Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes

Primary cilia in the postnatal brain: Subcellular compartments for organizing neuromodulatory signaling

(2022) Lauren Tereshko et al.   CURRENT OPINION IN NEUROBIOLOGY

A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility

(2022) Shu-Hsien Sheu et al.   CELL

Reactive astrocyte nomenclature, definitions, and future directions

(2021) Carole Escartin et al.   NATURE NEUROSCIENCE

Molecular diversity of diencephalic astrocytes reveals adult astrogenesis regulated by Smad4

(2021) Stefanie Ohlig et al.   EMBO JOURNAL

Primary Cilia in Glial Cells: An Oasis in the Journey to Overcoming Neurodegenerative Diseases

(2021) Soo Mi Ki et al.   Frontiers in Neuroscience

Interplay of RFX transcription factors 1, 2 and 3 in motile ciliogenesis

(2020) Sylvain Lemeille et al.   NUCLEIC ACIDS RESEARCH

Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model

(2020) Kevin A. Guttenplan et al.   Nature Communications

Mitochondrial spongiotic brain disease: astrocytic stress and harmful rapamycin and ketosis effect

(2020) Olesia Ignatenko et al.   Life Science Alliance

Whole-genome screen identifies diverse pathways that negatively regulate ciliogenesis

(2020) Marion Failler et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure

(2019) Yan Wang et al.   CNS Neuroscience & Therapeutics

Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity

(2019) Maria S. Ioannou et al.   CELL

Astrocyte‐specific deletion of the mitochondrial m ‐AAA protease reveals glial contribution to neurodegeneration

(2019) Sara Murru et al.   GLIA

Astrocyte‐to‐astrocyte contact and a positive feedback loop of growth factor signaling regulate astrocyte maturation

(2019) Jiwen Li et al.   GLIA

Three-dimensional architecture of epithelial primary cilia

(2019) Shufeng Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis

(2019) Martin D. Burkhalter et al.   JOURNAL OF CLINICAL INVESTIGATION

CiliaCarta: An integrated and validated compendium of ciliary genes

(2019) Teunis J. P. van Dam et al.   PLoS One

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions

(2019) Saara Forsström et al.   Cell Metabolism

Dynamic Changes in Ultrastructure of the Primary Cilium in Migrating Neuroblasts in the Postnatal Brain

(2019) Mami Matsumoto et al.   JOURNAL OF NEUROSCIENCE

Combining Precursor and Fragment Information for Improved Detection of Differential Abundance in Data Independent Acquisition

(2019) Ting Huang et al.   MOLECULAR & CELLULAR PROTEOMICS

Primary cilia mediate mitochondrial stress responses to promote dopamine neuron survival in a Parkinson’s disease model

(2019) Ji-Eun Bae et al.   Cell Death & Disease

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

(2018) Seung Pil Yun et al.   NATURE MEDICINE

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update

(2018) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy

(2018) Olesia Ignatenko et al.   Nature Communications

The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain

(2018) Matthew M. Boisvert et al.   Cell Reports

Neuronal and astrocytic primary cilia in the mature brain

(2018) Ashley Sterpka et al.   PHARMACOLOGICAL RESEARCH

An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody

(2017) Mykhailo Y. Batiuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Differential analysis of RNA-seq incorporating quantification uncertainty

(2017) Harold Pimentel et al.   NATURE METHODS

Intraflagellar Transport and Ciliary Dynamics

(2017) Hiroaki Ishikawa et al.   Cold Spring Harbor Perspectives in Biology

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

(2017) Inge Kühl et al.   eLife

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism

(2016) Joni Nikkanen et al.   Cell Metabolism

TAp73 is a central transcriptional regulator of airway multiciliogenesis

(2016) Alice Nemajerova et al.   GENES & DEVELOPMENT

Unifying the p73 knockout phenotypes: TAp73 orchestrates multiciliogenesis

(2016) Marco Napoli et al.   GENES & DEVELOPMENT

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Mitochondrial diseases

(2016) Gráinne S. Gorman et al.   Nature Reviews Disease Primers

Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

(2015) Lucy Liu et al.   CELL

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

(2012) Jian Ye et al.   BMC BIOINFORMATICS

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Inferring direct DNA binding from ChIP-seq

(2012) Timothy L. Bailey et al.   NUCLEIC ACIDS RESEARCH

Stages of ciliogenesis and regulation of ciliary length

(2011) Prachee Avasthi et al.   DIFFERENTIATION

Mitochondrial recessive ataxia syndrome mimicking dominant spinocerebellar ataxia

(2011) Eino J.H. Palin et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins

(2011) Christine E. Larkins et al.   MOLECULAR BIOLOGY OF THE CELL

Transcriptional control of genes involved in ciliogenesis: a first step in making cilia

(2010) Joëlle Thomas et al.   BIOLOGY OF THE CELL

The Subventricular Zone En-face: Wholemount Staining and Ependymal Flow

(2010) Zaman Mirzadeh et al.   Jove-Journal of Visualized Experiments

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain

(2009) B. V. Jacquet et al.   DEVELOPMENT

Building it up and taking it down: The regulation of vertebrate ciliogenesis

(2008) Nicole Santos et al.   DEVELOPMENTAL DYNAMICS

Foxj1 transcription factors are master regulators of the motile ciliogenic program

(2008) Xianwen Yu et al.   NATURE GENETICS

The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryos

(2008) Jennifer L Stubbs et al.   NATURE GENETICS

The astrocyte odyssey

(2008) D WANG et al.   PROGRESS IN NEUROBIOLOGY