPR–Cas system of Zymomonas mobilis for genome engineering

(2019) Yanli Zheng et al.   NUCLEIC ACIDS RESEARCH

Efficient inter-species conjugative transfer of a CRISPR nuclease for targeted bacterial killing

(2019) Thomas A. Hamilton et al.   Nature Communications

Native CRISPR-Cas-Mediated Genome Editing Enables Dissecting and Sensitizing Clinical Multidrug-Resistant P. aeruginosa

(2019) Zeling Xu et al.   Cell Reports

Absence of the type I-E CRISPR-Cas system in Klebsiella pneumoniae clonal complex 258 is associated with dissemination of IncF epidemic resistance plasmids in this clonal complex

(2019) Yu Tang et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In silico typing and comparative genomic analysis of IncFIIK plasmids: insights into the evolution of replicons, plasmid backbones and resistance determinant profiles

(2018) Dexi Bi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of an XDR and carbapenemase-producing hypervirulent Klebsiella pneumoniae strain in Taiwan

(2018) Yen-Hua Huang et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Exploiting endogenous CRISPR-Cas system for multiplex genome editing in Clostridium tyrobutyricum and engineer the strain for high-level butanol production

(2018) Jie Zhang et al.   METABOLIC ENGINEERING

oriTfinder: a web-based tool for the identification of origin of transfers in DNA sequences of bacterial mobile genetic elements

(2018) Xiaobin Li et al.   NUCLEIC ACIDS RESEARCH

Rapid and precise alignment of raw reads against redundant databases with KMA

(2018) Philip T. L. C. Clausen et al.   BMC BIOINFORMATICS

CRISPR/Cas9-Mediated Re-Sensitization of Antibiotic-Resistant Escherichia coli Harboring Extended-Spectrum ��-Lactamases

(2016) Jun-Seob Kim et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Harnessing heterologous and endogenous CRISPR-Cas machineries for efficient markerless genome editing in Clostridium

(2016) Michael E. Pyne et al.   Scientific Reports

Mapping the resistance-associated mobilome of a carbapenem-resistantKlebsiella pneumoniaestrain reveals insights into factors shaping these regions and facilitates generation of a ‘resistance-disarmed’ model organism

(2015) Dexi Bi et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Persistence of a pKPN3-Like CTX-M-15-Encoding IncFIIK Plasmid in a Klebsiella pneumonia ST17 Host during Two Years of Intestinal Colonization

(2015) Iren Høyland Löhr et al.   PLoS One

Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding

(2014) Liang Chen et al.   TRENDS IN MICROBIOLOGY

Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems

(2014) A. A. Gomaa et al.   mBio

Dissemination of IncFIIK-type plasmids in multiresistant CTX-M-15-producing Enterobacteriaceae isolates from children in hospital paediatric oncology wards

(2012) Monika Dolejska et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

An optimized method for suicide vector-based allelic exchange in Klebsiella pneumoniae

(2011) Jon Jurriaan van Aartsen et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Complete Nucleotide Sequence of Klebsiella pneumoniae Multidrug Resistance Plasmid pKP048, Carrying blaKPC-2, blaDHA-1, qnrB4, and armA

(2010) Y. Jiang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Complete Nucleotide Sequence of KPC-3-Encoding Plasmid pKpQIL in the Epidemic Klebsiella pneumoniae Sequence Type 258

(2010) A. Leavitt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Replicon sequence typing of IncF plasmids carrying virulence and resistance determinants

(2010) Laura Villa et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Resistance Plasmid Families in Enterobacteriaceae

(2009) A. Carattoli   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Epidemic of Antibiotic-Resistant Infections: A Call to Action for the Medical Community from the Infectious Diseases Society of America

(2007) B. Spellberg et al.   CLINICAL INFECTIOUS DISEASES