Combined effect of polystyrene microplastics and bisphenol A on the human embryonic stem cells-derived liver organoids: The hepatotoxicity and lipid accumulation

The potential of fluorescent dyes—comparative study of Nile red and three derivatives for the detection of microplastics

(2021) Michael T. Sturm et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

PPARα/RXRα downregulates amino acid catabolism in the liver via interaction with HNF4α promoting its proteasomal degradation

(2021) Sandra Tobón-Cornejo et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A simple, rapid and sensitive method for the simultaneous determination of eighteen environmental phenols in human urine

(2021) Junjie Ao et al.   CHEMOSPHERE

Presence of airborne microplastics in human lung tissue

(2021) Luís Fernando Amato-Lourenço et al.   JOURNAL OF HAZARDOUS MATERIALS

Polystyrene microplastics impact the occurrence of antibiotic resistance genes in earthworms by size-dependent toxic effects

(2021) Guanghui Xu et al.   JOURNAL OF HAZARDOUS MATERIALS

Polystyrene microplastics induce hepatotoxicity and disrupt lipid metabolism in the liver organoids

(2021) Wei Cheng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Detection of Microplastic in Human Placenta and Meconium in a Clinical Setting

(2021) Thorsten Braun et al.   Pharmaceutics

Photoaging enhanced the adverse effects of polyamide microplastics on the growth, intestinal health, and lipid absorption in developing zebrafish

(2021) Xingli Zhang et al.   ENVIRONMENT INTERNATIONAL

Tiered testing of micro- and nanoplastics using intestinal in vitro models to support hazard assessments

(2021) Gerrit Bredeck et al.   ENVIRONMENT INTERNATIONAL

Size-dependent impact of polystyrene microplastics on the toxicity of cadmium through altering neutrophil expression and metabolic regulation in zebrafish larvae

(2021) Li Qin et al.   ENVIRONMENTAL POLLUTION

Environmental microplastic and nanoplastic: Exposure routes and effects on coagulation and the cardiovascular system

(2021) Zachary Lett et al.   ENVIRONMENTAL POLLUTION

Interspecies Differences in Activation of Peroxisome Proliferator-Activated Receptor γ by Pharmaceutical and Environmental Chemicals

(2021) Clémentine Garoche et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Gestational bisphenol A exposure induces fatty liver development in male offspring mice through the inhibition of HNF1b and upregulation of PPARγ

(2020) Zi Long et al.   CELL BIOLOGY AND TOXICOLOGY

Desorption of pharmaceuticals from pristine and aged polystyrene microplastics under simulated gastrointestinal conditions

(2020) Peng Liu et al.   JOURNAL OF HAZARDOUS MATERIALS

Effects of bisphenol A and nanoscale and microscale polystyrene plastic exposure on particle uptake and toxicity in human Caco-2 cells

(2020) Qiangqiang Wang et al.   CHEMOSPHERE

Microplastics release phthalate esters and cause aggravated adverse effects in the mouse gut

(2020) Yongfeng Deng et al.   ENVIRONMENT INTERNATIONAL

Fluorescence Signatures of Dissolved Organic Matter Leached from Microplastics: Polymers and Additives

(2020) Yun Kyung Lee et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Microplastics Reduce Lipid Digestion in Simulated Human Gastrointestinal System

(2020) Huiwen Tan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

High-Fidelity Drug Induced Liver Injury Screen Using Human PSC-derived Organoids

(2020) Tadahiro Shinozawa et al.   GASTROENTEROLOGY

Microplastics and associated contaminants in the aquatic environment: A review on their ecotoxicological effects, trophic transfer, and potential impacts to human health

(2020) Wei Huang et al.   JOURNAL OF HAZARDOUS MATERIALS

Proinflammatory properties and lipid disturbance of polystyrene microplastics in the livers of mice with acute colitis

(2020) Haibin Zheng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Effects of Bisphenol a on cardiovascular disease: An epidemiological study using National Health and nutrition examination survey 2003–2016 and meta-analysis

(2020) Shinje Moon et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Generation of human liver organoids from pluripotent stem cell-derived hepatic endoderms

(2020) Kasem Kulkeaw et al.   PeerJ

Plasticenta: First evidence of microplastics in human placenta

(2020) Antonio Ragusa et al.   ENVIRONMENT INTERNATIONAL

Keap1-Nrf2 pathway up-regulation via hydrogen sulfide mitigates polystyrene microplastics induced-hepatotoxic effects

(2020) Siwen Li et al.   JOURNAL OF HAZARDOUS MATERIALS

Environmental exposure enhances the internalization of microplastic particles into cells

(2020) A. F. R. M. Ramsperger et al.   Science Advances

Endocrine disrupting chemicals: Impacts on human fertility and fecundity during the peri-conception period

(2020) Mark P. Green et al.   ENVIRONMENTAL RESEARCH

Enhanced reproductive toxicities induced by phthalates contaminated microplastics in male mice (Mus musculus)

(2020) Yongfeng Deng et al.   JOURNAL OF HAZARDOUS MATERIALS

Potential human health risks due to environmental exposure to nano- and microplastics and knowledge gaps: A scoping review

(2020) Arifur Rahman et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A targeted review on fate, occurrence, risk and health implications of bisphenol analogues

(2020) Cyrene J. Catenza et al.   CHEMOSPHERE

Insight into the characteristics and sorption behaviors of aged polystyrene microplastics through three type of accelerated oxidation processes

(2020) Xuemin Liu et al.   JOURNAL OF HAZARDOUS MATERIALS

3-D Culture and Endothelial Cells Improve Maturity of Human Pluripotent Stem Cell-Derived Hepatocytes

(2019) Hamisha Ardalani et al.   Acta Biomaterialia

Combined effects of environmental xeno-estrogens within multi-component mixtures: Comparison of in vitro human- and zebrafish-based estrogenicity bioassays

(2019) Hélène Serra et al.   CHEMOSPHERE

Human Consumption of Microplastics

(2019) Kieran D. Cox et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effects of Leachates from UV-Weathered Microplastic in Cell-Based Bioassays

(2019) Christoph D. Rummel et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Generation of expandable human pluripotent stem cell-derived hepatocyte-like liver organoids

(2019) Seon Ju Mun et al.   JOURNAL OF HEPATOLOGY

Detection of Various Microplastics in Human Stool

(2019) Philipp Schwabl et al.   ANNALS OF INTERNAL MEDICINE

Chemical Effect of Bisphenol A on Non-Alcoholic Fatty Liver Disease

(2019) Marcello Dallio et al.   International Journal of Environmental Research and Public Health

Non-alcoholic Fatty Liver Disease Induced by Perinatal Exposure to Bisphenol a Is Associated With Activated mTOR and TLR4/NF-κB Signaling Pathways in Offspring Rats

(2019) Ren Lin et al.   Frontiers in Endocrinology

Combined effect of polystyrene microplastics and dibutyl phthalate on the microalgae Chlorella pyrenoidosa

(2019) Zhaochuan Li et al.   ENVIRONMENTAL POLLUTION

Adsorbed Sulfamethoxazole Exacerbates the Effects of Polystyrene (∼2 μm) on Gut Microbiota and the Antibiotic Resistome of a Soil Collembolan

(2019) Qian Xiang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Large‐scale Production of LGR5‐positive Bipotential Human Liver Stem Cells

(2019) Kerstin Schneeberger et al.   HEPATOLOGY

Identification of adverse outcome pathway related to high-density polyethylene microplastics exposure: Caenorhabditis elegans transcription factor RNAi screening and zebrafish study

(2019) Youngho Kim et al.   JOURNAL OF HAZARDOUS MATERIALS

Combined Exposure to Fructose and Bisphenol A Exacerbates Abnormal Lipid Metabolism in Liver of Developmental Male Rats

(2019) Ren Lin et al.   International Journal of Environmental Research and Public Health

Immunotoxicity of microplastics and two persistent organic pollutants alone or in combination to a bivalve species

(2019) Yu Tang et al.   ENVIRONMENTAL POLLUTION

Polystyrene microplastic exposure disturbs hepatic glycolipid metabolism at the physiological, biochemical, and transcriptomic levels in adult zebrafish

(2019) Yao Zhao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Low doses of BPA induced abnormal mitochondrial fission and hypertrophy in human embryonic stem cell-derived cardiomyocytes via the calcineurin-DRP1 signaling pathway: A comparison between XX and XY cardiomyocytes

(2019) Wei Cheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hepatic ERα accounts for sex differences in the ability to cope with an excess of dietary lipids

(2019) Clara Meda et al.   Molecular Metabolism

Role of bisphenol A as environmental factor in the promotion of non-alcoholic fatty liver disease: in vitro and clinical study

(2018) M. Dallio et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

(2018) Mar Coll et al.   Cell Stem Cell

Urinary concentrations of environmental phenols and their association with type 2 diabetes in a population in Jeddah, Saudi Arabia

(2018) Adela Jing Li et al.   ENVIRONMENTAL RESEARCH

Combined effects of microplastics and chemical contaminants on the organ toxicity of zebrafish ( Danio rerio )

(2018) Sandra Rainieri et al.   ENVIRONMENTAL RESEARCH

Self-assembled liver organoids recapitulate hepatobiliary organogenesis in vitro

(2018) Dipen Vyas et al.   HEPATOLOGY

Evidence that microplastics aggravate the toxicity of organophosphorus flame retardants in mice ( Mus musculus )

(2018) Yongfeng Deng et al.   JOURNAL OF HAZARDOUS MATERIALS

Desorption modeling of hydrophobic organic chemicals from plastic sheets using experimentally determined diffusion coefficients in plastics

(2018) Hwang Lee et al.   MARINE POLLUTION BULLETIN

Interaction of toxic chemicals with microplastics: A critical review

(2018) Fen Wang et al.   WATER RESEARCH

Drosophila HNF4 Directs a Switch in Lipid Metabolism that Supports the Transition to Adulthood

(2018) Gilles Storelli et al.   DEVELOPMENTAL CELL

Rainbow Trout Maintain Intestinal Transport and Barrier Functions Following Exposure to Polystyrene Microplastics

(2018) Giedrė Ašmonaitė et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Endocrine disruption through membrane estrogen receptors and novel pathways leading to rapid toxicological and epigenetic effects

(2018) Cheryl S. Rosenfeld et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hepatic Lipid Accumulation and Nrf2 Expression following Perinatal and Peripubertal Exposure to Bisphenol A in a Mouse Model of Nonalcoholic Liver Disease

(2017) Prajakta C. Shimpi et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications

(2017) Jean-Francois Arnal et al.   PHYSIOLOGICAL REVIEWS

Review of the partitioning of chemicals into different plastics: Consequences for the risk assessment of marine plastic debris

(2016) Isabel A. O'Connor et al.   MARINE POLLUTION BULLETIN

Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα

(2015) Robert C. Bauer et al.   JOURNAL OF CLINICAL INVESTIGATION

Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis

(2015) Rita S. Strakovsky et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Bisphenol-A (BPA), BPA Glucuronide, and BPA Sulfate in Midgestation Umbilical Cord Serum in a Northern and Central California Population

(2013) Roy R. Gerona et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Liver-type fatty acid binding protein interacts with hepatocyte nuclear factor 4α

(2013) Avery L. McIntosh et al.   FEBS LETTERS

Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries

(2013) J. S. Jakobsen et al.   GENOME RESEARCH

Bisphenol A and Peripheral Arterial Disease: Results from the NHANES

(2012) Anoop Shankar et al.   ENVIRONMENTAL HEALTH PERSPECTIVES