Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks

Age-Related Blood Pressure Sensitivity to Aldosterone in Blacks and WhitesNovelty and Significance

(2018) Wanzhu Tu et al.   HYPERTENSION

CLCN2 chloride channel mutations in familial hyperaldosteronism type II

(2018) Ute I. Scholl et al.   NATURE GENETICS

A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism

(2018) Fabio L. Fernandes-Rosa et al.   NATURE GENETICS

Cellular and Genetic Causes of Idiopathic Hyperaldosteronism

(2018) Kei Omata et al.   HYPERTENSION

Targeted Molecular Characterization of Aldosterone-Producing Adenomas in White Americans

(2018) Kazutaka Nanba et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

(2017) Paul K. Whelton et al.   HYPERTENSION

The prevalence of CTNNB1 mutations in primary aldosteronism and consequences for clinical outcomes

(2017) Vin-Cent Wu et al.   Scientific Reports

Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort

(2017) Tracy A Williams et al.   Lancet Diabetes & Endocrinology

GNAS mutations in adrenal aldosterone-producing adenomas [Rapid Communication]

(2016) Yasuyo Nakajima et al.   ENDOCRINE JOURNAL

Double adrenocortical adenomas harboring independentKCNJ5andPRKACAsomatic mutations

(2016) Kazutaka Nanba et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Molecular Heterogeneity in Aldosterone-Producing Adenomas

(2016) Kazutaka Nanba et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

PRKACASomatic Mutations Are Rare Findings in Aldosterone-Producing Adenomas

(2016) Yara Rhayem et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline

(2016) John W. Funder et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Activating mutations in CTNNB1 in aldosterone producing adenomas

(2016) Tobias Åkerström et al.   Scientific Reports

Regulation of aldosterone secretion by Cav1.3

(2016) Catherine B. Xie et al.   Scientific Reports

Novel somatic mutations in primary hyperaldosteronism are related to the clinical, radiological and pathological phenotype

(2015) Ute I. Scholl et al.   CLINICAL ENDOCRINOLOGY

Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas

(2015) Tobias Åkerström et al.   ENDOCRINE-RELATED CANCER

Pathogenesis of Adrenal Aldosterone-Producing Adenomas Carrying Mutations of the Na+/K+-ATPase

(2015) J. Stindl et al.   ENDOCRINOLOGY

Is there a role for segmental adrenal venous sampling and adrenal sparing surgery in patients with primary aldosteronism?

(2015) Fumitoshi Satoh et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

KCNJ5Mutations Are the Most Frequent Genetic Alteration in Primary Aldosteronism

(2015) Tracy A. Williams et al.   HYPERTENSION

Clinical Characteristics of Somatic Mutations in Chinese Patients With Aldosterone-Producing AdenomaNovelty and Significance

(2015) Fang-Fang Zheng et al.   HYPERTENSION

Comparison of Cardiovascular Complications in Patients with and without KCNJ5 Gene Mutations Harboring Aldosterone-producing Adenomas

(2015) Takumi Kitamoto et al.   Journal of Atherosclerosis and Thrombosis

Prevalence and Characterization of Somatic Mutations in Chinese Aldosterone-Producing Adenoma Patients

(2015) Baojun Wang et al.   MEDICINE

Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands

(2015) Koshiro Nishimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism

(2015) Ute I Scholl et al.   eLife

Racial Differences in Sensitivity of Blood Pressure to Aldosterone

(2014) Wanzhu Tu et al.   HYPERTENSION

Genetic Spectrum and Clinical Correlates of Somatic Mutations in Aldosterone-Producing Adenoma

(2014) Fabio Luiz Fernandes-Rosa et al.   HYPERTENSION

A Novel KCNJ5-insT149 Somatic Mutation Close to, but Outside, the Selectivity Filter Causes Resistant Hypertension by Loss of Selectivity for Potassium

(2014) Maniselvan Kuppusamy et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Adrenal Nodularity and Somatic Mutations in Primary Aldosteronism: One Node Is the Culprit?

(2014) T. Dekkers et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Constitutive Activation of PKA Catalytic Subunit in Adrenal Cushing's Syndrome

(2014) Felix Beuschlein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome

(2014) Y. Sato et al.   SCIENCE

2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults

(2013) Paul A. James et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension

(2013) Elena A B Azizan et al.   NATURE GENETICS

Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism

(2013) Ute I Scholl et al.   NATURE GENETICS

Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension

(2013) Felix Beuschlein et al.   NATURE GENETICS

Prevalence, Clinical, and Molecular Correlates of KCNJ5 Mutations in Primary Aldosteronism

(2012) Sheerazed Boulkroun et al.   HYPERTENSION

Expression and Mutations of KCNJ5 mRNA in Japanese Patients with Aldosterone-Producing Adenomas

(2012) Ryo Taguchi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Microarray, qPCR, andKCNJ5Sequencing of Aldosterone-Producing Adenomas Reveal Differences in Genotype and Phenotype between Zona Glomerulosa- and Zona Fasciculata-Like Tumors

(2012) Elena A. B. Azizan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Aldosterone contributes to elevated left ventricular mass in black boys

(2012) Diana G. Murro et al.   PEDIATRIC NEPHROLOGY

K+ Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension

(2011) M. Choi et al.   SCIENCE

Adrenocortical Zonation in Humans under Normal and Pathological Conditions

(2010) Koshiro Nishimoto et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM