The biosynthesis and genetic engineering of bioactive indole alkaloids in plants
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Title
The biosynthesis and genetic engineering of bioactive indole alkaloids in plants
Authors
Keywords
Biosynthesis, Indole alkaloids, Metabolic engineering, Shikimate pathway, Transcription factor, Translocator, Vinblastine
Journal
JOURNAL OF PLANT BIOLOGY
Volume 59, Issue 3, Pages 203-214
Publisher
Springer Nature
Online
2016-06-03
DOI
10.1007/s12374-016-0032-5
References
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- Ergot alkaloids: structure diversity, biosynthetic gene clusters and functional proof of biosynthetic genes
- (2010) Christiane Wallwey et al. NATURAL PRODUCT REPORTS
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- (2010) Harry J. Klee NEW PHYTOLOGIST
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- (2010) Q. Zhang et al. PLANT CELL
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- Tubulin-Interactive Natural Products as Anticancer Agents(1)
- (2009) David G. I. Kingston JOURNAL OF NATURAL PRODUCTS
- Inducible expression of a Nep1-like protein serves as a model trigger system of camalexin biosynthesis
- (2009) Thomas Rauhut et al. PHYTOCHEMISTRY
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- Alkaloid Biosynthesis: Metabolism and Trafficking
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- Cytotoxicity of the β-carboline alkaloids harmine and harmaline in human cell assays in vitro
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- Overexpression of 1-Deoxy-d-xylulose-5-phosphate reductoisomerase gene in chloroplast contributes to increment of isoprenoid production
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- ArabidopsisIndole Synthase, a Homolog of Tryptophan Synthase Alpha, is an Enzyme Involved in the Trp-independent Indole-containing Metabolite Biosynthesis
- (2008) Rui Zhang et al. Journal of Integrative Plant Biology
- Transcriptional response of the terpenoid indole alkaloid pathway to the overexpression of ORCA3 along with jasmonic acid elicitation of Catharanthus roseus hairy roots over time
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- The Leaf Epidermome of Catharanthus roseus Reveals Its Biochemical Specialization
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- Alpha-tryptophan synthase of Isatis tinctoria: gene cloning and expression
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