Metabolism-dependent ferroptosis promotes mitochondrial dysfunction and inflammation in CD4+ T lymphocytes in HIV-infected immune non-responders

Scavenger receptor CD36 governs recruitment of myeloid cells to the blood–CSF barrier after stroke in neonatal mice

(2022) Aditya Rayasam et al.   Journal of Neuroinflammation

Bromodomains in Human-Immunodeficiency Virus-Associated Neurocognitive Disorders: A Model of Ferroptosis-Induced Neurodegeneration

(2022) Adonis Sfera et al.   Frontiers in Neuroscience

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability

(2021) Xingzhe Ma et al.   Cell Metabolism

NLRP3 inflammasome induces CD4+ T cell loss in chronically HIV-1–infected patients

(2021) Chao Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

The accumulation of plasma acylcarnitines are associated with poor immune recovery in HIV-infected individuals

(2021) Shi Qian et al.   BMC INFECTIOUS DISEASES

Dynamics of HIV reservoir decay and naïve CD4 T-cell recovery between immune non-responders and complete responders on long-term antiretroviral treatment

(2021) Lu-Xue Zhang et al.   CLINICAL IMMUNOLOGY

Mitochondrial regulation of ferroptosis

(2021) Boyi Gan   JOURNAL OF CELL BIOLOGY

“Go”, “No Go,” or “Where to Go”; does microbiota dictate T cell exhaustion, programming, and HIV persistence?

(2021) Sudhanshu Shukla et al.   Current Opinion in HIV and AIDS

Incomplete immune reconstitution in HIV/AIDS patients on antiretroviral therapy: Challenges of immunological non‐responders

(2020) Xiaodong Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Expanding TREC and KREC Utility in Primary Immunodeficiency Diseases Diagnosis

(2020) Ilya Korsunskiy et al.   Frontiers in Immunology

Transferrin Receptor Is a Specific Ferroptosis Marker

(2020) Huizhong Feng et al.   Cell Reports

Dexmedetomidine Ameliorates Lung Injury Induced by Intestinal Ischemia/Reperfusion by Upregulating Cannabinoid Receptor 2, Followed by the Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway

(2020) Meng Chen et al.   Oxidative Medicine and Cellular Longevity

Emerging Mechanisms and Disease Relevance of Ferroptosis

(2020) Brent R. Stockwell et al.   TRENDS IN CELL BIOLOGY

Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells

(2020) Hao Li et al.   Nature Communications

Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis

(2020) Nandini Verma et al.   Science Advances

The effect of type 2 diabetes on CD36 expression and the uptake of oxLDL

(2020) Atsushi Kanoke et al.   EXPERIMENTAL NEUROLOGY

Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism

(2020) Cristina Fernández-Mendívil et al.   Redox Biology

Changes in Lipid Indices in HIV+ Cases on HAART

(2019) Shujing Ji et al.   Biomed Research International

Cryo-EM structure of the human ferritin–transferrin receptor 1 complex

(2019) Linda Celeste Montemiglio et al.   Nature Communications

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

(2019) Weimin Wang et al.   NATURE

Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease

(2019) Antigoni Morou et al.   NATURE IMMUNOLOGY

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

(2019) Masahiro Yoshida et al.   Nature Communications

Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases

(2019) Toshitaka Nakamura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11

(2019) Xueting Lang et al.   Cancer Discovery

Advanced HIV: diagnosis, treatment, and prevention

(2019) Sandeep Prabhu et al.   Lancet HIV

Programmed Cell-Death by Ferroptosis: Antioxidants as Mitigators

(2019) Kajarabille et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immunological recovery failure in cART‐treated HIV‐positive patients is associated with reduced thymic output and RTE CD4+ T cell death by pyroptosis

(2019) Wlisses Henrique Veloso Carvalho‐Silva et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cell generation dynamics underlying naive T-cell homeostasis in adult humans

(2019) Jeff E. Mold et al.   PLOS BIOLOGY

Insight into the mechanism of ferroptosis inhibition by ferrostatin-1

(2019) Giovanni Miotto et al.   Redox Biology

Reinterpreting recent thymic emigrant function: defective or adaptive?

(2018) Cody A Cunningham et al.   CURRENT OPINION IN IMMUNOLOGY

Inhibition of microRNA-210 suppresses pro-inflammatory response and reduces acute brain injury of ischemic stroke in mice

(2018) Lei Huang et al.   EXPERIMENTAL NEUROLOGY

CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis

(2018) Lei Zhao et al.   JOURNAL OF HEPATOLOGY

Pre-treatment of soybean plants with calcium stimulates ROS responses and mitigates infection by Sclerotinia sclerotiorum

(2018) Arbia Arfaoui et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

(2018) Róisín M. Loftus et al.   Nature Communications

Modeling the effects of lipid peroxidation during ferroptosis on membrane properties

(2018) Eran Agmon et al.   Scientific Reports

Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

(2018) Huizhong Feng et al.   PLOS BIOLOGY

Assessment of a Noninvasive Exhaled Breath Test for the Diagnosis of Oesophagogastric Cancer

(2018) Sheraz R. Markar et al.   JAMA Oncology

Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults

(2018) Michael S. Saag et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Distinct Mitochondrial Disturbance in CD4+T and CD8+T Cells From HIV-Infected Patients

(2017) Fengting Yu et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Mitochondrial function in hypoxic ischemic injury and influence of aging

(2017) P. Benson Ham et al.   PROGRESS IN NEUROBIOLOGY

Mechanical Communication at the Immunological Synapse

(2017) Roshni Basu et al.   TRENDS IN CELL BIOLOGY

SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages

(2017) Lin Luo et al.   Nature Communications

CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function

(2017) Arata Takeuchi et al.   Frontiers in Immunology

Immunologic profiles distinguish aviremic HIV-infected adults

(2016) Christina M. Ramirez et al.   AIDS

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

(2016) Michael D. Buck et al.   CELL

Toward high-content screening of mitochondrial morphology and membrane potential in living cells

(2015) Eligio F. Iannetti et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Adipose and Muscle Tissue Profile of CD36 Transcripts in Obese Subjects Highlights the Role of CD36 in Fatty Acid Homeostasis and Insulin Resistance

(2014) Terri A. Pietka et al.   DIABETES CARE

Nanoparticles With Surface Antibody Against CD98 and Carrying CD98 Small Interfering RNA Reduce Colitis in Mice

(2014) Bo Xiao et al.   GASTROENTEROLOGY

HIV-associated chronic immune activation

(2013) Mirko Paiardini et al.   IMMUNOLOGICAL REVIEWS

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Oxidative Stress and Mitochondrial Impairment After Treatment with Anti-HIV Drugs: Clinical Implications

(2012) Ana Blas-Garcia et al.   CURRENT PHARMACEUTICAL DESIGN

Prognostic value of the immunological phenomena and relationship with clinicopathological characteristics of the tumor — the expression of the early CD69+, CD71+and the late CD25+, CD26+, HLA/DR + activation markers on T CD4+ and CD8+ lymphocytes in squamous cell laryngeal carcinoma. Part II

(2012) Katarzyna Starska et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

HIV-1 Infection and First Line ART Induced Differential Responses in Mitochondria from Blood Lymphocytes and Monocytes: The ANRS EP45 “Aging” Study

(2012) Sophie Perrin et al.   PLoS One

Cord blood monocyte subsets are similar to adult and show potent peptidoglycan-stimulated cytokine responses

(2011) Ebba Sohlberg et al.   IMMUNOLOGY

Glutamate release by primary brain tumors induces epileptic activity

(2011) Susan C Buckingham et al.   NATURE MEDICINE

Biological Determinants of Immune Reconstitution in HIV‐Infected Patients Receiving Antiretroviral Therapy: The Role of Interleukin 7 and Interleukin 7 Receptor α and Microbial Translocation

(2010) Reena Rajasuriar et al.   JOURNAL OF INFECTIOUS DISEASES

Novel mechanism of U18666A-induced tumour necrosis factor-α production in RAW 264·7 macrophage cells

(2009) I. Iftakhar-E-Khuda et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

(2009) R. L. Silverstein et al.   Science Signaling