Extracellular vesicles produced by the human gut commensal bacterium Bacteroides thetaiotaomicron elicit anti-inflammatory responses from innate immune cells

Endotoxin tolerance induced by Porphyromonas gingivalis lipopolysaccharide alters macrophage polarization

(2022) Jian-Yu Gu et al.   MICROBIAL PATHOGENESIS

Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell‐type specific manner that are altered in inflammatory bowel disease

(2022) Lejla Gul et al.   Journal of Extracellular Vesicles

Lipidomics Analysis of Outer Membrane Vesicles and Elucidation of the Inositol Phosphoceramide Biosynthetic Pathway in Bacteroides thetaiotaomicron

(2022) Mariana G. Sartorio et al.   Microbiology Spectrum

One genome, many cell states: epigenetic control of innate immunity

(2022) Isabella Fraschilla et al.   CURRENT OPINION IN IMMUNOLOGY

Outer Membrane Vesicles: Biogenesis, Functions, and Issues

(2022) Rokas Juodeikis et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Uptake, Trafficking, and Biodistribution of Bacteroides thetaiotaomicron Generated Outer Membrane Vesicles

(2020) Emily J. Jones et al.   Frontiers in Microbiology

Understanding the Relevance of DNA Methylation Changes in Immune Differentiation and Disease

(2020) Carlos de la Calle-Fabregat et al.   Genes

Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

(2020) Lydia Durant et al.   Microbiome

Bacteroides thetaiotaomicron relieves colon inflammation by activating aryl hydrocarbon receptor and modulating CD4+T cell homeostasis

(2020) Keying Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Use of bioengineered human commensal gut bacteria‐derived microvesicles for mucosal plague vaccine delivery and immunization

(2019) A. L. Carvalho et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Weak agonistic LPS restores intestinal immune homeostasis

(2019) Alex Steimle et al.   MOLECULAR THERAPY

Bioengineering commensal bacteria-derived outer membrane vesicles for delivery of biologics to the gastrointestinal and respiratory tract

(2019) Ana L. Carvalho et al.   Journal of Extracellular Vesicles

Membrane vesicles from the probiotic Nissle 1917 and gut resident Escherichia coli strains distinctly modulate human dendritic cells and subsequent T cell responses

(2019) Natalia Diaz-Garrido et al.   Journal of Functional Foods

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

(2018) Ioannis Mitroulis et al.   CELL

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis

(2018) Eva Kaufmann et al.   CELL

Toll-Like Receptor 2-Mediated Suppression of Colorectal Cancer Pathogenesis by Polysaccharide A From Bacteroides fragilis

(2018) Panida Sittipo et al.   Frontiers in Microbiology

Fantastic voyage: the journey of intestinal microbiota-derived microvesicles through the body

(2018) Régis Stentz et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Bacteroides thetaiotaomicron Ameliorates Colon Inflammation in Preclinical Models of Crohn’s Disease

(2018) Margaret Delday et al.   INFLAMMATORY BOWEL DISEASES

Deposition and hydrolysis of serine dipeptide lipids of Bacteroidetes bacteria in human arteries: relationship to atherosclerosis

(2017) Reza Nemati et al.   JOURNAL OF LIPID RESEARCH

TLR2 and interleukin-10 are involved in Bacteroides fragilis-mediated prevention of DSS-induced colitis in gnotobiotic mice

(2017) Yi-Chih Chang et al.   PLoS One

In Silico Analysis of the Small Molecule Content of Outer Membrane Vesicles Produced by Bacteroides thetaiotaomicron Indicates an Extensive Metabolic Link between Microbe and Host

(2017) William A. Bryant et al.   Frontiers in Microbiology

β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance

(2016) Boris Novakovic et al.   CELL

Molecular mechanisms of innate memory and tolerance to LPS

(2016) John J. Seeley et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

Lower Level of Bacteroides in the Gut Microbiota Is Associated with Inflammatory Bowel Disease: A Meta-Analysis

(2016) Yingting Zhou et al.   Biomed Research International

Trained immunity: A smart way to enhance innate immune defence

(2015) Jos W.M. van der Meer et al.   MOLECULAR IMMUNOLOGY

Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

(2015) Carmen Schwechheimer et al.   NATURE REVIEWS MICROBIOLOGY

Oxidized Low-Density Lipoprotein Induces Long-Term Proinflammatory Cytokine Production and Foam Cell Formation via Epigenetic Reprogramming of Monocytes

(2014) Siroon Bekkering et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors

(2014) Daniela C. Ifrim et al.   Clinical and Vaccine Immunology

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Dysregulation of mucosal immune response in pathogenesis of inflammatory bowel disease

(2014) Xiao-Rong Xu   WORLD JOURNAL OF GASTROENTEROLOGY

Monocolonization of Germ-Free Mice withBacteroides fragilisProtects against Dextran Sulfate Sodium-Induced Acute Colitis

(2014) Chien-Chao Chiu et al.   Biomed Research International

Toll-Like Receptor 2 Regulates Intestinal Inflammation by Controlling Integrity of the Enteric Nervous System

(2013) Paola Brun et al.   GASTROENTEROLOGY

Serine Lipids of Porphyromonas gingivalis Are Human and Mouse Toll-Like Receptor 2 Ligands

(2013) Robert B. Clark et al.   INFECTION AND IMMUNITY

Cutting Edge: An Inactive Chromatin Configuration at the IL-10 Locus in Human Neutrophils

(2013) N. Tamassia et al.   JOURNAL OF IMMUNOLOGY

TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors

(2013) Jeroen van Bergenhenegouwen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Outer Membrane Vesicles of a Human Commensal Mediate Immune Regulation and Disease Protection

(2012) Yue Shen et al.   Cell Host & Microbe

The pro- and anti-inflammatory properties of the cytokine interleukin-6

(2011) Jürgen Scheller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Application of ChIP-Seq and Related Techniques to the Study of Immune Function

(2011) Daniel L. Northrup et al.   IMMUNITY

Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa

(2011) Peter A. Bron et al.   NATURE REVIEWS MICROBIOLOGY

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

(2011) J. L. Round et al.   SCIENCE

Toll-Like Receptor 2 Signaling Protects Mice from Tumor Development in a Mouse Model of Colitis-Induced Cancer

(2010) Emily L. Lowe et al.   PLoS One

Gene expression patterns in experimental colitis in IL-10-deficient mice

(2009) Jonathan J. Hansen et al.   INFLAMMATORY BOWEL DISEASES

Endotoxin tolerance: new mechanisms, molecules and clinical significance

(2009) Subhra K. Biswas et al.   TRENDS IN IMMUNOLOGY

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE