GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources

Community Guidelines for GPCR Ligand Bias: IUPHAR Review XX

(2022) Peter Kolb et al.   BRITISH JOURNAL OF PHARMACOLOGY

Multi‐state modeling of G‐protein coupled receptors at experimental accuracy

(2022) Lim Heo et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Common coupling map advances GPCR-G protein selectivity

(2022) Alexander S Hauser et al.   eLife

An online GPCR structure analysis platform

(2021) Albert J. Kooistra et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The G protein database, GproteinDb

(2021) Gáspár Pándy-Szekeres et al.   NUCLEIC ACIDS RESEARCH

The IUPHAR/BPS guide to PHARMACOLOGY in 2022: curating pharmacology for COVID-19, malaria and antibacterials

(2021) Simon D Harding et al.   NUCLEIC ACIDS RESEARCH

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

(2021) Mihaly Varadi et al.   NUCLEIC ACIDS RESEARCH

Computed structures of core eukaryotic protein complexes

(2021) Ian R. Humphreys et al.   SCIENCE

Database resources of the National Center for Biotechnology Information

(2020) Eric W Sayers et al.   NUCLEIC ACIDS RESEARCH

Structure of the class D GPCR Ste2 dimer coupled to two G proteins

(2020) Vaithish Velazhahan et al.   NATURE

GPCRdb in 2021: integrating GPCR sequence, structure and function

(2020) Albert J Kooistra et al.   NUCLEIC ACIDS RESEARCH

RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences

(2020) Stephen K Burley et al.   NUCLEIC ACIDS RESEARCH

UniProt: the universal protein knowledgebase in 2021

(2020) et al.   NUCLEIC ACIDS RESEARCH

An online resource for GPCR structure determination and analysis

(2019) Christian Munk et al.   NATURE METHODS

Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

(2019) Simon R. Foster et al.   CELL

Pharmacogenomics of GPCR Drug Targets

(2018) Alexander S. Hauser et al.   CELL

ChEMBL: towards direct deposition of bioassay data

(2018) David Mendez et al.   NUCLEIC ACIDS RESEARCH

Trends in GPCR drug discovery: new agents, targets and indications

(2017) Alexander S. Hauser et al.   NATURE REVIEWS DRUG DISCOVERY

GPCRdb in 2018: adding GPCR structure models and ligands

(2017) Gáspár Pándy-Szekeres et al.   NUCLEIC ACIDS RESEARCH

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

GPCRdb: the G protein-coupled receptor database - an introduction

(2016) C Munk et al.   BRITISH JOURNAL OF PHARMACOLOGY

Integrating structural and mutagenesis data to elucidate GPCR ligand binding

(2016) Christian Munk et al.   CURRENT OPINION IN PHARMACOLOGY

The FAIR Guiding Principles for scientific data management and stewardship

(2016) Mark D. Wilkinson et al.   Scientific Data

GPCRdb: an information system for G protein-coupled receptors

(2015) Vignir Isberg et al.   NUCLEIC ACIDS RESEARCH

Generic GPCR residue numbers – aligning topology maps while minding the gaps

(2015) Vignir Isberg et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

GPCRDB: an information system for G protein-coupled receptors

(2013) Vignir Isberg et al.   NUCLEIC ACIDS RESEARCH

UniChem: a unified chemical structure cross-referencing and identifier tracking system

(2013) Jon Chambers et al.   Journal of Cheminformatics