Structures of radial spokes and associated complexes important for ciliary motility

The structure and symmetry of radial spoke protein complex in Chlamydomonas flagella

(2020) E. Poghosyan et al.   JOURNAL OF CELL SCIENCE

Redox regulation of motile cilia in airway disease

(2019) Michael E. Price et al.   Redox Biology

Software tools for automated transmission electron microscopy

(2019) Martin Schorb et al.   NATURE METHODS

Structure of the Decorated Ciliary Doublet Microtubule

(2019) Meisheng Ma et al.   CELL

A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1)

(2018) Tomohiro Kubo et al.   MOLECULAR BIOLOGY OF THE CELL

Asymmetric distribution and spatial switching of dynein activity generates ciliary motility

(2018) Jianfeng Lin et al.   SCIENCE

Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION

(2018) Takanori Nakane et al.   eLife

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

In vivo analyses of radial spoke transport, assembly, repair and maintenance

(2018) Karl F. Lechtreck et al.   Cytoskeleton

The roles of a flagellar HSP40 ensuring rhythmic beating

(2018) Xiaoyan Zhu et al.   MOLECULAR BIOLOGY OF THE CELL

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Genes and molecular pathways underpinning ciliopathies

(2017) Jeremy F. Reiter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Mutations in DNAJB13 , Encoding an HSP40 Family Member, Cause Primary Ciliary Dyskinesia and Male Infertility

(2016) Elma El Khouri et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Calmodulin in complex with the first IQ motif of myosin-5a functions as an intact calcium sensor

(2016) Mei Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cilia-based flow network in the brain ventricles

(2016) R. Faubel et al.   SCIENCE

Axoneme Structure from Motile Cilia

(2016) Takashi Ishikawa   Cold Spring Harbor Perspectives in Biology

Cilia and Mucociliary Clearance

(2016) Ximena M. Bustamante-Marin et al.   Cold Spring Harbor Perspectives in Biology

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

The CSC proteins FAP61 and FAP251 build the basal substructures of radial spoke 3 in cilia

(2015) Paulina Urbanska et al.   MOLECULAR BIOLOGY OF THE CELL

A NIMA-Related Kinase Suppresses the Flagellar Instability Associated with the Loss of Multiple Axonemal Structures

(2015) Huawen Lin et al.   PLoS Genetics

High-resolution crystal structures of the solubilized domain of porcine cytochromeb5

(2015) Yu Hirano et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mechanosignaling between central apparatus and radial spokes controls axonemal dynein activity

(2014) Toshiyuki Oda et al.   JOURNAL OF CELL BIOLOGY

A molecular ruler determines the repeat length in eukaryotic cilia and flagella

(2014) T. Oda et al.   SCIENCE

Cryo-electron tomography reveals ciliary defects underlying human RSPH1 primary ciliary dyskinesia

(2014) Jianfeng Lin et al.   Nature Communications

Identification of the Outer-Inner Dynein Linker as a Hub Controller for Axonemal Dynein Activities

(2013) Toshiyuki Oda et al.   CURRENT BIOLOGY

The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes

(2013) Raqual Bower et al.   MOLECULAR BIOLOGY OF THE CELL

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

The versatile molecular complex component LC8 promotes several distinct steps of flagellar assembly

(2012) Anjali Gupta et al.   JOURNAL OF CELL BIOLOGY

Sequential assembly of flagellar radial spokes

(2011) Dennis R. Diener et al.   Cytoskeleton

Building Blocks of the Nexin-Dynein Regulatory Complex inChlamydomonasFlagella

(2011) Jianfeng Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryoelectron tomography of radial spokes in cilia and flagella

(2011) Gaia Pigino et al.   JOURNAL OF CELL BIOLOGY

The CSC is required for complete radial spoke assembly and wild-type ciliary motility

(2011) Erin E. Dymek et al.   MOLECULAR BIOLOGY OF THE CELL

Three-dimensional structure of the radial spokes reveals heterogeneity and interactions with dyneins in Chlamydomonas flagella

(2011) Cynthia F. Barber et al.   MOLECULAR BIOLOGY OF THE CELL

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase

(2010) Judith Scoble et al.   JOURNAL OF MOLECULAR BIOLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Proteomic characterization of sperm radial spokes identifies a novel spoke protein with an ubiquitin domain

(2009) Yuhkoh Satouh et al.   FEBS LETTERS

The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella

(2009) Thomas Heuser et al.   JOURNAL OF CELL BIOLOGY

Swimming with protists: perception, motility and flagellum assembly

(2008) Michael L. Ginger et al.   NATURE REVIEWS MICROBIOLOGY