Voltage-gated sodium channels in diabetic sensory neuropathy: Function, modulation, and therapeutic potential

Cilostazol Ameliorates Peripheral Neuropathic Pain in Streptozotocin-Induced Type I Diabetic Rats

(2022) Kuang-I. Cheng et al.   Frontiers in Pharmacology

Inhibition of sodium conductance by cannabigerol contributes to a reduction of dorsal root ganglion neuron excitability

(2022) Mohammad‐Reza Ghovanloo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Capsaicin, its clinical significance in patients with painful diabetic neuropathy

(2022) Phiwayinkosi V. Dludla et al.   BIOMEDICINE & PHARMACOTHERAPY

Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity

(2021) Mohammad-Reza Ghovanloo et al.   JOURNAL OF GENERAL PHYSIOLOGY

Lipopolysaccharides induce a RAGE-mediated sensitization of sensory neurons and fluid hypersecretion in the upper airways

(2021) Manoj Nair et al.   Scientific Reports

Cannabidiol Inhibition of Murine Primary Nociceptors: Tight Binding to Slow Inactivated States of Nav1.8 Channels

(2021) Han-Xiong Bear Zhang et al.   JOURNAL OF NEUROSCIENCE

The enhancement of TNF-α on TTX resistant NaV current in muscle sensory neurons after femoral artery occlusion

(2020) Qin Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cannabidiol protects against high glucose‐induced oxidative stress and cytotoxicity in cardiac voltage‐gated sodium channels

(2020) Mohamed A. Fouda et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuroprotective effects of ranolazine versus pioglitazone in experimental diabetic neuropathy: Targeting Nav1.7 channels and PPAR-γ

(2020) Shereen E. Elkholy et al.   LIFE SCIENCES

Cannabidiol interactions with voltage-gated sodium channels

(2020) Lily Goodyer Sait et al.   eLife

RAGE signaling is required for AMPA receptor dysfunction in the hippocampus of hyperglycemic mice

(2020) Zeinab Momeni et al.   PHYSIOLOGY & BEHAVIOR

The Role of Voltage-Gated Sodium Channels in Pain Signaling

(2019) David L. Bennett et al.   PHYSIOLOGICAL REVIEWS

Diabetic Neuropathy

(2019) Elina Zakin et al.   SEMINARS IN NEUROLOGY

RAGE-dependent potentiation of TRPV1 currents in sensory neurons exposed to high glucose

(2018) Doris Lam et al.   PLoS One

Diabetic neuropathy and the sensory neuron: New aspects of pathogenesis and their treatment implications

(2018) Masaki Kobayashi et al.   Journal of Diabetes Investigation

Differential Inhibition of Nav1.7 and Neuropathic Pain by Hybridoma-Produced and Recombinant Monoclonal Antibodies that Target Nav1.7

(2018) Sangsu Bang et al.   Neuroscience Bulletin

Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain

(2018) Lubin Chen et al.   Scientific Reports

Inhibitory effects of cannabidiol on voltage-dependent sodium currents

(2018) Mohammad-Reza Ghovanloo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ancillary factors in the treatment of orofacial pain: A topical narrative review

(2018) Marcello Melis et al.   JOURNAL OF ORAL REHABILITATION

Interpreting the functional role of a novel interaction motif in prokaryotic sodium channels

(2017) Altin Sula et al.   JOURNAL OF GENERAL PHYSIOLOGY

The complete structure of an activated open sodium channel

(2017) Altin Sula et al.   Nature Communications

Voltage-Gated Ion Channels in the PNS: Novel Therapies for Neuropathic Pain?

(2016) Gareth R. Tibbs et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Sodium Channel β Subunits: Emerging Targets in Channelopathies

(2015) Heather A. O'Malley et al.   Annual Review of Physiology

Voltage gated sodium channels as drug discovery targets

(2015) Sharan K Bagal et al.   Channels

Voltage-gated sodium channel function and expression in injured and uninjured rat dorsal root ganglia neurons

(2015) Ruoyuan Yin et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications

(2015) Manuel de Lera Ruiz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Efficacy of Inhaled Cannabis on Painful Diabetic Neuropathy

(2015) Mark S. Wallace et al.   JOURNAL OF PAIN

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(2015) Andrew Tan et al.   MOLECULAR MEDICINE

Painful peripheral neuropathy and sodium channel mutations

(2015) Janneke G.J. Hoeijmakers et al.   NEUROSCIENCE LETTERS

Reactive species modify NaV1.8 channels and affect action potentials in murine dorsal root ganglion neurons

(2015) Martin Schink et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

A new look at sodium channel   subunits

(2015) S. Namadurai et al.   Open Biology

Inhibition of Voltage-Gated Na+ Channels by the Synthetic Cannabinoid Ajulemic Acid

(2014) Nilufar Foadi et al.   ANESTHESIA AND ANALGESIA

The Endocannabinoid Anandamide Inhibits Voltage-Gated Sodium Channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 in Xenopus Oocytes

(2014) Dan Okura et al.   ANESTHESIA AND ANALGESIA

A Monoclonal Antibody that Targets a NaV1.7 Channel Voltage Sensor for Pain and Itch Relief

(2014) Jun-Ho Lee et al.   CELL

RAGE mediates the inactivation of nAChRs in sympathetic neurons under high glucose conditions

(2014) Andrew R. Chandna et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The role of TNF-alpha/NF-kappa B pathway on the up-regulation of voltage-gated sodium channel Nav1.7 in DRG neurons of rats with diabetic neuropathy

(2014) Yangliang Huang et al.   NEUROCHEMISTRY INTERNATIONAL

Mechanisms and Management of Diabetic Painful Distal Symmetrical Polyneuropathy

(2013) Solomon Tesfaye et al.   DIABETES CARE

K-685, a TRPV1 Antagonist, Blocks PKC-Sensitized TRPV1 Activation and Improves the Inflammatory Pain in a Rat Complete Freund’s Adjuvant Model

(2013) Yoshiyuki Sugimoto et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Gabapentin reduces allodynia and hyperalgesia in painful diabetic neuropathy rats by decreasing expression level of Nav1.7 and p-ERK1/2 in DRG neurons

(2012) Jun-Long Zhang et al.   BRAIN RESEARCH

Sodium channels, the electrogenisome and the electrogenistat: lessons and questions from the clinic

(2012) Stephen G. Waxman   JOURNAL OF PHYSIOLOGY-LONDON

Diabetic neuropathy: clinical manifestations and current treatments

(2012) Brian C Callaghan et al.   LANCET NEUROLOGY

Reduction of Voltage Gated Sodium Channel Protein in DRG by Vector Mediated miRNA Reduces Pain in Rats with Painful Diabetic Neuropathy

(2012) Munmun Chattopadhyay et al.   Molecular Pain

The NaV1.7 sodium channel: from molecule to man

(2012) Sulayman D. Dib-Hajj et al.   NATURE REVIEWS NEUROSCIENCE

Are Voltage-Gated Sodium Channels on the Dorsal Root Ganglion Involved in the Development of Neuropathic Pain?

(2011) Wei Wang et al.   Molecular Pain

Inhibition of Nav 4 Peptide-Mediated Resurgent Sodium Currents in Nav1.7 Channels by Carbamazepine, Riluzole, and Anandamide

(2011) J. W. Theile et al.   MOLECULAR PHARMACOLOGY

Na+ Channel ? Subunits: Overachievers of the Ion Channel Family

(2011) William J. Brackenbury et al.   Frontiers in Pharmacology

Sodium Channels in Normal and Pathological Pain

(2010) Sulayman D. Dib-Hajj et al.   Annual Review of Neuroscience

Interaction between voltage-gated sodium channels and the neurotoxin, tetrodotoxin

(2010) Chong Hyun Lee et al.   Channels

Diabetic Neuropathies: Update on Definitions, Diagnostic Criteria, Estimation of Severity, and Treatments

(2010) S. Tesfaye et al.   DIABETES CARE

Nav1.7-Ca2+ influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK) and p38 attenuate tau phosphorylation via glycogen synthase kinase-3β: Priming of Nav1.7 gating by ERK and p38

(2010) Takayuki Nemoto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Experimental rodent models of type 2 diabetes: A review

(2010) M.S. Islam et al.   METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY

Single-cell analysis of sodium channel expression in dorsal root ganglion neurons

(2010) Cojen Ho et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Diabetes Depresses Synaptic Transmission in Sympathetic Ganglia by Inactivating nAChRs through a Conserved Intracellular Cysteine Residue

(2010) Verónica Campanucci et al.   NEURON

Dorsal root ganglia sensory neuronal cultures: a tool for drug discovery for peripheral neuropathies

(2009) Giorgia Melli et al.   Expert Opinion on Drug Discovery

Cannabinoids as pharmacotherapies for neuropathic pain: From the bench to the bedside

(2009) Elizabeth J. Rahn et al.   Neurotherapeutics

Cilostazol Protects Endothelial Cells Against Lipopolysaccharide-Induced Apoptosis Through ERK1/2- and P38 MAPK-Dependent Pathways

(2009) Jong-Hoon Lim et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas

(2008) Joel A. Black et al.   ANNALS OF NEUROLOGY

Comparative study of the distribution of the α-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons

(2008) Tetsuo Fukuoka et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Continuous  -Opioid Receptor Activation Reduces Neuronal Voltage-Gated Sodium Channel (NaV1.7) Levels through Activation of Protein Kinase C in Painful Diabetic Neuropathy

(2008) M. Chattopadhyay et al.   JOURNAL OF NEUROSCIENCE

Transcriptional and functional profiles of voltage-gated Na+ channels in injured and non-injured DRG neurons in the SNI model of neuropathic pain

(2007) Temugin Berta et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Glucose neurotoxicity

(2007) David R. Tomlinson et al.   NATURE REVIEWS NEUROSCIENCE