[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

Detecting primary aldosteronism in Australian primary care: a prospective study

(2022) Renata Libianto et al.   MEDICAL JOURNAL OF AUSTRALIA

Somatic mutations in adrenals from patients with primary aldosteronism not cured after adrenalectomy suggest common pathogenic mechanisms between unilateral and bilateral disease

(2021) Inès Hacini et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Single-Center Prospective Cohort Study on the Histopathology, Genotype, and Postsurgical Outcomes of Patients With Primary Aldosteronism

(2021) Lucie S. Meyer et al.   HYPERTENSION

Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

(2021) Junhua Zhou et al.   NATURE GENETICS

Subtypes of Histopathologically Classical Aldosterone-Producing Adenomas Yield Various Transcriptomic Signaling and Outcomes

(2021) Vin-Cent Wu et al.   HYPERTENSION

The Unrecognized Prevalence of Primary Aldosteronism

(2020) Jenifer M. Brown et al.   ANNALS OF INTERNAL MEDICINE

Genetic, Cellular, and Molecular Heterogeneity in Adrenals With Aldosterone-Producing Adenoma

(2020) Kelly De Sousa et al.   HYPERTENSION

Cosyntropin stimulation in adrenal vein sampling improves the judgment of successful adrenal vein catheterization and outcome prediction for primary aldosteronism

(2020) Midori Yatabe et al.   HYPERTENSION RESEARCH

International histopathology consensus for unilateral primary aldosteronism

(2020) Tracy Ann Williams et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Biochemical, Histopathological, and Genetic Characterization of Posture-Responsive and Unresponsive APAs

(2020) Zeng Guo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

(2020) Irina Bancos et al.   Lancet Diabetes & Endocrinology

Functional imaging with 11C-metomidate PET for subtype diagnosis in primary aldosteronism

(2020) Minna Soinio et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Repeat Adrenal Vein Sampling in Aldosteronism: Reproducibility and Interpretation of Persistently Discordant Results

(2020) Gregory A Kline et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Primary Aldosteronism Surgical Outcome Score for the Prediction of Clinical Outcomes After Adrenalectomy for Unilateral Primary Aldosteronism

(2019) Jacopo Burrello et al.   ANNALS OF SURGERY

Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks

(2019) Kazutaka Nanba et al.   HYPERTENSION

18-Oxocortisol Synthesis in Aldosterone-Producing Adrenocortical Adenoma and Significance of KCNJ5 Mutation Status

(2019) Yuta Tezuka et al.   HYPERTENSION

RNA Sequencing Provides Novel Insights into the Transcriptome of Aldosterone Producing Adenomas

(2019) Samuel Backman et al.   Scientific Reports

Adrenal venous sampling: cosyntropin stimulation or not?

(2019) Jaap Deinum et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Renal Outcomes in Medically and Surgically Treated Primary Aldosteronism

(2018) Gregory L. Hundemer et al.   HYPERTENSION

CLCN2 chloride channel mutations in familial hyperaldosteronism type II

(2018) Ute I. Scholl et al.   NATURE GENETICS

A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism

(2018) Fabio L. Fernandes-Rosa et al.   NATURE GENETICS

Primary aldosteronism: making sense of partial data sets from failed adrenal venous sampling-suppression of adrenal aldosterone production can be used in clinical decision making

(2018) Veljko Strajina et al.   SURGERY

Cardiometabolic outcomes and mortality in medically treated primary aldosteronism: a retrospective cohort study

(2018) Gregory L Hundemer et al.   Lancet Diabetes & Endocrinology

Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis

(2018) Silvia Monticone et al.   Lancet Diabetes & Endocrinology

Incidence of Atrial Fibrillation and Mineralocorticoid Receptor Activity in Patients With Medically and Surgically Treated Primary Aldosteronism

(2018) Gregory L. Hundemer et al.   JAMA Cardiology

Radiation exposure of adrenal vein sampling: a German Multicenter Study

(2018) C T Fuss et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Cellular and Genetic Causes of Idiopathic Hyperaldosteronism

(2018) Kei Omata et al.   HYPERTENSION

Glucocorticoid activation by 11β-hydroxysteroid dehydrogenase enzymes in relation to inflammation and glycaemic control in chronic kidney disease: A cross-sectional study

(2018) Michael S. Sagmeister et al.   CLINICAL ENDOCRINOLOGY

Disordered CYP11B2 Expression in Primary Aldosteronism

(2017) Celso Gomez-Sanchez et al.   HORMONE AND METABOLIC RESEARCH

Calneuron 1 Increased Ca2+in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing AdenomaNovelty and Significance

(2017) Kazuhiro Kobuke et al.   HYPERTENSION

Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin)Novelty and Significance

(2017) Ada Ee Der Teo et al.   HYPERTENSION

Prevalence and Clinical Manifestations of Primary Aldosteronism Encountered in Primary Care Practice

(2017) Silvia Monticone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort

(2017) Tracy A Williams et al.   Lancet Diabetes & Endocrinology

Mass Spectrometry-Based Adrenal and Peripheral Venous Steroid Profiling for Subtyping Primary Aldosteronism

(2016) G. Eisenhofer et al.   CLINICAL CHEMISTRY

A Novel CYP11B2-Specific Imaging Agent for Detection of Unilateral Subtypes of Primary Aldosteronism

(2016) Tsutomu Abe et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Study Heterogeneity and Estimation of Prevalence of Primary Aldosteronism: A Systematic Review and Meta-Regression Analysis

(2016) Sabine C. Käyser et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline

(2016) John W. Funder et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Primary aldosteronism as a public health issue

(2016) John W Funder   Lancet Diabetes & Endocrinology

Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas

(2015) Tobias Åkerström et al.   ENDOCRINE-RELATED CANCER

Genotype-Specific Steroid Profiles Associated With Aldosterone-Producing AdenomasNovelty and Significance

(2015) Tracy Ann Williams et al.   HYPERTENSION

Comparison of Cardiovascular Complications in Patients with and without KCNJ5 Gene Mutations Harboring Aldosterone-producing Adenomas

(2015) Takumi Kitamoto et al.   Journal of Atherosclerosis and Thrombosis

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

(2015) Bryan Williams et al.   LANCET

Immunohistochemical, genetic and clinical characterization of sporadic aldosterone-producing adenomas

(2015) Silvia Monticone et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands

(2015) Koshiro Nishimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Outcome of Adrenal Vein Sampling Performed During Concurrent Mineralocorticoid Receptor Antagonist Therapy

(2014) Matthias Haase et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Development of a Novel Nomogram to Predict Hypertension Cure After Laparoscopic Adrenalectomy in Patients With Primary Aldosteronism

(2014) Takanobu Utsumi et al.   WORLD JOURNAL OF SURGERY

Aldosterone mediates its rapid effects in vascular endothelial cells through GPER activation

(2013) Robert Gros et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

An Expert Consensus Statement on Use of Adrenal Vein Sampling for the Subtyping of Primary Aldosteronism

(2013) Gian Paolo Rossi et al.   HYPERTENSION

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension

(2013) Elena A B Azizan et al.   NATURE GENETICS

Somatic Mutations Affecting the Selectivity Filter of KCNJ5 Are Frequent in 2 Large Unselected Collections of Adrenal Aldosteronomas

(2012) Elena A.B. Azizan et al.   HYPERTENSION

Prevalence, Clinical, and Molecular Correlates of KCNJ5 Mutations in Primary Aldosteronism

(2012) Sheerazed Boulkroun et al.   HYPERTENSION

Quantitation of aldosterone in human plasma by ultra high performance liquid chromatography tandem mass spectrometry

(2012) Edward Hinchliffe et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

18-Hydroxycorticosterone, 18-Hydroxycortisol, and 18-Oxocortisol in the Diagnosis of Primary Aldosteronism and Its Subtypes

(2012) Paolo Mulatero et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Microarray, qPCR, andKCNJ5Sequencing of Aldosterone-Producing Adenomas Reveal Differences in Genotype and Phenotype between Zona Glomerulosa- and Zona Fasciculata-Like Tumors

(2012) Elena A. B. Azizan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

GPR30, Mineralocorticoid Receptors, and the Rapid Vascular Effects of Aldosterone

(2011) John W. Funder   HYPERTENSION

Evaluation of the Sensitivity and Specificity of11C-Metomidate Positron Emission Tomography (PET)-CT for Lateralizing Aldosterone Secretion by Conn's Adenomas

(2011) Timothy J. Burton et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Teratocarcinoma-Derived Growth Factor-1 Is Upregulated in Aldosterone-Producing Adenomas and Increases Aldosterone Secretion and Inhibits Apoptosis In Vitro

(2010) Tracy A. Williams et al.   HYPERTENSION

Adrenocortical Zonation in Humans under Normal and Pathological Conditions

(2010) Koshiro Nishimoto et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Aldosteronoma Resolution Score

(2009) Rasa Zarnegar et al.   ANNALS OF SURGERY

What are the keys to successful adrenal venous sampling (AVS) in patients with primary aldosteronism?

(2009) William F. Young et al.   CLINICAL ENDOCRINOLOGY