LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

(2018) Sanjeev Mariathasan et al.   NATURE

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

(2017) Pornpimol Charoentong et al.   Cell Reports

ZEB1 regulates glioma stemness through LIF repression

(2017) Lincoln A. Edwards et al.   Scientific Reports

CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells

(2016) Alan L. Chang et al.   CANCER RESEARCH

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies

(2016) Robert L. Bowman et al.   Cell Reports

Leukemia inhibitory factor tips the immune balance towards regulatory T cells in multiple sclerosis

(2015) Kris Janssens et al.   BRAIN BEHAVIOR AND IMMUNITY

Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy

(2015) Dongjun Peng et al.   NATURE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

T cell exclusion, immune privilege, and the tumor microenvironment

(2015) J. A. Joyce et al.   SCIENCE

Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy

(2015) Mihaela Angelova et al.   GENOME BIOLOGY

Most Human Non-GCIMP Glioblastoma Subtypes Evolve from a Common Proneural-like Precursor Glioma

(2014) Tatsuya Ozawa et al.   CANCER CELL

PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors

(2014) Alena Gros et al.   JOURNAL OF CLINICAL INVESTIGATION

LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers

(2014) Haiyang Yu et al.   Nature Communications

LIF Mediates Proinvasive Activation of Stromal Fibroblasts in Cancer

(2014) Jean Albrengues et al.   Cell Reports

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance

(2013) Shu-Chen Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Organotypic slice cultures of human glioblastoma reveal different susceptibilities to treatments

(2013) Felicitas Merz et al.   NEURO-ONCOLOGY

Jak/Stat3 Signaling Promotes Somatic Cell Reprogramming by Epigenetic Regulation

(2012) Yong Tang et al.   STEM CELLS

Chronic Virus Infection Enforces Demethylation of the Locus that Encodes PD-1 in Antigen-Specific CD8+ T Cells

(2011) Ben Youngblood et al.   IMMUNITY

LIF-Dependent Signaling: New Pieces in the Lego

(2011) Marie-Emmanuelle Mathieu et al.   Stem Cell Reviews and Reports

Optimization of lentiviral vector transduction into peripheral blood mononuclear cells in combination with the fibronectin fragment CH-296 stimulation

(2010) H. Chono et al.   JOURNAL OF BIOCHEMISTRY

TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma

(2009) Silvia Peñuelas et al.   CANCER CELL

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

Expression of leukaemia inhibitory factor in epithelial ovarian carcinoma: correlation with clinical characteristics

(2008) F Ye et al.   HISTOPATHOLOGY