Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline

Tau biomarkers in Alzheimer's disease: towards implementation in clinical practice and trials

(2022) Rik Ossenkoppele et al.   LANCET NEUROLOGY

Divergent Cortical Tau Positron Emission Tomography Patterns Among Patients With Preclinical Alzheimer Disease

(2022) Christina B. Young et al.   JAMA Neurology

Association of Elevated Amyloid and Tau Positron Emission Tomography Signal With Near-Term Development of Alzheimer Disease Symptoms in Older Adults Without Cognitive Impairment

(2022) Cherie Strikwerda-Brown et al.   JAMA Neurology

Clinical validity of increased cortical uptake of [18F]flortaucipir on PET as a biomarker for Alzheimer’s disease in the context of a structured 5-phase biomarker development framework

(2021) E. E. Wolters et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

2020 update on the clinical validity of cerebrospinal fluid amyloid, tau, and phospho-tau as biomarkers for Alzheimer’s disease in the context of a structured 5-phase development framework

(2021) A. Leuzy et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Visualization of neurofibrillary tangle maturity in Alzheimer's disease: A clinicopathologic perspective for biomarker research

(2021) Christina M. Moloney et al.   Alzheimers & Dementia

Early stages of tau pathology and its associations with functional connectivity, atrophy and memory

(2021) David Berron et al.   BRAIN

Clinical diagnosis of Alzheimer's disease: recommendations of the International Working Group

(2021) Bruno Dubois et al.   LANCET NEUROLOGY

Prediction of future Alzheimer’s disease dementia using plasma phospho-tau combined with other accessible measures

(2021) Sebastian Palmqvist et al.   NATURE MEDICINE

Tau-PET and in vivo Braak-staging as prognostic markers of future cognitive decline in cognitively normal to demented individuals

(2021) Davina Biel et al.   Alzheimers Research & Therapy

Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease

(2021) Rik Ossenkoppele et al.   JAMA Neurology

Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study

(2021) Shi-Dong Chen et al.   Translational Psychiatry

Alzheimer’s disease profiled by fluid and imaging markers: tau PET best predicts cognitive decline

(2021) Marco Bucci et al.   MOLECULAR PSYCHIATRY

Baseline [18F]GTP1 tau PET imaging is associated with subsequent cognitive decline in Alzheimer’s disease

(2021) Edmond Teng et al.   Alzheimers Research & Therapy

Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer Disease

(2021) Antoine Leuzy et al.   JAMA Neurology

Plasma P-tau181 in Alzheimer’s disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer’s dementia

(2020) Shorena Janelidze et al.   NATURE MEDICINE

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

(2020) Nicolas R. Barthélemy et al.   NATURE MEDICINE

Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes

(2020) Adam S. Fleisher et al.   JAMA Neurology

Diagnostic Performance of RO948 F 18 Tau Positron Emission Tomography in the Differentiation of Alzheimer Disease From Other Neurodegenerative Disorders

(2020) Antoine Leuzy et al.   JAMA Neurology

18F-MK-6240 PET for early and late detection of neurofibrillary tangles

(2020) Tharick A Pascoal et al.   BRAIN

Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults

(2020) Shama Karanth et al.   JAMA Neurology

Genetic variants and functional pathways associated with resilience to Alzheimer’s disease

(2020) Logan Dumitrescu et al.   BRAIN

Associations between tau, Aβ, and cortical thickness with cognition in Alzheimer disease

(2019) Rik Ossenkoppele et al.   NEUROLOGY

Tau PET in autosomal dominant Alzheimer’s disease: relationship with cognition, dementia and other biomarkers

(2019) Brian A Gordon et al.   BRAIN

A multicentre longitudinal study of flortaucipir (18F) in normal ageing, mild cognitive impairment and Alzheimer’s disease dementia

(2019) Michael J Pontecorvo et al.   BRAIN

Progressive tau accumulation in Alzheimer’s disease: two-year follow-up study

(2019) Hanna Cho et al.   JOURNAL OF NUCLEAR MEDICINE

Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia

(2019) Clifford R. Jack et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Determining clinically meaningful decline in preclinical Alzheimer disease

(2019) Philip S. Insel et al.   NEUROLOGY

Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease

(2019) Bernard J. Hanseeuw et al.   JAMA Neurology

Estimation of lifetime risks of Alzheimer's disease dementia using biomarkers for preclinical disease

(2018) Ron Brookmeyer et al.   Alzheimers & Dementia

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Cognitive and neuroimaging features and brain β-amyloidosis in individuals at risk of Alzheimer's disease (INSIGHT-preAD): a longitudinal observational study

(2018) Bruno Dubois et al.   LANCET NEUROLOGY

Subjective Cognitive Impairment Cohort (SCIENCe): study design and first results

(2018) Rosalinde E. R. Slot et al.   Alzheimers Research & Therapy

Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons

(2017) Michael C. Donohue et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Harvard Aging Brain Study: Dataset and accessibility

(2017) Alexander Dagley et al.   NEUROIMAGE

Practice guideline update summary: Mild cognitive impairment

(2017) Ronald C. Petersen et al.   NEUROLOGY

Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease

(2016) Rik Ossenkoppele et al.   BRAIN

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

(2016) Clifford R. Jack et al.   NEUROLOGY

PET Imaging of Tau Deposition in the Aging Human Brain

(2016) Michael Schöll et al.   NEURON

Tau positron emission tomographic imaging in aging and early Alzheimer disease

(2015) Keith A. Johnson et al.   ANNALS OF NEUROLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

The Preclinical Alzheimer Cognitive Composite

(2014) Michael C. Donohue et al.   JAMA Neurology

Is Verbal Episodic Memory in Elderly with Amyloid Deposits Preserved Through Altered Neuronal Function?

(2013) Rik Ossenkoppele et al.   CEREBRAL CORTEX

Effect of lifestyle activities on alzheimer disease biomarkers and cognition

(2012) Prashanthi Vemuri et al.   ANNALS OF NEUROLOGY

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The Mayo Clinic Study of Aging: Design and Sampling, Participation, Baseline Measures and Sample Characteristics

(2008) Rosebud O. Roberts et al.   NEUROEPIDEMIOLOGY