mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent

Ixodes scapularis saliva components that elicit responses associated with acquired tick-resistance

(2020) Sukanya Narasimhan et al.   Ticks and Tick-Borne Diseases

Time-resolved proteomic profile of Amblyomma americanum tick saliva during feeding

(2020) Tae Kwon Kim et al.   PLoS Neglected Tropical Diseases

A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice

(2020) Alec W. Freyn et al.   MOLECULAR THERAPY

Recent advances in mRNA vaccine technology

(2020) Norbert Pardi et al.   CURRENT OPINION IN IMMUNOLOGY

Interactions between Borrelia burgdorferi and ticks

(2020) Cheyne Kurokawa et al.   NATURE REVIEWS MICROBIOLOGY

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

(2020) Lisa A. Jackson et al.   NEW ENGLAND JOURNAL OF MEDICINE

An Ixodes scapularis protein disulfide isomerase contributes to Borrelia burgdorferi colonization of the vector

(2020) Yongguo Cao et al.   INFECTION AND IMMUNITY

Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine

(2020) Cheryl Keech et al.   NEW ENGLAND JOURNAL OF MEDICINE

mRNA as a Transformative Technology for Vaccine Development to Control Infectious Diseases

(2019) Giulietta Maruggi et al.   MOLECULAR THERAPY

A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA

(2019) Markus Baiersdörfer et al.   Molecular Therapy-Nucleic Acids

Borrelia burgdorferi chemotaxis toward tick protein Salp12 contributes to acquisition

(2019) Kristen E. Murfin et al.   Ticks and Tick-Borne Diseases

A Vaccinomics Approach for the Identification of Tick Protective Antigens for the Control of Ixodes ricinus and Dermacentor reticulatus Infestations in Companion Animals

(2019) Marinela Contreras et al.   Frontiers in Physiology

Nucleoside-modified mRNA encoding HSV-2 glycoproteins C, D, and E prevents clinical and subclinical genital herpes

(2019) Sita Awasthi et al.   Science Immunology

Immunological control of ticks and tick-borne diseases that impact cattle health and production

(2018) Consuelo Almazan   Frontiers in Bioscience-Landmark

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses

(2018) Norbert Pardi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

mRNA vaccines — a new era in vaccinology

(2018) Norbert Pardi et al.   NATURE REVIEWS DRUG DISCOVERY

The Blacklegged Tick, Ixodes scapularis : An Increasing Public Health Concern

(2018) Rebecca J. Eisen et al.   TRENDS IN PARASITOLOGY

Sialome diversity of ticks revealed by RNAseq of single tick salivary glands

(2018) Jan Perner et al.   PLoS Neglected Tropical Diseases

Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice

(2018) Yuya Tabakawa et al.   Frontiers in Immunology

Vital Signs: Trends in Reported Vectorborne Disease Cases — United States and Territories, 2004–2016

(2018) Ronald Rosenberg et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Crucial Role for Basophils in Acquired Protective Immunity to Tick Infestation

(2018) Hajime Karasuyama et al.   Frontiers in Physiology

Host-specific expression of Ixodes scapularis salivary genes

(2018) Sukanya Narasimhan et al.   Ticks and Tick-Borne Diseases

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

(2017) Norbert Pardi et al.   NATURE

The Essential Role of Tick Salivary Glands and Saliva in Tick Feeding and Pathogen Transmission

(2017) Ladislav Šimo et al.   Frontiers in Cellular and Infection Microbiology

Ticks, Ixodes scapularis, Feed Repeatedly on White-Footed Mice despite Strong Inflammatory Response: An Expanding Paradigm for Understanding Tick–Host Interactions

(2017) Jennifer M. Anderson et al.   Frontiers in Immunology

Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells

(2017) Gustaf Lindgren et al.   Frontiers in Immunology

Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission

(2016) Cassandra L. Olds et al.   Parasites & Vectors

Human pathogens associated with the blacklegged tick Ixodes scapularis: a systematic review

(2016) Mark P. Nelder et al.   Parasites & Vectors

Ixodes scapularis Tick Saliva Proteins Sequentially Secreted Every 24 h during Blood Feeding

(2016) Tae Kwon Kim et al.   PLoS Neglected Tropical Diseases

Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes

(2015) Norbert Pardi et al.   JOURNAL OF CONTROLLED RELEASE

A sand fly salivary protein vaccine shows efficacy against vector-transmitted cutaneous leishmaniasis in nonhuman primates

(2015) Fabiano Oliveira et al.   Science Translational Medicine

New salivary anti-haemostatics containing protective epitopes from Ornithodoros moubata ticks: Assessment of their individual and combined vaccine efficacy

(2015) Verónica Díaz-Martín et al.   VETERINARY PARASITOLOGY

Basophils have emerged as a key player in immunity

(2014) Hajime Karasuyama et al.   CURRENT OPINION IN IMMUNOLOGY

Lipid-based mRNA vaccine delivery systems

(2014) Patrick Midoux et al.   Expert Review of Vaccines

Cutting Edge: Immunity against a "Silent" Salivary Antigen of the Lyme Vector Ixodes scapularis Impairs Its Ability to Feed

(2014) M. Kotsyfakis et al.   JOURNAL OF IMMUNOLOGY

Factor Xa Activation of Factor V Is of Paramount Importance in Initiating the Coagulation System

(2013) Tim J. Schuijt et al.   CIRCULATION

Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics

(2013) Martin A Maier et al.   MOLECULAR THERAPY

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

(2012) Muthusamy Jayaraman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent

(2011) Tim J. Schuijt et al.   Cell Host & Microbe

Ixodes scapularis salivary gland protein P11 facilitates migration of Anaplasma phagocytophilum from the tick gut to salivary glands

(2011) Lei Liu et al.   EMBO REPORTS

Hemelipoglycoprotein from the ornate sheep tick, Dermacentor marginatus: structural and functional characterization

(2011) Jarmila Dupejova et al.   Parasites & Vectors

Identification and Characterization of Ixodes scapularis Antigens That Elicit Tick Immunity Using Yeast Surface Display

(2011) Tim J. Schuijt et al.   PLoS One

Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks

(2010) Takeshi Wada et al.   JOURNAL OF CLINICAL INVESTIGATION

BBA52 FacilitatesBorrelia burgdorferiTransmission from Feeding Ticks to Murine Hosts

(2010) Manish Kumar et al.   JOURNAL OF INFECTIOUS DISEASES

Tick Histamine Release Factor Is Critical for Ixodes scapularis Engorgement and Transmission of the Lyme Disease Agent

(2010) Jianfeng Dai et al.   PLoS Pathogens

Antibodies against a Tick Protein, Salp15, Protect Mice from the Lyme Disease Agent

(2009) Jianfeng Dai et al.   Cell Host & Microbe

The role of saliva in tick feeding

(2009) Ivo et al.   Frontiers in Bioscience-Landmark

Dermatologic Changes Induced by Repeated Ixodes scapularis Bites and Implications for Prevention of Tick-Borne Infection

(2009) Peter J. Krause et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Salivating for Knowledge: Potential Pharmacological Agents in Tick Saliva

(2008) Joppe W. R Hovius et al.   PLOS MEDICINE