Upcycling the anthracyclines: New mechanisms of action, toxicology, and pharmacology

Recycled Translation: Repurposing Drugs for Stroke

(2022) Samantha E. Spellicy et al.   Translational Stroke Research

Cardiotoxic Effect of Modern Anthracycline Dosing on Left Ventricular Ejection Fraction: A Systematic Review and Meta‐Analysis of Placebo Arms From Randomized Controlled Trials

(2021) Prajith Jeyaprakash et al.   Journal of the American Heart Association

Synthetic (N,N-Dimethyl)doxorubicin Glycosyl Diastereomers to Dissect Modes of Action of Anthracycline Anticancer Drugs

(2021) Dennis P. A. Wander et al.   JOURNAL OF ORGANIC CHEMISTRY

Anthracyclines: biosynthesis, engineering and clinical applications

(2021) Mandy B. Hulst et al.   NATURAL PRODUCT REPORTS

Identification of Potential Inhibitors of SARS-COV-2 Endoribonuclease (EndoU) from FDA Approved Drugs: A Drug Repurposing Approach to find Therapeutics for COID19

(2020) Anshuman Chandra et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Uncoupling DNA damage from chromatin damage to detoxify doxorubicin

(2020) Xiaohang Qiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-based drug repurposing to inhibit the DNA gyrase of Mycobacterium tuberculosis

(2020) Balasubramani G L et al.   BIOCHEMICAL JOURNAL

New insights into the activities and toxicities of the old anticancer drug doxorubicin

(2020) Sabina Y. van der Zanden et al.   FEBS Journal

Doxorubicin and Aclarubicin: Shuffling Anthracycline Glycans for Improved Anticancer Agents

(2020) Dennis P. A. Wander et al.   JOURNAL OF MEDICINAL CHEMISTRY

Omics Technologies to Understand Activation of a Biosynthetic Gene Cluster in Micromonospora sp. WMMB235: Deciphering Keyicin Biosynthesis

(2019) Deepa Acharya et al.   ACS Chemical Biology

Repurposing drugs for treatment of Mycobacterium abscessus: a view to a kill

(2019) Tawanda Gumbo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A High-Throughput Screening Approach To Repurpose FDA-Approved Drugs for Bactericidal Applications against Staphylococcus aureus Small-Colony Variants

(2018) Ryan P. Trombetta et al.   mSphere

Anthracycline cardiotoxicity: an update on mechanisms, monitoring and prevention

(2017) Peter A Henriksen   HEART

ATPase activity of Plasmodium falciparum MLH is inhibited by DNA-interacting ligands and dsRNAs of MLH along with UvrD curtail malaria parasite growth

(2016) Mohammed Tarique et al.   PROTOPLASMA

Eradication of Biofilm-Like Microcolony Structures of Borrelia burgdorferi by Daunomycin and Daptomycin but not Mitomycin C in Combination with Doxycycline and Cefuroxime

(2016) Jie Feng et al.   Frontiers in Microbiology

Multidrug-Resistant Tuberculosis and Extensively Drug-Resistant Tuberculosis

(2015) Kwonjune J. Seung et al.   Cold Spring Harbor Perspectives in Medicine

Case Report: No Response to Liposomal Daunorubicin in a Patient with Drug-Resistant HIV-Associated Visceral Leishmaniasis

(2015) Nicholas J. Gow et al.   PLoS Neglected Tropical Diseases

Identification of new compounds with high activity against stationary phase Borrelia burgdorferi from the NCI compound collection

(2015) Jie Feng et al.   Emerging Microbes & Infections

DNA topoisomerases in mtDNA maintenance and ageing

(2014) Stefan Sobek et al.   EXPERIMENTAL GERONTOLOGY

Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG

(2014) Chathurada Gajadeera et al.   JOURNAL OF ANTIBIOTICS

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation

(2014) Yoshihiko Ichikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Discovering New Treatments for Alzheimer's Disease by Repurposing Approved Medications

(2013) Brian Appleby et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Dexrazoxane for the Prevention of Cardiac Toxicity and Treatment of Extravasation Injury from the Anthracycline Antibiotics

(2012) James H. Doroshow   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Development of nanocapsules bearing doxorubicin for macrophage targeting through the phosphatidylserine ligand: a system for intervention in visceral leishmaniasis

(2012) S. Kansal et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Selected Drugs with Reported Secondary Cell-Differentiating Capacity Prime Latent HIV-1 Infection for Reactivation

(2012) T. Shishido et al.   JOURNAL OF VIROLOGY

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

Huntington's disease: a clinical review

(2011) Raymund A.C. Roos   Orphanet Journal of Rare Diseases

Co-administration of irinotecan decreases the plasma concentration of an active metabolite of amrubicin, amrubicinol in rats

(2009) Yukiko Maeda et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Doxorubicin-induced platelet cytotoxicity: a new contributory factor for doxorubicin-mediated thrombocytopenia

(2009) E.-J. KIM et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS