A hepatokine derived from the ER protein CREBH promotes triglyceride metabolism by stimulating lipoprotein lipase activity

The Angiopoietin-Like Protein 3 and 8 Complex Interacts with Lipoprotein Lipase and Induces LPL Cleavage

(2021) Najia Jin et al.   ACS Chemical Biology

Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8

(2021) Kelli L. Sylvers-Davie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Bmal1 regulates production of larger lipoproteins by modulating cAMP‐responsive element‐binding protein H and apolipoprotein AIV

(2021) Xiaoyue Pan et al.   HEPATOLOGY

An updated ANGPTL3-4-8 model as a mechanism of triglyceride partitioning between fat and oxidative tissues

(2021) Ren Zhang et al.   PROGRESS IN LIPID RESEARCH

Direct trafficking pathways from the Golgi apparatus to the plasma membrane

(2020) Danièle Stalder et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia

(2020) Jacqueline S. Dron et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Transcription factors activated through RIP (regulated intramembrane proteolysis) and RAT (regulated alternative translocation)

(2020) Jin Ye   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiopoietin-like protein 8 differentially regulates ANGPTL3 and ANGPTL4 during postprandial partitioning of fatty acids

(2020) Yan Q. Chen et al.   JOURNAL OF LIPID RESEARCH

Lipoprotein Lipase and Its Regulators: An Unfolding Story

(2020) Shuangcheng Alivia Wu et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hepatokines and metabolism: Deciphering communication from the liver

(2020) Sharon O. Jensen-Cody et al.   Molecular Metabolism

Regulation of hepatic autophagy by stress-sensing transcription factor CREBH

(2019) Hyunbae Kim et al.   FASEB JOURNAL

The Role of Mammalian Creb3-Like Transcription Factors in Response to Nutrients

(2019) Haris A. Khan et al.   Frontiers in Genetics

CREB3 Transcription Factors: ER-Golgi Stress Transducers as Hubs for Cellular Homeostasis

(2019) Luciana Sampieri et al.   Frontiers in Cell and Developmental Biology

Promotion of Axon Growth by the Secreted End of a Transcription Factor

(2019) Ethan P. McCurdy et al.   Cell Reports

Prostaglandin F2αFacilitates Hepatic Glucose Production Through CaMKIIγ/p38/FoxO1-Signaling Pathway in Fasting and Obesity

(2018) Yuanyang Wang et al.   DIABETES

ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance

(2017) Jorge F. Haller et al.   JOURNAL OF LIPID RESEARCH

CREBH Maintains Circadian Glucose Homeostasis by Regulating Hepatic Glycogenolysis and Gluconeogenesis

(2017) Hyunbae Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Angiopoietin-like 3 in lipoprotein metabolism

(2017) Sander Kersten   Nature Reviews Endocrinology

Angiopoietin-like 4 directs uptake of dietary fat away from adipose during fasting

(2017) Emily M. Cushing et al.   Molecular Metabolism

ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase

(2017) Xun Chi et al.   Molecular Metabolism

Regulation of lipid metabolism by angiopoietin-like proteins

(2016) Wieneke Dijk et al.   CURRENT OPINION IN LIPIDOLOGY

CREBH Couples Circadian Clock With Hepatic Lipid Metabolism

(2016) Ze Zheng et al.   DIABETES

Identification of the SNARE complex mediating the exocytosis of NMDA receptors

(2016) Yi Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking

(2016) Ren Zhang   Open Biology

Novel CREB3L3 Nonsense Mutation in a Family With Dominant HypertriglyceridemiaSignificance

(2015) Angelo B. Cefalù et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

A lipasin/Angptl8 monoclonal antibody lowers mouse serum triglycerides involving increased postprandial activity of the cardiac lipoprotein lipase

(2015) Zhiyao Fu et al.   Scientific Reports

The GPIHBP1–LPL Complex Is Responsible for the Margination of Triglyceride-Rich Lipoproteins in Capillaries

(2014) Chris N. Goulbourne et al.   Cell Metabolism

Hepatic CREB3L3 Controls Whole-Body Energy Homeostasis and Improves Obesity and Diabetes

(2014) Yoshimi Nakagawa et al.   ENDOCRINOLOGY

Liver-Enriched Transcription Factor CREBH Interacts With Peroxisome Proliferator-Activated Receptor α to Regulate Metabolic Hormone FGF21

(2014) Hyunbae Kim et al.   ENDOCRINOLOGY

Chondrocyte Proliferation Regulated by Secreted Luminal Domain of ER Stress Transducer BBF2H7/CREB3L2

(2013) Atsushi Saito et al.   MOLECULAR CELL

Common variants associated with plasma triglycerides and risk for coronary artery disease

(2013) Ron Do et al.   NATURE GENETICS

Calcium Signaling through CaMKII Regulates Hepatic Glucose Production in Fasting and Obesity

(2012) Lale Ozcan et al.   Cell Metabolism

Hypertriglyceridemia secondary to obesity and diabetes

(2011) Savitha Subramanian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice

(2011) Chunbin Zhang et al.   HEPATOLOGY

The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism

(2011) Jung Hoon Lee et al.   NATURE MEDICINE

GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries

(2010) Brandon S.J. Davies et al.   Cell Metabolism

Regulation of Hepatic Gluconeogenesis by an ER-Bound Transcription Factor, CREBH

(2010) Min-Woo Lee et al.   Cell Metabolism

Cell biology of Ca2+-triggered exocytosis

(2010) Zhiping P Pang et al.   CURRENT OPINION IN CELL BIOLOGY

Identification of a New Functional Domain in Angiopoietin-like 3 (ANGPTL3) and Angiopoietin-like 4 (ANGPTL4) Involved in Binding and Inhibition of Lipoprotein Lipase (LPL)

(2009) E-Chiang Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Hepatocyte nuclear factor 4α is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H

(2008) Jennifer Luebke-Wheeler et al.   HEPATOLOGY