Leukemia inhibitory factor, a double-edged sword with therapeutic implications in human diseases
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Title
Leukemia inhibitory factor, a double-edged sword with therapeutic implications in human diseases
Authors
Keywords
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Journal
MOLECULAR THERAPY
Volume 31, Issue 2, Pages 331-343
Publisher
Elsevier BV
Online
2022-12-27
DOI
10.1016/j.ymthe.2022.12.016
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Note: Only part of the references are listed.- Tertiary lymphoid structures in cancer
- (2022) Ton N. Schumacher et al. SCIENCE
- Hallmarks of Cancer: New Dimensions
- (2022) Douglas Hanahan Cancer Discovery
- Leukemia Inhibitory Factor: An Important Cytokine in Pathologies and Cancer
- (2022) Megan M. Jorgensen et al. Biomolecules
- Leukemia inhibitory factor drives glucose metabolic reprogramming to promote breast tumorigenesis
- (2022) Xuetian Yue et al. Cell Death & Disease
- Phase I, first-in-human study of MSC-1 (AZD0171), a humanized anti-leukemia inhibitory factor monoclonal antibody, for advanced solid tumors
- (2022) E. Borazanci et al. ESMO Open
- Leukemia inhibitory factor protects against graft-versus-host disease while preserving graft-versus-leukemia activity
- (2022) Jianming Wang et al. BLOOD
- Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment
- (2022) Yibo Fan et al. GUT
- Leukemia inhibitory factor regulates Schwann cell proliferation and migration and affects peripheral nerve regeneration
- (2021) Qianqian Chen et al. Cell Death & Disease
- MiRNA-29c-3p Promotes Intestinal Inflammation via Targeting Leukemia Inhibitory Factor in Ulcerative Colitis
- (2021) Jian Guo et al. Journal of Inflammation Research
- Plasma proteomics identifies Leukemia Inhibitory Factor (LIF) as a novel predictive biomarker of immune-checkpoint blockade resistance
- (2021) Y. Loriot et al. ANNALS OF ONCOLOGY
- Emerging Perspectives on Leukemia Inhibitory Factor and its Receptor in Cancer
- (2021) Joe Christianson et al. Frontiers in Oncology
- Leukemia Inhibitory Factor Inhibits Plasmacytoid Dendritic Cell Function and Development
- (2020) Renata Sesti-Costa et al. JOURNAL OF IMMUNOLOGY
- Leukemia inhibitory factor regulates the activation of inflammatory signals in macrophages and trophoblast cells
- (2020) Jovane Hamelin-Morrissette et al. MOLECULAR IMMUNOLOGY
- JAK–STAT pathway targeting for the treatment of inflammatory bowel disease
- (2020) Azucena Salas et al. Nature Reviews Gastroenterology & Hepatology
- LIF is essential for ISC function and protects against radiation-induced gastrointestinal syndrome
- (2020) Huaying Wang et al. Cell Death & Disease
- Intestinal Morphogenesis in Development, Regeneration, and Disease: The Potential Utility of Intestinal Organoids for Studying Compartmentalization of the Crypt-Villus Structure
- (2020) Ohman Kwon et al. Frontiers in Cell and Developmental Biology
- The emerging role of leukemia inhibitory factor in cancer and therapy
- (2020) Cen Zhang et al. PHARMACOLOGY & THERAPEUTICS
- Neuroprotective activity of leukemia inhibitory factor is relayed through myeloid zinc finger-1 in a rat model of stroke
- (2019) Stephanie M. Davis et al. METABOLIC BRAIN DISEASE
- STAT4 activation by leukemia inhibitory factor confers a therapeutic effect on intestinal inflammation
- (2019) Yanan S Zhang et al. EMBO JOURNAL
- Leukemia Inhibitory Factor Promotes Castration-resistant Prostate Cancer and Neuroendocrine Differentiation by Activated ZBTB46
- (2019) Yen-Nien Liu et al. CLINICAL CANCER RESEARCH
- Pleiotropy and Specificity: Insights from the Interleukin 6 Family of Cytokines
- (2019) Masaaki Murakami et al. IMMUNITY
- Leukemia inhibitory factor (LIF) modulates the development of dendritic cells in a dual manner
- (2019) Atefeh Yaftiyan et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- EC359-A first-in-class small molecule inhibitor for targeting oncogenic LIFR signaling in triple negative breast cancer
- (2019) Suryavathi Viswanadhapalli et al. MOLECULAR CANCER THERAPEUTICS
- Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring
- (2019) Yu Shi et al. NATURE
- Leukemia inhibitory factor promotes the regeneration of rat uterine horns with full thickness injury
- (2019) Bai Xue et al. WOUND REPAIR AND REGENERATION
- URI is required to maintain intestinal architecture during ionizing radiation
- (2019) Almudena Chaves-Pérez et al. SCIENCE
- Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer
- (2019) Man-Tzu Wang et al. Nature Communications
- LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy
- (2019) Mónica Pascual-García et al. Nature Communications
- MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota
- (2019) Motoko Koyama et al. IMMUNITY
- Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity
- (2019) Vinod Pant et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic Profiling Identifies LIF as a Super-enhancer-Controlled Regulator of Stem Cell–like Properties in Osteosarcoma
- (2019) Bing Lu et al. MOLECULAR CANCER RESEARCH
- Leukemia inhibitory factor produced by fibroblasts within tumor stroma participates in invasion of oral squamous cell carcinoma
- (2018) Yae Ohata et al. PLoS One
- Insight Into Non-Pathogenic Th17 Cells in Autoimmune Diseases
- (2018) Xinyu Wu et al. Frontiers in Immunology
- A phase 1 study of MSC-1, a humanized anti-LIF monoclonal antibody, in patients with advanced solid tumors.
- (2018) David Michael Hyman et al. JOURNAL OF CLINICAL ONCOLOGY
- Leukaemia inhibitory factor is associated with treatment resistance in oesophageal adenocarcinoma
- (2018) Amy M. Buckley et al. Oncotarget
- Leukemia inhibitory factor inhibits the proliferation of gastric cancer by inducing G1-phase arrest
- (2018) Guoxing Xu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Leukemia inhibitory factor functions in parallel with interleukin-6 to promote ovarian cancer growth
- (2018) Karen McLean et al. ONCOGENE
- TLR9 expression and secretion of LIF by prostate cancer cells stimulates accumulation and activity of polymorphonuclear MDSCs
- (2017) Haejung Won et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy
- (2017) Robert Zeiser et al. NEW ENGLAND JOURNAL OF MEDICINE
- Vasculogenesis and angiogenesis initiation under normoxic conditions through Wnt/β-catenin pathway in gliomas
- (2017) Alexandre Vallée et al. REVIEWS IN THE NEUROSCIENCES
- Interleukin-6 Family Cytokines
- (2017) Stefan Rose-John Cold Spring Harbor Perspectives in Biology
- Astrocyte-produced leukemia inhibitory factor expands the neural stem/progenitor pool following perinatal hypoxia-ischemia
- (2016) Ryan J. Felling et al. JOURNAL OF NEUROSCIENCE RESEARCH
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Leukemia inhibitory factor promotes tumor growth and metastasis in human osteosarcoma via activating STAT3
- (2015) Bin Liu et al. APMIS
- Leukemia inhibitory factor tips the immune balance towards regulatory T cells in multiple sclerosis
- (2015) Kris Janssens et al. BRAIN BEHAVIOR AND IMMUNITY
- Leukemia inhibitory factor (LIF)
- (2015) Nicos A. Nicola et al. CYTOKINE & GROWTH FACTOR REVIEWS
- A Key Role for Leukemia Inhibitory Factor in C26 Cancer Cachexia
- (2015) Danielle N. Seto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer cachexia, mechanism and treatment
- (2015) Tomoyoshi Aoyagi et al. World Journal of Gastrointestinal Oncology
- LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway
- (2015) Xiaoyan Li et al. Oncotarget
- Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation
- (2015) Samadhi Aparicio-Siegmund et al. Oncotarget
- Leukemia inhibitory factor protects the lung during respiratory syncytial viral infection
- (2014) Robert F Foronjy et al. BMC IMMUNOLOGY
- Tumor-Associated Macrophages: From Mechanisms to Therapy
- (2014) Roy Noy et al. IMMUNITY
- Upregulation of Leukemia Inhibitory Factor (LIF) during the Early Stage of Optic Nerve Regeneration in Zebrafish
- (2014) Kazuhiro Ogai et al. PLoS One
- The Neuron Regrowth Is Associated with the Proliferation of Neural Precursor Cells after Leukemia Inhibitory Factor Administration following Spinal Cord Injury in Mice
- (2014) Yubo Li et al. PLoS One
- LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers
- (2014) Haiyang Yu et al. Nature Communications
- LIF Mediates Proinvasive Activation of Stromal Fibroblasts in Cancer
- (2014) Jean Albrengues et al. Cell Reports
- Recombinant leukemia inhibitory factor suppresses human medullary thyroid carcinoma cell line xenografts in mice
- (2013) Dmytro Starenki et al. CANCER LETTERS
- Impact of LIF (leukemia inhibitory factor) expression in malignant melanoma
- (2013) Silke Kuphal et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance
- (2013) Shu-Chen Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- Leukemia Inhibitory Factor Is Essential for Subventricular Zone Neural Stem Cell and Progenitor Homeostasis as Revealed by a Novel Flow Cytometric Analysis
- (2012) Krista D. Buono et al. DEVELOPMENTAL NEUROSCIENCE
- An anti-inflammatory role for leukemia inhibitory factor receptor signaling in regenerating skeletal muscle
- (2012) Liam C. Hunt et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Leukemia Inhibitory Factor Signaling Is Required for Lung Protection during Pneumonia
- (2012) L. J. Quinton et al. JOURNAL OF IMMUNOLOGY
- LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker
- (2012) Dahu Chen et al. NATURE MEDICINE
- Strategies for Homeostatic Stem Cell Self-Renewal in Adult Tissues
- (2011) Benjamin D. Simons et al. CELL
- Treg versus Th17 lymphocyte lineages are cross-regulated by LIF versus IL-6
- (2011) Wenda Gao et al. CELL CYCLE
- Leukemia Inhibitory Factor Inhibits T Helper 17 Cell Differentiation and Confers Treatment Effects of Neural Progenitor Cell Therapy in Autoimmune Disease
- (2011) Wei Cao et al. IMMUNITY
- Effect of leukemia inhibitory factor on corneal nerve regeneration of rabbit eyes after laser in situ keratomileusis
- (2011) Shuling Pan et al. NEUROSCIENCE LETTERS
- Gprc5a Deletion Enhances the Transformed Phenotype in Normal and Malignant Lung Epithelial Cells by Eliciting Persistent Stat3 Signaling Induced by Autocrine Leukemia Inhibitory Factor
- (2010) Y. Chen et al. CANCER RESEARCH
- Overview of the immune response
- (2010) David D. Chaplin JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury
- (2010) Masahiko Abematsu et al. JOURNAL OF CLINICAL INVESTIGATION
- TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma
- (2009) Silvia Peñuelas et al. CANCER CELL
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Recombinant human leukemia inhibitory factor does not improve implantation and pregnancy outcomes after assisted reproductive techniques in women with recurrent unexplained implantation failure
- (2008) Peter R. Brinsden et al. FERTILITY AND STERILITY
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