Three-dimensional flagella structures from animals’ closest unicellular relatives, the Choanoflagellates

Cryo-EM structure of an active central apparatus

(2022) Long Han et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of a microtubule-bound axonemal dynein

(2021) Travis Walton et al.   Nature Communications

The multi‐scale architecture of mammalian sperm flagella and implications for ciliary motility

(2021) Miguel Ricardo Leung et al.   EMBO JOURNAL

Structural insights into the cause of human RSPH4A primary ciliary dyskinesia

(2021) Yanhe Zhao et al.   MOLECULAR BIOLOGY OF THE CELL

Detection of horizontal gene transfer in the genome of the choanoflagellate Salpingoeca rosetta

(2021) Danielle M. Matriano et al.   Scientific Reports

Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism

(2021) Qinhui Rao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins

(2021) Xiangli Wang et al.   Nature Communications

Electron cryo-tomography structure of axonemal doublet microtubule from Tetrahymena thermophila

(2021) Sam Li et al.   Life Science Alliance

The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications

(2020) Ahmad Abdelzaher Zaki Khalifa et al.   eLife

Chlamydomonas PKD2 organizes mastigonemes, hair-like glycoprotein polymers on cilia

(2020) Peiwei Liu et al.   JOURNAL OF CELL BIOLOGY

The structure and symmetry of radial spoke protein complex in Chlamydomonas flagella

(2020) E. Poghosyan et al.   JOURNAL OF CELL SCIENCE

Genome editing enables reverse genetics of multicellular development in the choanoflagellate Salpingoeca rosetta

(2020) David S Booth et al.   eLife

Structures of radial spokes and associated complexes important for ciliary motility

(2020) Miao Gui et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating

(2020) Iris Grossman-Haham et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inner lumen proteins stabilize doublet microtubules in cilia and flagella

(2019) Mikito Owa et al.   Nature Communications

PACRG and FAP20 form the inner junction of axonemal doublet microtubules and regulate ciliary motility

(2019) Erin E. Dymek et al.   MOLECULAR BIOLOGY OF THE CELL

Structure of the Decorated Ciliary Doublet Microtubule

(2019) Meisheng Ma et al.   CELL

Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus

(2019) Gang Fu et al.   JOURNAL OF CELL BIOLOGY

In situ structure determination at nanometer resolution using TYGRESS

(2019) Kangkang Song et al.   NATURE METHODS

Cryo electron tomography with Volta phase plate reveals novel structural foundations of the 96-nm axonemal repeat in the pathogen Trypanosoma brucei

(2019) Simon Imhof et al.   eLife

Flagellar-associated Protein FAP85 Is a Microtubule Inner Protein That Stabilizes Microtubules

(2018) Junya Kirima et al.   CELL STRUCTURE AND FUNCTION

The I1 dynein-associated tether and tether head complex is a conserved regulator of ciliary motility

(2018) Gang Fu et al.   MOLECULAR BIOLOGY OF THE CELL

Asymmetric distribution and spatial switching of dynein activity generates ciliary motility

(2018) Jianfeng Lin et al.   SCIENCE

Systematic studies of all PIH proteins in zebrafish reveal their distinct roles in axonemal dynein assembly

(2018) Hiroshi Yamaguchi et al.   eLife

Transfection of choanoflagellates illuminates their cell biology and the ancestry of animal septins

(2018) David S. Booth et al.   MOLECULAR BIOLOGY OF THE CELL

Predicted glycosyltransferases promote development and prevent spurious cell clumping in the choanoflagellate S. rosetta

(2018) Laura A Wetzel et al.   eLife

Uncharacterized Bacterial Structures Revealed by Electron Cryotomography

(2017) Megan J. Dobro et al.   JOURNAL OF BACTERIOLOGY

Optimized cryo-focused ion beam sample preparation aimed at in situ structural studies of membrane proteins

(2017) Miroslava Schaffer et al.   JOURNAL OF STRUCTURAL BIOLOGY

Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging

(2017) Wim J.H. Hagen et al.   JOURNAL OF STRUCTURAL BIOLOGY

Genes and molecular pathways underpinning ciliopathies

(2017) Jeremy F. Reiter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hydrodynamics of microbial filter feeding

(2017) Lasse Tor Nielsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subnanometre-resolution structure of the doublet microtubule reveals new classes of microtubule-associated proteins

(2017) Muneyoshi Ichikawa et al.   Nature Communications

Fine-Tuning Motile Cilia and Flagella: Evolution of the Dynein Motor Proteins from Plants to Humans at High Resolution

(2016) Martin Kollmar   MOLECULAR BIOLOGY AND EVOLUTION

Comparative Ultrastructure of Fornicate Excavates, Including a Novel Free-living Relative of Diplomonads: Aduncisulcus paluster gen. et sp. nov.

(2016) Naoji Yubuki et al.   PROTIST

Radial Spokes—A Snapshot of the Motility Regulation, Assembly, and Evolution of Cilia and Flagella

(2016) Xiaoyan Zhu et al.   Cold Spring Harbor Perspectives in Biology

α- and β-Tubulin Lattice of the Axonemal Microtubule Doublet and Binding Proteins Revealed by Single Particle Cryo-Electron Microscopy and Tomography

(2015) Aditi Maheshwari et al.   STRUCTURE

Choanoflagellate and choanocyte collar-flagellar systems and the assumption of homology

(2014) Jasmine L. Mah et al.   EVOLUTION & DEVELOPMENT

Prey Capture and Phagocytosis in the Choanoflagellate Salpingoeca rosetta

(2014) Mark J. Dayel et al.   PLoS One

Volta potential phase plate for in-focus phase contrast transmission electron microscopy

(2014) R. Danev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Eukaryotic Tree of Life from a Global Phylogenomic Perspective

(2014) F. Burki   Cold Spring Harbor Perspectives in Biology

Cryo-electron tomography reveals ciliary defects underlying human RSPH1 primary ciliary dyskinesia

(2014) Jianfeng Lin et al.   Nature Communications

Evidence for Sex and Recombination in the Choanoflagellate Salpingoeca rosetta

(2013) Tera C. Levin et al.   CURRENT BIOLOGY

Conserved structural motifs in the central pair complex of eukaryotic flagella

(2012) Blanca I. Carbajal-González et al.   Cytoskeleton

Comparative structural analysis of eukaryotic flagella and cilia from Chlamydomonas, Tetrahymena, and sea urchins

(2012) Gaia Pigino et al.   JOURNAL OF STRUCTURAL BIOLOGY

A Detailed, Hierarchical Study of Giardia lamblia's Ventral Disc Reveals Novel Microtubule-Associated Protein Complexes

(2012) Cindi L. Schwartz et al.   PLoS One

One of the Nine Doublet Microtubules of Eukaryotic Flagella Exhibits Unique and Partially Conserved Structures

(2012) Jianfeng Lin et al.   PLoS One

The structural heterogeneity of radial spokes in cilia and flagella is conserved

(2011) Jianfeng Lin et al.   Cytoskeleton

Cell differentiation and morphogenesis in the colony-forming choanoflagellate Salpingoeca rosetta

(2011) Mark J. Dayel et al.   DEVELOPMENTAL BIOLOGY

Structure and function of vertebrate cilia, towards a new taxonomy

(2011) Sen Takeda et al.   DIFFERENTIATION

Cryoelectron tomography of radial spokes in cilia and flagella

(2011) Gaia Pigino et al.   JOURNAL OF CELL BIOLOGY

Clustering and variance maps for cryo-electron tomography using wedge-masked differences

(2011) John M. Heumann et al.   JOURNAL OF STRUCTURAL BIOLOGY

Three-dimensional structure of the radial spokes reveals heterogeneity and interactions with dyneins in Chlamydomonas flagella

(2011) Cynthia F. Barber et al.   MOLECULAR BIOLOGY OF THE CELL

Cryo-electron tomography reveals conserved features of doublet microtubules in flagella

(2011) D. Nicastro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensory reception is an attribute of both primary cilia and motile cilia

(2010) R. A. Bloodgood   JOURNAL OF CELL SCIENCE

The presence of flagellar vanes in choanomeres of Porifera and their possible phylogenetic implications

(2010) Dorte Mehl et al.   JOURNAL OF ZOOLOGICAL SYSTEMATICS AND EVOLUTIONARY RESEARCH

The paraflagellar rod of kinetoplastid parasites: From structure to components and function

(2009) Neil Portman et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A Phylogenomic Investigation into the Origin of Metazoa

(2008) Iñaki Ruiz-Trillo et al.   MOLECULAR BIOLOGY AND EVOLUTION

Molecular phylogeny of choanoflagellates, the sister group to Metazoa

(2008) M. Carr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA