A multicentre longitudinal study of flortaucipir (18F) in normal ageing, mild cognitive impairment and Alzheimer’s disease dementia

Longitudinal tau PET in ageing and Alzheimer’s disease

(2018) Clifford R Jack et al.   BRAIN

In vivo characterization and quantification of neurofibrillary tau PET radioligand [18F]MK-6240 in humans from Alzheimer’s disease dementia to young controls

(2018) Tobey J Betthauser et al.   JOURNAL OF NUCLEAR MEDICINE

First in-human PET study of 3 novel tau radiopharmaceuticals: [11C]RO6924963, [11C]RO6931643, and [18F]RO6958948

(2018) Dean F. Wong et al.   JOURNAL OF NUCLEAR MEDICINE

Early Clinical PET Imaging Results with the Novel PHF-Tau Radioligand [F18]-T808

(2018) David T. Chien et al.   JOURNAL OF ALZHEIMERS DISEASE

Quantitation of PET signal as an adjunct to visual interpretation of florbetapir imaging

(2017) Michael J. Pontecorvo et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Flortaucipir F 18 Quantitation Using Parametric Estimation of Reference Signal Intensity

(2017) Sudeepti Southekal et al.   JOURNAL OF NUCLEAR MEDICINE

Preclinical Evaluation of 18 F-JNJ64349311, a Novel PET Tracer for Tau Imaging

(2017) Lieven Declercq et al.   JOURNAL OF NUCLEAR MEDICINE

Test–Retest Reproducibility for the Tau PET Imaging Agent Flortaucipir F 18

(2017) Michael D. Devous et al.   JOURNAL OF NUCLEAR MEDICINE

Tau PET imaging: present and future directions

(2017) Laure Saint-Aubert et al.   Molecular Neurodegeneration

Excessive tau accumulation in the parieto-occipital cortex characterizes early-onset Alzheimer's disease

(2017) Hanna Cho et al.   NEUROBIOLOGY OF AGING

Aβ-amyloid and Tau Imaging in Dementia

(2017) Victor L. Villemagne et al.   SEMINARS IN NUCLEAR MEDICINE

[18F]AV-1451 tau-PET uptake does correlate with quantitatively measured 4R-tau burden in autopsy-confirmed corticobasal degeneration

(2016) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Multimodal evaluation demonstrates in vivo 18F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration

(2016) Corey T. McMillan et al.   ACTA NEUROPATHOLOGICA

Phase 3 solanezumab trials: Secondary outcomes in mild Alzheimer's disease patients

(2016) Eric R. Siemers et al.   Alzheimers & Dementia

In vivo cortical spreading pattern of tau and amyloid in the Alzheimer disease spectrum

(2016) Hanna Cho et al.   ANNALS OF NEUROLOGY

AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies

(2016) Kejal Kantarci et al.   ANNALS OF NEUROLOGY

18F-AV-1451 tau PET imaging correlates strongly with tau neuropathology inMAPTmutation carriers

(2016) Ruben Smith et al.   BRAIN

Regional profiles of the candidate tau PET ligand18F-AV-1451 recapitulate key features of Braak histopathological stages

(2016) Adam J. Schwarz et al.   BRAIN

Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease

(2016) Rik Ossenkoppele et al.   BRAIN

Kinetics of the Tau PET Tracer 18F-AV-1451 (T807) in Subjects with Normal Cognitive Function, Mild Cognitive Impairment, and Alzheimer Disease

(2016) S. Shcherbinin et al.   JOURNAL OF NUCLEAR MEDICINE

Preclinical Characterization of 18F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles

(2016) E. D. Hostetler et al.   JOURNAL OF NUCLEAR MEDICINE

Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study

(2016) Clifford R Jack et al.   LANCET NEUROLOGY

Elevated in vivo [18F]-AV-1451 uptake in a patient with progressive supranuclear palsy

(2016) Jochen Hammes et al.   MOVEMENT DISORDERS

Tau PET in Alzheimer disease and mild cognitive impairment

(2016) Hanna Cho et al.   NEUROLOGY

PET Imaging of Tau Deposition in the Aging Human Brain

(2016) Michael Schöll et al.   NEURON

Dynamic PET Measures of Tau Accumulation in Cognitively Normal Older Adults and Alzheimer’s Disease Patients Measured Using [18F] THK-5351

(2016) Samuel N. Lockhart et al.   PLoS One

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

(2016) Matthew R. Brier et al.   Science Translational Medicine

Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases

(2016) Stephen N. Gomperts et al.   JAMA Neurology

Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: Phase 3 study

(2015) Osama Sabri et al.   Alzheimers & Dementia

Tau positron emission tomographic imaging in aging and early Alzheimer disease

(2015) Keith A. Johnson et al.   ANNALS OF NEUROLOGY

18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease

(2015) R. Harada et al.   JOURNAL OF NUCLEAR MEDICINE

Phase 3 Trial of Flutemetamol Labeled With Radioactive Fluorine 18 Imaging and Neuritic Plaque Density

(2015) Craig Curtis et al.   JAMA Neurology

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

Non-invasive assessment of Alzheimer’s disease neurofibrillary pathology using 18F-THK5105 PET

(2014) Nobuyuki Okamura et al.   BRAIN

Predictive Accuracy of Amyloid Imaging for Progression From Mild Cognitive Impairment to Alzheimer Disease With Different Lengths of Follow-up

(2014) Yan Ma et al.   MEDICINE

Florbetapir F 18 amyloid PET and 36-month cognitive decline:a prospective multicenter study

(2014) P M Doraiswamy et al.   MOLECULAR PSYCHIATRY

Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging

(2013) Keith A. Johnson et al.   Alzheimers & Dementia

[18F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease

(2013) Chun-Fang Xia et al.   Alzheimers & Dementia

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

A 2-process model for neuropathology of Alzheimer's disease

(2013) Dan Mungas et al.   NEUROBIOLOGY OF AGING

Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls

(2013) Masahiro Maruyama et al.   NEURON

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

(2012) Bradley T. Hyman et al.   Alzheimers & Dementia

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study

(2012) Christopher M Clark et al.   LANCET NEUROLOGY

FreeSurfer

(2012) Bruce Fischl   NEUROIMAGE

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

Trans-Synaptic Spread of Tau Pathology In Vivo

(2012) Li Liu et al.   PLoS One

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Neuropathologic features associated with Alzheimer disease diagnosis: Age matters

(2011) L. E. Middleton et al.   NEUROLOGY

Unbiased average age-appropriate atlases for pediatric studies

(2010) Vladimir Fonov et al.   NEUROIMAGE

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

(2008) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY