Transition-metal-free electrochemical-induced active C(sp3)-H functionalization

Exploring Electrochemical C(sp3)–H Oxidation for the Late-Stage Methylation of Complex Molecules

(2022) Luiz F. T. Novaes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrochemical Benzylic C–H Functionalization with Isocyanides

(2022) Shanyu Tang et al.   ORGANIC LETTERS

Photochemical and Electrochemical Strategies towards Benzylic C−H Functionalization: A Recent Update

(2021) Monica Oliva et al.   ADVANCED SYNTHESIS & CATALYSIS

Electrochemical Oxidation Enables Regioselective and Scalable α-C(sp3)-H Acyloxylation of Sulfides

(2021) Huamin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organic Electrochemistry: Molecular Syntheses with Potential

(2021) Cuiju Zhu et al.   ACS Central Science

Arene diversification through distal C(sp2)−H functionalization

(2021) Uttam Dutta et al.   SCIENCE

C–H Functionalization via Electrophotocatalysis and Photoelectrochemistry: Complementary Synthetic Approach

(2021) Tomas Hardwick et al.   ACS Sustainable Chemistry & Engineering

Electro-oxidative Intermolecular Allylic C(sp3)–H Aminations

(2021) Yulei Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Electrochemical Oxidative Coupling Between Benzylic C(sp3)–H and N–H of Secondary Amines: Rapid Synthesis of α-Amino α-Aryl Esters

(2021) Yadav Kacharu Nagare et al.   JOURNAL OF ORGANIC CHEMISTRY

C–H Amination via Electrophotocatalytic Ritter-type Reaction

(2021) Tao Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal Nanoparticles as Sustainable Tools for C–N Bond Formation via C–H Activation

(2021) Federica Valentini et al.   MOLECULES

Iodine-mediated electrochemical C(sp3)–H cyclization: the synthesis of quinazolinone-fused N-heterocycles

(2021) Yan Zhang et al.   CHEMICAL COMMUNICATIONS

Electrochemical Synthesis of Benzo[d]imidazole via Intramolecular C(sp3)–H Amination

(2021) An Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Electrochemical Dehydrogenative Acetalization Protection of Alcohols with Tetrahydrofuran

(2021) Raolin Huang et al.   ChemElectroChem

Electrochemical radical C(sp3)–H arylation of xanthenes with electron-rich arenes

(2021) Bin Wei et al.   Organic Chemistry Frontiers

Electrochemical Oxidation of Organic Molecules at Lower Overpotential: Accessing Broader Functional Group Compatibility with Electron−Proton Transfer Mediators

(2020) Fei Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Site-Selective C–H Functionalization via Synergistic Use of Electrochemistry and Transition Metal Catalysis

(2020) Ke-Jin Jiao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Direct Phosphonylation of N-Carbamate-tetrahydroisoquinoline by Convergent Paired Electrolysis

(2020) Stéphane Sengmany et al.   SYNLETT

Electrochemical oxidation-induced etherification via C(sp3)─H/O─H cross-coupling

(2020) Huamin Wang et al.   Science Advances

Transition Metal‐Catalyzed Enantioselective C–H Functionalization via Chiral Transient Directing Group Strategy

(2020) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Scalable Photoelectrochemical Dehydrogenative Cross‐Coupling of Heteroarenes with Aliphatic C−H Bonds

(2020) Pin Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nitrene Transfer and Carbene Transfer in Gold Catalysis

(2020) Long-Wu Ye et al.   CHEMICAL REVIEWS

Transition-Metal-Free Site-Selective γ-C(sp2)–H Monoiodination of Arenes Directed by an Aliphatic Keto Group

(2020) Hong-Li Bian et al.   ORGANIC LETTERS

Iodine-Mediated Electrochemical C(sp2)–H Amination: Switchable Synthesis of Indolines and Indoles

(2020) Kangfei Hu et al.   ORGANIC LETTERS

Metal-free electrochemical oxidative trifluoromethylation/C(sp2) H functionalization of quinolinones

(2020) Chunzhao Xu et al.   TETRAHEDRON LETTERS

Electrochemical Methods for Pd‐catalyzed C–H Functionalization

(2020) Johannes E. Erchinger et al.   Asian Journal of Organic Chemistry

Site‐Selective Electrochemical Benzylic C–H Amination

(2020) Zhong-Wei Hou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Strategic evolution in transition metal-catalyzed directed C–H bond activation and future directions

(2020) Supriya Rej et al.   COORDINATION CHEMISTRY REVIEWS

000Synthesis of new α-aminophosphonates: Evaluation as anti-inflammatory agents and QSAR studies

(2019) Ivan Romero-Estudillo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Electrocatalytic Tandem Synthesis of 1,3-Disubstituted Imidazo[1,5-a]quinolines via Sequential Dual Oxidative C(sp3)−H Amination in Aqueous Medium

(2019) Peng Qian et al.   JOURNAL OF ORGANIC CHEMISTRY

Electrochemically Oxidative C-C Bond Cleavage of Alkylarenes for Anilines Synthesis

(2019) Yeerlan Adeli et al.   ACS Catalysis

Intermolecular dialkylation of alkenes with two distinct C(sp3)─H bonds enabled by synergistic photoredox catalysis and iron catalysis

(2019) Xuan-Hui Ouyang et al.   Science Advances

Electrochemical Cross-Dehydrogenative Coupling of N -Aryl-tetrahydroisoquinolines with Phosphites and Indole

(2019) Wenxia Xie et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Merging Photochemistry with Electrochemistry: Functional-Group Tolerant Electrochemical Amination of C(sp3 )−H Bonds

(2019) Fei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemical and Scalable Dehydrogenative C(sp 3 )−H Amination via Remote Hydrogen Atom Transfer in Batch and Continuous Flow

(2019) Pavlo Nikolaienko et al.   CHEMISTRY-A EUROPEAN JOURNAL

Transient Ligand‐Enabled Transition Metal‐Catalyzed C−H Functionalization

(2019) Ben Niu et al.   ChemSusChem

Intermolecular Anodic Oxidative Cross-Dehydrogenative C(sp3)–N Bond-Coupling Reactions of Xanthenes with Azoles

(2019) Yong-Zheng Yang et al.   ORGANIC LETTERS

Electrocatalytic Three-Component Reaction: Synthesis of Cyanide-Functionalization Imidazo-Fused N-Heterocycles

(2019) Peng Qian et al.   ORGANIC LETTERS

Electrochemical Approach for Direct C–H Phosphonylation of Unprotected Secondary Amine

(2019) Min Huang et al.   ORGANIC LETTERS

Direct Arylation of α-Amino C(sp3 )-H Bonds by Convergent Paired Electrolysis

(2019) Yueyue Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Arene-Limited Nondirected C-H Activation of Arenes

(2018) Philipp Wedi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-Light-Induced Organic Photochemical Reactions via Energy Transfer Pathways

(2018) Wen-Jing Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in radical-based C–N bond formation via photo-/electrochemistry

(2018) Yating Zhao et al.   CHEMICAL SOCIETY REVIEWS

Electrochemical strategies for C–H functionalization and C–N bond formation

(2018) Markus D. Kärkäs   CHEMICAL SOCIETY REVIEWS

Alcohol-based Michaelis–Arbuzov reaction: an efficient and environmentally-benign method for C–P(O) bond formation

(2018) Xiantao Ma et al.   GREEN CHEMISTRY

Anodic benzylic C(sp3)–H amination: unified access to pyrrolidines and piperidines

(2018) Sebastian Herold et al.   GREEN CHEMISTRY

Electrosynthesis of Trisubstituted 2-Oxazolines via Dehydrogenative Cyclization of β-Amino Arylketones

(2018) Huiqiao Wang et al.   ORGANIC LETTERS

Electrochemical Formation of N-Acyloxy Amidyl Radicals and Their Application: Regioselective Intramolecular Amination of sp2 and sp3 C–H Bonds

(2018) Sheng Zhang et al.   ORGANIC LETTERS

Electrocatalytic C–H Activation

(2018) Nicolas Sauermann et al.   ACS Catalysis

Recent Advances in C–H Functionalization Using Electrochemical Transition Metal Catalysis

(2018) Cong Ma et al.   ACS Catalysis

Transient Directing Groups for Transformative C–H Activation by Synergistic Metal Catalysis

(2018) Parthasarathy Gandeepan et al.   Chem

Intermolecular Electrochemical C(sp 3 )-H/N-H Cross-coupling of Xanthenes with N -alkoxyamides: Radical Pathway Mediated by Ferrocene as a Redox Catalyst

(2018) Meng-Ying Lin et al.   ADVANCED SYNTHESIS & CATALYSIS

Recent advances in the sulfonylation of alkenes with the insertion of sulfur dioxide via radical reactions

(2018) Guanyinsheng Qiu et al.   CHEMICAL COMMUNICATIONS

Direct arylation of strong aliphatic C–H bonds

(2018) Ian B. Perry et al.   NATURE

Electrochemical-Oxidation-Induced Site-Selective Intramolecular C(sp3)–H Amination

(2018) Xia Hu et al.   ACS Catalysis

Rh-Catalyzed Removable Directing Group Assisted sp2 or sp3-C-H Bond Functionalization

(2018) Naoto Chatani et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemical Oxidative C(sp3)–H/N‐H cross‐coupling for N‐Mannich Bases with Hydrogen Evolution

(2018) Pan Wang et al.   ChemSusChem

Electrocatalytic Intermolecular C(sp3)–H/N–H Coupling of Methyl N-Heteroaromatics with Amines and Amino Acids: Access to Imidazo-Fused N-Heterocycles

(2018) Peng Qian et al.   ORGANIC LETTERS

Electrocatalytic C–H/N–H Coupling of 2′-Aminoacetophenones for the Synthesis of Isatins

(2017) Peng Qian et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed C(sp3)—H Oxygenation via Electrochemical Oxidation

(2017) Qi-Liang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrocatalytic Dehydrogenative Esterification of Aliphatic Carboxylic Acids: Access to Bioactive Lactones

(2017) Sheng Zhang et al.   ORGANIC LETTERS

Transition-Metal-Free Lactonization of sp2 C–H Bonds with CO2

(2017) Zhen Zhang et al.   ORGANIC LETTERS

Scalable Electrochemical Dehydrogenative Lactonization of C(sp2/sp3)–H Bonds

(2017) Sheng Zhang et al.   ORGANIC LETTERS

Catalytic Asymmetric Electrochemical Oxidative Coupling of Tertiary Amines with Simple Ketones

(2017) Niankai Fu et al.   ORGANIC LETTERS

Palladium-Catalyzed C–H Bond Acetoxylation via Electrochemical Oxidation

(2017) Anuska Shrestha et al.   ORGANIC LETTERS

The Transient Directing Group Strategy: A New Trend in Transition-Metal-Catalyzed C–H Bond Functionalization

(2017) Tatiana Besset et al.   SYNTHESIS-STUTTGART

Electro-oxidative C(sp3)–H Amination of Azoles via Intermolecular Oxidative C(sp3)–H/N–H Cross-Coupling

(2017) Jiwei Wu et al.   ACS Catalysis

Synthesis of meta -Terphenyl-2,2′′-diols by Anodic C−C Cross-Coupling Reactions

(2016) Sebastian Lips et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemical Oxidative C−H/N−H Coupling between γ-Lactams and Anilines

(2016) Ming Gong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Metal-Free Benzylic C−H Amination via Electrochemically Generated Benzylaminosulfonium Ions

(2016) Ryutaro Hayashi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Electrochemical C–H functionalization and subsequent C–S and C–N bond formation: paired electrosynthesis of 3-amino-2-thiocyanato-α,β-unsaturated carbonyl derivatives mediated by bromide ions

(2016) Li-Shuo Kang et al.   GREEN CHEMISTRY

Electrochemically Oxidative α-C–H Functionalization of Ketones: A Cascade Synthesis of α-Amino Ketones Mediated by NH4I

(2016) Sen Liang et al.   JOURNAL OF ORGANIC CHEMISTRY

The Stabilized Cation Pool Method: Metal- and Oxidant-Free Benzylic C–H/Aromatic C–H Cross-Coupling

(2016) Ryutaro Hayashi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Scalable and sustainable electrochemical allylic C–H oxidation

(2016) Evan J. Horn et al.   NATURE

Metal-Free Oxidative Nitration of α-Carbon of Carbonyls Leads to One-Pot Synthesis of Thiohydroximic Acids from Acetophenones

(2016) Shashikant U. Dighe et al.   ORGANIC LETTERS

Microwave-Assisted Synthesis of 2-Aryl-2-oxazolines, 5,6-Dihydro-4H-1,3-oxazines, and 4,5,6,7-Tetrahydro-1,3-oxazepines

(2016) María C. Mollo et al.   ORGANIC LETTERS

Advances in Photocatalysis: A Microreview of Visible Light Mediated Ruthenium and Iridium Catalyzed Organic Transformations

(2016) Kip Teegardin et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Isoindole-1,3-dione derivatives as RSK2 inhibitors: synthesis, molecular docking simulation and SAR analysis

(2016) Wei Zhou et al.   MedChemComm

Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method

(2016) Evan J. Horn et al.   ACS Central Science

Antinociceptive properties of N-Mannich bases derived from 3-substituted pyrrolidine-2,5-dione in the formalin model of persistent pain in mice

(2015) Jolanta Obniska et al.   Pharmacological Reports

Arene C–H functionalisation using a removable/modifiable or a traceless directing group strategy

(2014) Fengzhi Zhang et al.   CHEMICAL SOCIETY REVIEWS

Synthesis and antitumor activities of novel α-aminophosphonate derivatives containing an alizarin moiety

(2014) Man-Yi Ye et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of ABT-267, a Pan-Genotypic Inhibitor of HCV NS5A

(2014) David A. DeGoey et al.   JOURNAL OF MEDICINAL CHEMISTRY

Transition-Metal-Free Oxidative α-C–H Amination of Ketones via a Radical Mechanism: Mild Synthesis of α-Amino Ketones

(2014) Qing Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions

(2013) Heike Schönherr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate

(2013) Romano Di Fabio et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Direct Electrosynthesis of Ketones from Benzylic Methylenes by Electrooxidative CH Activation

(2013) Li Meng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Developing Ligands for Palladium(II)-Catalyzed C–H Functionalization: Intimate Dialogue between Ligand and Substrate

(2013) Keary M. Engle et al.   JOURNAL OF ORGANIC CHEMISTRY

Beyond Directing Groups: Transition-Metal-Catalyzed CH Activation of Simple Arenes

(2012) Nadine Kuhl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidation of aniline with strong and weak oxidants

(2012) I. Yu. Sapurina et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Cross-Dehydrogenative Coupling (CDC): Exploring C−C Bond Formations beyond Functional Group Transformations

(2008) Chao-Jun Li   ACCOUNTS OF CHEMICAL RESEARCH