Archeal tRNA meets biotechnology: From vaccines to genetic code expansion

Ancestral archaea expanded the genetic code with pyrrolysine

(2022) Li-Tao Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic Encoding of Three Distinct Noncanonical Amino Acids Using Reprogrammed Initiator and Nonsense Codons

(2021) Jeffery M. Tharp et al.   ACS Chemical Biology

Using Genetic Code Expansion for Protein Biochemical Studies

(2020) Christina Z. Chung et al.   Frontiers in Bioengineering and Biotechnology

Methanomethylophilus alvus Mx1201 provides basis for mutual orthogonal pyrrolysyl tRNA/aminoacyl-tRNA synthetase pairs in mammalian cells.

(2018) Birthe Meineke et al.   ACS Chemical Biology

Saturation of recognition elements blocks evolution of new tRNA identities

(2016) A. Saint-Leger et al.   Science Advances

Unique Characteristics of the Pyrrolysine System in the 7th Order of Methanogens: Implications for the Evolution of a Genetic Code Expansion Cassette

(2014) Guillaume Borrel et al.   ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL

Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs

(2012) J. P. Wurm et al.   RNA