ATPase activity of Plasmodium falciparum MLH is inhibited by DNA-interacting ligands and dsRNAs of MLH along with UvrD curtail malaria parasite growth

Plasmodium falciparum Bloom homologue, a nucleocytoplasmic protein, translocates in 3′ to 5′ direction and is essential for parasite growth

(2016) Farhana Rahman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Investigating the impacts of DNA binding mode and sequence on thermodynamic quantities and water exchange values for two small molecule drugs

(2016) Rachael M. Kenney et al.   BIOPHYSICAL CHEMISTRY

Morin: A Promising Natural Drug

(2016) Anna Caselli et al.   CURRENT MEDICINAL CHEMISTRY

Inhibition of Plasmodium falciparum proliferation in vitro by double-stranded RNA nanoparticle against malaria topoisomerase II

(2016) Pongsopee Attasart et al.   EXPERIMENTAL PARASITOLOGY

Mutations in the P-Type Cation-Transporter ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone Antimalarials

(2014) Erika L. Flannery et al.   ACS Chemical Biology

Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth

(2014) Mohammed Tarique et al.   BMC BIOCHEMISTRY

In silico screening for Plasmodium falciparum enoyl-ACP reductase inhibitors

(2014) Steffen Lindert et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Emerging importance of mismatch repair components including UvrD helicase and their cross-talk with the development of drug resistance in malaria parasite

(2014) Moaz Ahmad et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Dihydroartemisinin–Piperaquine Failure in Cambodia

(2014) David L. Saunders et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα

(2013) Feng Li et al.   CELL

New aminocoumarin antibiotics as gyrase inhibitors

(2013) Lutz Heide   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Targeting Plasmodium PI(4)K to eliminate malaria

(2013) Case W. McNamara et al.   NATURE

Antimalarial drug discovery — approaches and progress towards new medicines

(2013) Erika L. Flannery et al.   NATURE REVIEWS MICROBIOLOGY

O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation

(2012) Ericka M. Noonan et al.   Integrative Biology

Evolution of Plasmodium falciparum drug resistance: implications for the development and containment of artemisinin resistance

(2012) Toshihiro Mita et al.   JAPANESE JOURNAL OF INFECTIOUS DISEASES

Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling

(2012) Lei-Guo Ming et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Plasmodium falciparum UvrD Helicase Translocates in 3′ to 5′ Direction, Colocalizes with MLH and Modulates Its Activity through Physical Interaction

(2012) Moaz Ahmad et al.   PLoS One

RNA Interference in Protozoan Parasites: Achievements and Challenges

(2011) Nikolay G. Kolev et al.   EUKARYOTIC CELL

Malaria drug resistance is associated with defective DNA mismatch repair

(2011) Meryl A. Castellini et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Plasmodium falciparum MLH is schizont stage specific endonuclease

(2011) Mohammed Tarique et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

DNA topoisomerases in apicomplexan parasites: promising targets for drug discovery

(2010) C. Garcia-Estrada et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Antisense RNA and RNAi in protozoan parasites: Working hard or hardly working?

(2007) Kevin T. Militello et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY