The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location
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Title
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location
Authors
Keywords
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Journal
NATURE GENETICS
Volume 54, Issue 12, Pages 1881-1894
Publisher
Springer Science and Business Media LLC
Online
2022-12-06
DOI
10.1038/s41588-022-01236-3
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Note: Only part of the references are listed.- Squidpy: a scalable framework for spatial omics analysis
- (2022) Giovanni Palla et al. NATURE METHODS
- Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis
- (2022) David van Bruggen et al. DEVELOPMENTAL CELL
- H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
- (2021) Daniel Haag et al. CANCER CELL
- Heterogeneity of glial progenitor cells during the neurogenesis-to-gliogenesis switch in the developing human cerebral cortex
- (2021) Yuanyuan Fu et al. Cell Reports
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- (2021) Ester Gangoso et al. CELL
- The white matter is a pro-differentiative niche for glioblastoma
- (2021) Lucy J. Brooks et al. Nature Communications
- Perspective of mesenchymal transformation in glioblastoma
- (2021) Yona Kim et al. Acta Neuropathologica Communications
- Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
- (2021) Toshiro Hara et al. CANCER CELL
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- (2021) Alexandro E. Trevino et al. CELL
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- (2021) Gerard L. Brien et al. NATURE GENETICS
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- (2021) Tim Stuart et al. NATURE METHODS
- scCODA is a Bayesian model for compositional single-cell data analysis
- (2021) M. Büttner et al. Nature Communications
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- (2020) Suijuan Zhong et al. NATURE
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- (2020) Kulandaimanuvel Antony Michealraj et al. CELL
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- (2020) Jiarui Ding et al. NATURE BIOTECHNOLOGY
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- (2020) Johannes Gojo et al. CANCER CELL
- Origins and Proliferative States of Human Oligodendrocyte Precursor Cells
- (2020) Wei Huang et al. CELL
- A scalable SCENIC workflow for single-cell gene regulatory network analysis
- (2020) Bram Van de Sande et al. Nature Protocols
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- (2020) Sai Ma et al. CELL
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- (2020) Eugene Drokhlyansky et al. CELL
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- (2020) Daniel Gyllborg et al. NUCLEIC ACIDS RESEARCH
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- (2020) Carol C.L. Chen et al. CELL
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- (2020) Matthias Jürgen Schmitt et al. Cancer Discovery
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- (2019) Azadeh Ebrahimi et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
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- (2019) Mariella Filbin et al. NATURE MEDICINE
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- (2019) Tim Stuart et al. CELL
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- (2019) Volker Hovestadt et al. NATURE
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- (2019) Brian Krug et al. CANCER CELL
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- (2019) Humsa S. Venkatesh et al. NATURE
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- (2019) Varun Venkataramani et al. NATURE
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- (2019) Ziming Du et al. Nature Protocols
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- (2019) Lin Wang et al. Cancer Discovery
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- (2019) Selin Jessa et al. NATURE GENETICS
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- (2019) Xiaoyan Qian et al. NATURE METHODS
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- (2019) Ilya Korsunsky et al. NATURE METHODS
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- (2019) David H. Gutmann et al. NEURON
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- (2019) Surya Nagaraja et al. MOLECULAR CELL
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- (2019) Linda L. Boshans et al. NEUROSCIENCE LETTERS
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- Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain
- (2013) Francesca Viganò et al. NATURE NEUROSCIENCE
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- (2013) P. W. Lewis et al. SCIENCE
- K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
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- Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
- (2012) Dominik Sturm et al. CANCER CELL
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
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- (2012) Gang Wu et al. NATURE GENETICS
- RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
- (2011) Bo Li et al. BMC BIOINFORMATICS
- Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma
- (2011) M. Monje et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
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