RNA G-quadruplex forming regions from SARS-2, SARS-1 and MERS coronoviruses

RNA G-quadruplex in TMPRSS2 reduces SARS-CoV-2 infection

(2022) Geng Liu et al.   Nature Communications

RNA G-quadruplex formed in SARS-CoV-2 used for COVID-19 treatment in animal models

(2022) Geng Qin et al.   Cell Discovery

Chemical shift prediction of RNA imino groups: application toward characterizing RNA excited states

(2021) Yanjiao Wang et al.   Nature Communications

Evolution of Diverse Strategies for Promoter Regulation

(2021) Václav Brázda et al.   TRENDS IN GENETICS

Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis

(2021) Florian Kabinger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction

(2021) Marc Lavigne et al.   NUCLEIC ACIDS RESEARCH

Unlocking G-Quadruplexes as Antiviral Targets

(2021) Ardavan Abiri et al.   PHARMACOLOGICAL REVIEWS

Potential G-quadruplexes and i-Motifs in the SARS-CoV-2

(2021) Efres Belmonte-Reche et al.   PLoS One

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

(2021) Sara Lago et al.   Nature Communications

An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19

(2021) Dafydd R. Owen et al.   SCIENCE

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia

(2020) Qun Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

(2020) Emmie de Wit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

(2020) Carly G.K. Ziegler et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial

(2020) Feng-Cai Zhu et al.   LANCET

G-Quadruplexes at Telomeres: Friend or Foe?

(2020) Tracy M. Bryan   MOLECULES

In-Depth Bioinformatic Analyses of Nidovirales Including Human SARS-CoV-2, SARS-CoV, MERS-CoV Viruses Suggest Important Roles of Non-canonical Nucleic Acid Structures in Their Lifecycles

(2020) Martin Bartas et al.   Frontiers in Microbiology

Targeting RNA G‐quadruplex in SARS‐CoV‐2: A Promising Therapeutic Target for COVID‐19?

(2020) Xiaogang Qu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Is There a Link Between the Pathogenic Human Coronavirus Envelope Protein and Immunopathology? A Review of the Literature

(2020) Dewald Schoeman et al.   Frontiers in Microbiology

SARS-CoV-2 hot-spot mutations are significantly enriched within inverted repeats and CpG island loci

(2020) Pratik Goswami et al.   BRIEFINGS IN BIOINFORMATICS

Conserved Secondary Structures in Viral mRNAs

(2019) Kiening et al.   Viruses-Basel

Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein

(2018) Jian Lei et al.   ANTIVIRAL RESEARCH

Coronavirus S protein-induced fusion is blocked prior to hemifusion by Abl kinase inhibitors

(2018) Jeanne M. Sisk et al.   JOURNAL OF GENERAL VIROLOGY

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy

(2018) Emanuela Ruggiero et al.   NUCLEIC ACIDS RESEARCH

RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand

(2018) Jaubert Chloé et al.   Scientific Reports

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication

(2018) Wen-Xiu Bian et al.   NUCLEIC ACIDS RESEARCH

A G-quadruplex motif in an envelope gene promoter regulates transcription and virion secretion in HBV genotype B

(2017) Banhi Biswas et al.   NUCLEIC ACIDS RESEARCH

Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA

(2017) María José Lista et al.   Nature Communications

A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication

(2017) Sara Callegaro et al.   Scientific Reports

RNA G-quadruplexes: emerging mechanisms in disease

(2016) Anne Cammas et al.   NUCLEIC ACIDS RESEARCH

Re-evaluation of G-quadruplex propensity with G4Hunter

(2016) Amina Bedrat et al.   NUCLEIC ACIDS RESEARCH

Mechanical insights into ribosomal progression overcoming RNA G-quadruplex from periodical translation suppression in cells

(2016) Tamaki Endoh et al.   Scientific Reports

A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti-hepatitis C target

(2016) S.-R. Wang et al.   Science Advances

Accessory proteins of SARS-CoV and other coronaviruses

(2014) Ding Xiang Liu et al.   ANTIVIRAL RESEARCH

Topology of a DNA G-Quadruplex Structure Formed in the HIV-1 Promoter: A Potential Target for Anti-HIV Drug Development

(2014) Samir Amrane et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

G-quadruplexes regulate Epstein-Barr virus–encoded nuclear antigen 1 mRNA translation

(2014) Pierre Murat et al.   Nature Chemical Biology

Mapping overlapping functional elements embedded within the protein-coding regions of RNA viruses

(2014) Andrew E. Firth   NUCLEIC ACIDS RESEARCH

G-quadruplexes in viruses: function and potential therapeutic applications

(2014) Mathieu Métifiot et al.   NUCLEIC ACIDS RESEARCH

DNA G-quadruplex and its potential as anticancer drug target

(2014) Buket Onel et al.   Science China-Chemistry

Suppression of Gene Expression by G-Quadruplexes in Open Reading Frames Depends on G-Quadruplex Stability

(2013) Tamaki Endoh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group

(2013) R. J. de Groot et al.   JOURNAL OF VIROLOGY

In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features

(2013) Yiliang Ding et al.   NATURE

Stimulation of ribosomal frameshifting by RNA G-quadruplex structures

(2013) Chien-Hung Yu et al.   NUCLEIC ACIDS RESEARCH

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

RNA dimerization plays a role in ribosomal frameshifting of the SARS coronavirus

(2012) Daniella Ishimaru et al.   NUCLEIC ACIDS RESEARCH

G4LDB: a database for discovering and studying G-quadruplex ligands

(2012) Qian Li et al.   NUCLEIC ACIDS RESEARCH

HIV-1 Nucleocapsid Protein Increases Strand Transfer Recombination by Promoting Dimeric G-quartet Formation

(2011) Wen Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY