Chlorpyrifos, permethrin and cyfluthrin effect on cell survival, permeability, and tight junction in an in-vitro model of the human blood-brain barrier (BBB)

Delivery of Thyronamines (TAMs) to the Brain: A Preliminary Study

(2021) Nicoletta di Leo et al.   MOLECULES

Exposure to Sub-Lethal Doses of Permethrin Is Associated with Neurotoxicity: Changes in Bioenergetics, Redox Markers, Neuroinflammation and Morphology

(2021) Teresita Guadalupe López-Aceves et al.   Toxics

A face-to-face comparison of claudin-5 transduced human brain endothelial (hCMEC/D3) cells with porcine brain endothelial cells as blood–brain barrier models for drug transport studies

(2020) Birthe Gericke et al.   Fluids and Barriers of the CNS

Associations of prenatal and childhood chlorpyrifos exposure with Neurodevelopment of 3-year-old children

(2019) Jianqiu Guo et al.   ENVIRONMENTAL POLLUTION

Gut microbiome: An intermediary to neurotoxicity

(2019) Joseph L. Dempsey et al.   NEUROTOXICOLOGY

Bioavailability and nervous tissue distribution of pyrethroid insecticide cyfluthrin in rats

(2018) José-Luis Rodríguez et al.   FOOD AND CHEMICAL TOXICOLOGY

Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy

(2018) Ralf G. Rempe et al.   JOURNAL OF NEUROSCIENCE

Drug-drug interactions of P-gp substrates unrelated to CYP metabolism

(2018) Yumiko Akamine et al.   CURRENT DRUG METABOLISM

Age-Dependency of Blood-Brain Barrier Penetration by cis- and trans-Permethrin in the Rat

(2018) Tanzir Mortuza et al.   DRUG METABOLISM AND DISPOSITION

Developmental neurotoxicity of the organophosphorus insecticide chlorpyrifos: from clinical findings to preclinical models and potential mechanisms

(2017) Richard D. Burke et al.   JOURNAL OF NEUROCHEMISTRY

A Critical View on In Vitro Analysis of P-glycoprotein (P-gp) Transport Kinetics

(2017) Lasse Saaby et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Beta-cyfluthrin induced neurobehavioral impairments in adult rats

(2016) Farah Syed et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Development of a permeability-limited model of the human brain and cerebrospinal fluid (CSF) to integrate known physiological and biological knowledge: Estimating time varying CSF drug concentrations and their variability using in vitro data

(2016) Lu Gaohua et al.   Drug Metabolism and Pharmacokinetics

Effects of exposure to pyrethroid cyfluthrin on serotonin and dopamine levels in brain regions of male rats

(2016) J.L. Rodríguez et al.   ENVIRONMENTAL RESEARCH

Plasma protein binding limits the blood brain barrier permeation of the pyrethroid insecticide, deltamethrin

(2016) Manoj Amaraneni et al.   TOXICOLOGY LETTERS

The Three Rs of Animal Research: What they Mean for the Institutional Animal Care and Use Committee and Why

(2015) Howard J. Curzer et al.   SCIENCE AND ENGINEERING ETHICS

In Vitro Models of the Blood–Brain Barrier for the Study of Drug Delivery to the Brain

(2014) Imola Wilhelm et al.   MOLECULAR PHARMACEUTICS

Chlorpyrifos PBPK/PD model for multiple routes of exposure

(2014) Torka S. Poet et al.   XENOBIOTICA

Blood–brain barrier structure and function and the challenges for CNS drug delivery

(2013) N. Joan Abbott   JOURNAL OF INHERITED METABOLIC DISEASE

Quantitative Atlas of Blood–Brain Barrier Transporters, Receptors, and Tight Junction Proteins in Rats and Common Marmoset

(2013) Yutaro Hoshi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Dynamic properties of the tight junction barrier

(2012) Christopher R. Weber   Annals of the New York Academy of Sciences

Chlorpyrifos and neurodevelopmental effects: a literature review and expert elicitation on research and policy

(2012) Margaret Saunders et al.   Environmental Health

Transient alterations of the blood-brain barrier tight junction and receptor potential channel gene expression by chlorpyrifos

(2012) Wen Li et al.   JOURNAL OF APPLIED TOXICOLOGY

A Pharmacokinetic Model of cis- and trans-Permethrin Disposition in Rats and Humans With Aggregate Exposure Application

(2012) Rogelio Tornero-Velez et al.   TOXICOLOGICAL SCIENCES

Specific Role of Tight Junction Proteins Claudin-5, Occludin, and ZO-1 of the Blood–Brain Barrier in a Focal Cerebral Ischemic Insult

(2011) Haixia Jiao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The impact of P-glycoprotein mediated efflux on absorption of 11 sedating and less-sedating antihistamines using Caco-2 monolayers

(2011) Andrew Crowe et al.   XENOBIOTICA

Evidence for a separate mechanism of toxicity for the Type I and the Type II pyrethroid insecticides

(2009) Charles B. Breckenridge et al.   NEUROTOXICOLOGY

The Effect of Plasma Lipids on the Pharmacokinetics of Chlorpyrifos and the Impact on Interpretation of Blood Biomonitoring Data

(2009) Ezra R. Lowe et al.   TOXICOLOGICAL SCIENCES

Review of the Toxicology of Chlorpyrifos With an Emphasis on Human Exposure and Neurodevelopment

(2008) David L. Eaton et al.   CRITICAL REVIEWS IN TOXICOLOGY

In Vitro Metabolism of Pyrethroid Pesticides by Rat and Human Hepatic Microsomes and Cytochrome P450 Isoforms

(2008) E. J. Scollon et al.   DRUG METABOLISM AND DISPOSITION

The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies

(2008) Birk Poller et al.   JOURNAL OF NEUROCHEMISTRY