The Flavonoid Naringenin Alleviates Collagen-Induced Arthritis through Curbing the Migration and Polarization of CD4+ T Lymphocyte Driven by Regulating Mitochondrial Fission

Naringenin as a natural immunomodulator against T cell-mediated autoimmune diseases: literature review and network-based pharmacology study

(2022) Zejin Liu et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Mitochondrial fission mediated by Drp1-Fis1 pathway and neurodegenerative diseases

(2022) Wenjia Shi et al.   REVIEWS IN THE NEUROSCIENCES

Berberine Delays Onset of Collagen-Induced Arthritis through T Cell Suppression

(2021) Alexandra A. Vita et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Distinct fission signatures predict mitochondrial degradation or biogenesis

(2021) Tatjana Kleele et al.   NATURE

Mitochondrial Fission Protein 1: Emerging Roles in Organellar Form and Function in Health and Disease

(2021) Ugochukwu Kelvin Ihenacho et al.   Frontiers in Endocrinology

Mitochondrial fusion and fission: The fine‐tune balance for cellular homeostasis

(2021) Mary Adebayo et al.   FASEB JOURNAL

Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development

(2021) Jianli He et al.   Nature Communications

Naringenin nanocrystals for improving anti-rheumatoid arthritis activity

(2021) Guangshuai Zhang et al.   Asian Journal of Pharmaceutical Sciences

Targeting bioenergetics prevents CD4 T cell–mediated activation of synovial fibroblasts in rheumatoid arthritis

(2020) Andreea Petrasca et al.   RHEUMATOLOGY

Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexate Treated, Show More DNA Methylation Differences in CD4+ Memory Than in CD4+ Naïve T Cells

(2020) Kari Guderud et al.   Frontiers in Immunology

Regulation of Mammalian Mitochondrial Dynamics: Opportunities and Challenges

(2020) Rong Yu et al.   Frontiers in Endocrinology

The purinergic receptor P2Y11 choreographs the polarization, mitochondrial metabolism, and migration of T lymphocytes

(2020) Carola Ledderose et al.   Science Signaling

Naringenin attenuates experimental autoimmune encephalomyelitis by protecting the intact of blood-brain barrier and controlling inflammatory cell migration

(2020) Xinli Niu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Impact of Janus kinase inhibitors on risk of cardiovascular events in patients with rheumatoid arthritis: systematic review and meta-analysis of randomised controlled trials

(2019) Wenhui Xie et al.   ANNALS OF THE RHEUMATIC DISEASES

Regulators of T‐cell fate: Integration of cell migration, differentiation and function

(2019) Joanna R. Groom   IMMUNOLOGICAL REVIEWS

The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels

(2019) Yuan Zhou et al.   ACS Chemical Neuroscience

Mdivi-1 alleviates blood-brain barrier disruption and cell death in experimental traumatic brain injury by mitigating autophagy dysfunction and mitophagy activation

(2018) Qiong Wu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Purinergic P2X4 receptors and mitochondrial ATP production regulate T cell migration

(2018) Carola Ledderose et al.   JOURNAL OF CLINICAL INVESTIGATION

Naringenin as a potential immunomodulator in therapeutics

(2018) Wenfeng Zeng et al.   PHARMACOLOGICAL RESEARCH

Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming

(2018) Luca Simula et al.   Cell Reports

Naringenin Ameliorates Acute Inflammation by Regulating Intracellular Cytokine Degradation

(2017) Lingtao Jin et al.   JOURNAL OF IMMUNOLOGY

Pathogenetic insights from the treatment of rheumatoid arthritis

(2017) Iain B McInnes et al.   LANCET

The mitochondrial dynamics in cancer and immune-surveillance

(2017) Luca Simula et al.   SEMINARS IN CANCER BIOLOGY

Expansions of Cytotoxic CD4+CD28− T Cells Drive Excess Cardiovascular Mortality in Rheumatoid Arthritis and Other Chronic Inflammatory Conditions and Are Triggered by CMV Infection

(2017) Iain Broadley et al.   Frontiers in Immunology

Clathrin regulates lymphocyte migration by driving actin accumulation at the cellular leading edge

(2016) Guillermo Ramírez-Santiago et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Rheumatoid arthritis

(2016) Josef S Smolen et al.   LANCET

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

(2016) E. Q. Toyama et al.   SCIENCE

Computational properties of mitochondria in T cell activation and fate

(2016) Roman Uzhachenko et al.   Open Biology

Naringenin Ameliorated Kidney Injury through Let-7a/TGFBR1 Signaling in Diabetic Nephropathy

(2016) Ning Yan et al.   Journal of Diabetes Research

Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis

(2015) G Reynolds et al.   ANNALS OF THE RHEUMATIC DISEASES

Serious infection during etanercept, infliximab and adalimumab therapy for rheumatoid arthritis: A literature review

(2015) Colum Downey   International Journal of Rheumatic Diseases

Naringenin inhibits dendritic cell maturation and has therapeutic effects in a murine model of collagen-induced arthritis

(2015) Yi-Rong Li et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study

(2014) Marita Cross et al.   ANNALS OF THE RHEUMATIC DISEASES

Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration

(2014) Liang Ma et al.   CELL RESEARCH

The Role of PKD in Cell Polarity, Biosynthetic Pathways, and Organelle/F-actin Distribution

(2014) Nur Atik et al.   CELL STRUCTURE AND FUNCTION

A Simplified Up-Down Method (SUDO) for Measuring Mechanical Nociception in Rodents Using von Frey Filaments

(2014) Robert P Bonin et al.   Molecular Pain

Protective effect of naringenin against experimental colitis via suppression of Toll-like receptor 4/NF-κB signalling

(2013) Wei Dou et al.   BRITISH JOURNAL OF NUTRITION

Flavonoids as prospective compounds for anti-cancer therapy

(2013) Divyashree Ravishankar et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The many faces of CD4 T cells: Roles in immunity and disease

(2013) Federica Sallusto et al.   SEMINARS IN IMMUNOLOGY

Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease

(2012) P L Klarenbeek et al.   ANNALS OF THE RHEUMATIC DISEASES

Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4+ T Cells

(2010) J. J. O'Shea et al.   SCIENCE

Multiparameter Phospho-Flow Analysis of Lymphocytes in Early Rheumatoid Arthritis: Implications for Diagnosis and Monitoring Drug Therapy

(2009) Carole L. Galligan et al.   PLoS One

Altered T-cell subtypes in spondyloarthritis, rheumatoid arthritis and polymyalgia rheumatica

(2009) Christian Dejaco et al.   RHEUMATOLOGY INTERNATIONAL