A tick C1q protein alters infectivity of the Lyme disease agent by modulating interferon γ

Borrelia burgdorferi is a poor inducer of interferon-gamma: amplification induced by interleukin-12

(2022) F.R. van de Schoor et al.   INFECTION AND IMMUNITY

Changing the Recipe: Pathogen Directed Changes in Tick Saliva Components

(2021) Michael Pham et al.   International Journal of Environmental Research and Public Health

mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent

(2021) Andaleeb Sajid et al.   Science Translational Medicine

The Lyme disease agent co-opts adiponectin receptor-mediated signaling in its arthropod vector

(2021) Xiaotian Tang et al.   eLife

Mitochondrial C1qbp promotes differentiation of effector CD8 + T cells via metabolic-epigenetic reprogramming

(2021) Xingyuan Zhai et al.   Science Advances

Utilization of complement receptors in immune cell–microbe interaction

(2020) Szilvia Lukácsi et al.   FEBS LETTERS

Interactions between Borrelia burgdorferi and ticks

(2020) Cheyne Kurokawa et al.   NATURE REVIEWS MICROBIOLOGY

Adiponectin and related C1q/TNF-related proteins bind selectively to anionic phospholipids and sphingolipids

(2020) Jessica J. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Implications of the Adiponectin System in Non-Small Cell Lung Cancer Patients: A Case-Control Study

(2020) Ersilia Nigro et al.   Biomolecules

An Ixodes scapularis protein disulfide isomerase contributes to Borrelia burgdorferi colonization of the vector

(2020) Yongguo Cao et al.   INFECTION AND IMMUNITY

SLE: Novel Postulates for Therapeutic Options

(2020) Kinga K. Hosszu et al.   Frontiers in Immunology

Aedes aegypti AgBR1 antibodies modulate early Zika virus infection of mice

(2019) Ryuta Uraki et al.   Nature Microbiology

Structural determination of the complement inhibitory domain of Borrelia burgdorferi BBK32 provides insight into classical pathway complement evasion by lyme disease spirochetes

(2019) Jialei Xie et al.   PLoS Pathogens

A gene expression network analysis of the pancreatic islets from lean and obese mice identifies complement 1q like-3 secreted protein as a regulator of β-cell function

(2019) James E. Koltes et al.   Scientific Reports

Comparative study of three C1q domain containing proteins from pacific oyster Crassostrea gigas

(2018) Zhao Lv et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission

(2018) Thomas Hart et al.   PLoS Pathogens

Vital Signs: Trends in Reported Vectorborne Disease Cases — United States and Territories, 2004–2016

(2018) Ronald Rosenberg et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Recombinant CTRP9 administration attenuates neuroinflammation via activating adiponectin receptor 1 after intracerebral hemorrhage in mice

(2018) Lianhua Zhao et al.   Journal of Neuroinflammation

A novel globular C1q domain containing protein (C1qDC-7) from Crassostrea gigas acts as pattern recognition receptor with broad recognition spectrum

(2018) Yanan Zong et al.   FISH & SHELLFISH IMMUNOLOGY

Cross-Species Interferon Signaling Boosts Microbicidal Activity within the Tick Vector

(2016) Alexis A. Smith et al.   Cell Host & Microbe

Hijacking Complement Regulatory Proteins for Bacterial Immune Evasion

(2016) Elise S. Hovingh et al.   Frontiers in Microbiology

Analysis of the Interaction between Globular Head Modules of Human C1q and Its Candidate Receptor gC1qR

(2016) Lina Pednekar et al.   Frontiers in Immunology

Structures of C1q-like Proteins Reveal Unique Features among the C1q/TNF Superfamily

(2015) Susanne Ressl et al.   STRUCTURE

Pattern of Proinflammatory Cytokine Induction in RAW264.7 Mouse Macrophages Is Identical for Virulent and Attenuated Borrelia burgdorferi

(2014) G. Wang et al.   JOURNAL OF IMMUNOLOGY

Complement Is Activated by IgG Hexamers Assembled at the Cell Surface

(2014) C. A. Diebolder et al.   SCIENCE

Horizontal gene transfer of a vertebrate vasodilatory hormone into ticks

(2014) Shiroh Iwanaga et al.   Nature Communications

An Alternative Role of C1q in Bacterial Infections: Facilitating Streptococcus pneumoniae Adherence and Invasion of Host Cells

(2013) V. Agarwal et al.   JOURNAL OF IMMUNOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A C1q Domain Containing Protein from Scallop Chlamys farreri Serving as Pattern Recognition Receptor with Heat-Aggregated IgG Binding Activity

(2012) Leilei Wang et al.   PLoS One

A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent

(2011) Tim J. Schuijt et al.   Cell Host & Microbe

Metabolic Regulation by C1q/TNF-related Protein-13 (CTRP13)

(2011) Zhikui Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Characterization of Ixodes scapularis Antigens That Elicit Tick Immunity Using Yeast Surface Display

(2011) Tim J. Schuijt et al.   PLoS One

The complement system

(2010) J. Vidya Sarma et al.   CELL AND TISSUE RESEARCH

The C1q domain containing proteins: Where do they come from and what do they do?

(2010) Tristan M. Carland et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

C1q/TNF-Related Protein-3 Represents a Novel and Endogenous Lipopolysaccharide Antagonist of the Adipose Tissue

(2010) Andrea Kopp et al.   ENDOCRINOLOGY

Tick Histamine Release Factor Is Critical for Ixodes scapularis Engorgement and Transmission of the Lyme Disease Agent

(2010) Jianfeng Dai et al.   PLoS Pathogens

Borrelia burgdorferiStimulates Macrophages to Secrete Higher Levels of Cytokines and Chemokines thanBorrelia afzeliiorBorrelia garinii

(2009) Klemen Strle et al.   JOURNAL OF INFECTIOUS DISEASES

Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-γ agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions

(2008) G. William Wong et al.   BIOCHEMICAL JOURNAL

Secretion of interferon-γ by human macrophages demonstrated at the single-cell level after costimulation with interleukin (IL)-12 plus IL-18

(2008) Laila Darwich et al.   IMMUNOLOGY