H2S- and Redox-State-Mediated PTP1B S-Sulfhydration in Insulin Signaling

Metformin and Insulin Resistance: A Review of the Underlying Mechanisms behind Changes in GLUT4-Mediated Glucose Transport

(2022) Rok Herman et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cystathionine γ lyase S-sulfhydrates Drp1 to ameliorate heart dysfunction

(2022) Dan Wu et al.   Redox Biology

Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy

(2021) Iram Khan Iqbal et al.   Autophagy

Insufficient S-sulfhydration of Methylenetetrahydrofolate Reductase Contribute to the Progress of Hyperhomocysteinemia

(2021) Dengyu Ji et al.   ANTIOXIDANTS & REDOX SIGNALING

Anticancer mechanisms of metformin: A review of the current evidence

(2020) Bin Zhao et al.   LIFE SCIENCES

Role of Mitochondria in the Mechanism(s) of Action of Metformin

(2019) Guillaume Vial et al.   Frontiers in Endocrinology

Administration of metformin alleviates atherosclerosis by promoting H2S production via regulating CSE expression

(2019) Xiaofeng Ma et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hydrogen Sulfide and Glucose Homeostasis: A Tale of Sweet and the Stink

(2018) Ashley Untereiner et al.   ANTIOXIDANTS & REDOX SIGNALING

Quantitative and comparative liquid chromatography-electrospray ionization-mass spectrometry analyses of hydrogen sulfide and thiol metabolites derivaitized with 2-iodoacetanilide isotopologues

(2018) Der-Yen Lee et al.   JOURNAL OF CHROMATOGRAPHY A

Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development

(2018) Navasona Krishnan et al.   Nature Communications

Quantitative display of the redox status of proteins with maleimide-polyethylene glycol tagging

(2018) Yu-Jung Lee et al.   ELECTROPHORESIS

Cystathionine γ-lyase deficiency aggravates obesity-related insulin resistance via FoxO1-dependent hepatic gluconeogenesis

(2018) Wei Guo et al.   FASEB JOURNAL

A potent, selective, and orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models

(2017) Navasona Krishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages

(2015) Beth Kelly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

H 2 S: A Novel Gasotransmitter that Signals by Sulfhydration

(2015) Bindu D. Paul et al.   TRENDS IN BIOCHEMICAL SCIENCES

Cytokine-Induced GAPDH Sulfhydration Affects PSD95 Degradation and Memory

(2014) Sajad Mir et al.   MOLECULAR CELL

Metformin raises hydrogen sulfide tissue concentrations in various mouse organs

(2014) Bogdan Wiliński et al.   Pharmacological Reports

Hydrogen Sulfide Treatment Promotes Glucose Uptake by Increasing Insulin Receptor Sensitivity and Ameliorates Kidney Lesions in Type 2 Diabetes

(2013) Rong Xue et al.   ANTIOXIDANTS & REDOX SIGNALING

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-  receptor tyrosine kinase signaling

(2013) M. Dagnell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen Sulfide Impairs Glucose Utilization and Increases Gluconeogenesis in Hepatocytes

(2012) Ling Zhang et al.   ENDOCRINOLOGY

Hydrogen Sulfide-Linked Sulfhydration of NF-κB Mediates Its Antiapoptotic Actions

(2012) Nilkantha Sen et al.   MOLECULAR CELL

H2S signalling through protein sulfhydration and beyond

(2012) Bindu D. Paul et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

From Sulfenylation to Sulfhydration: What a Thiolate Needs to Tolerate

(2012) T. Finkel   Science Signaling

Hydrogen Sulfide and Cell Signaling

(2011) Ling Li et al.   Annual Review of Pharmacology and Toxicology

PLP-dependent H2S biogenesis

(2011) Sangita Singh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Conformation-Sensing Antibodies Stabilize the Oxidized Form of PTP1B and Inhibit Its Phosphatase Activity

(2011) Aftabul Haque et al.   CELL

Analysis and Functional Prediction of Reactive Cysteine Residues

(2011) Stefano M. Marino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

H2S-Induced Sulfhydration of the Phosphatase PTP1B and Its Role in the Endoplasmic Reticulum Stress Response

(2011) N. Krishnan et al.   Science Signaling

Cysteine-Based Redox Switches in Enzymes

(2010) Chananat Klomsiri et al.   ANTIOXIDANTS & REDOX SIGNALING

H2S Biogenesis by Human Cystathionine γ-Lyase Leads to the Novel Sulfur Metabolites Lanthionine and Homolanthionine and Is Responsive to the Grade of Hyperhomocysteinemia

(2009) Taurai Chiku et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions

(2009) Sangita Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling

Discovering mechanisms of signaling-mediated cysteine oxidation

(2008) Leslie B Poole et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Prodrugs of Phosphates and Phosphonates

(2008) Scott J. Hecker et al.   JOURNAL OF MEDICINAL CHEMISTRY