β-Caryophyllene Acts as a Ferroptosis Inhibitor to Ameliorate Experimental Colitis

The multifaceted role of ferroptosis in liver disease

(2022) Junyi Chen et al.   CELL DEATH AND DIFFERENTIATION

Non‐psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors‐, endocannabinoids‐, and NF‐κB ‐mediated signaling

(2022) Vittoria Borgonetti et al.   PHYTOTHERAPY RESEARCH

STAT3-mediated ferroptosis is involved in ulcerative colitis

(2022) Fangfang Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Furin inhibits epithelial cell injury and alleviates experimental colitis by activating the Nrf2-Gpx4 signaling pathway

(2021) Shouquan Dong et al.   DIGESTIVE AND LIVER DISEASE

Ferroptosis in infection, inflammation, and immunity

(2021) Xin Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

β-Caryophyllene, A Natural Dietary CB2 Receptor Selective Cannabinoid can be a Candidate to Target the Trinity of Infection, Immunity, and Inflammation in COVID-19

(2021) Niraj Kumar Jha et al.   Frontiers in Pharmacology

A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid

(2021) Hebaallah Mamdouh Hashiesh et al.   BIOMEDICINE & PHARMACOTHERAPY

A functional motif of long noncoding RNA Nron against osteoporosis

(2021) Fujun Jin et al.   Nature Communications

The Essential Oil of Artemisia argyi H.Lév. and Vaniot Attenuates NLRP3 Inflammasome Activation in THP-1 Cells

(2021) Pengxiao Chen et al.   Frontiers in Pharmacology

Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases

(2021) Yi Yu et al.   Cell Death Discovery

Molecular docking, DFT analysis, and dynamics simulation of natural bioactive compounds targeting ACE2 and TMPRSS2 dual binding sites of spike protein of SARS CoV-2

(2021) Rohitash Yadav et al.   JOURNAL OF MOLECULAR LIQUIDS

Emerging Pathological Engagement of Ferroptosis in Gut Diseases

(2021) Weihua Gao et al.   Oxidative Medicine and Cellular Longevity

The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression

(2020) Guang Lei et al.   CELL RESEARCH

The epigenetic regulators and metabolic changes in ferroptosis-associated cancer progression

(2020) Yuqing Wu et al.   Molecular Cancer

Ferroptosis involves in intestinal epithelial cell death in ulcerative colitis

(2020) Minyi Xu et al.   Cell Death & Disease

Targeting ferroptosis alleviates methionine‐choline deficient (MCD)‐diet induced NASH by suppressing liver lipotoxicity

(2020) Xiaoya Li et al.   LIVER INTERNATIONAL

The emerging role of ferroptosis in inflammation

(2020) Yitian Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Berberine-Loaded Nanostructured Lipid Carriers Enhance the Treatment of Ulcerative Colitis

(2020) Jianping Deng et al.   International Journal of Nanomedicine

Quercetin alleviates acute kidney injury by inhibiting ferroptosis

(2020) Yue Wang et al.   Journal of Advanced Research

Ferroptosis mediated DSS-induced ulcerative colitis associated with Nrf2/HO-1 signaling pathway

(2020) Yeru Chen et al.   IMMUNOLOGY LETTERS

Curculigoside inhibits ferroptosis in ulcerative colitis through the induction of GPX4

(2020) Shujun Wang et al.   LIFE SCIENCES

Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation

(2020) Rosaria Scandiffio et al.   Nutrients

Ulcerative colitis

(2020) Taku Kobayashi et al.   Nature Reviews Disease Primers

Ferroptosis: molecular mechanisms and health implications

(2020) Daolin Tang et al.   CELL RESEARCH

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

(2019) Weimin Wang et al.   NATURE

Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD

(2019) Yi Rang Na et al.   Nature Reviews Gastroenterology & Hepatology

β-Caryophyllene Mitigates Collagen Antibody Induced Arthritis (CAIA) in Mice Through a Cross-Talk between CB2 and PPAR-γ Receptors

(2019) Natasha Irrera et al.   Biomolecules

Combination of Imipramine, a sphingomyelinase inhibitor, and β-caryophyllene improve their therapeutic effects on experimental autoimmune encephalomyelitis (EAE)

(2019) Vahid Reza Askari et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

β-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain

(2019) Esraa Aly et al.   MOLECULES

Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota

(2018) Ce Tang et al.   NATURE IMMUNOLOGY

Reduced expression of the ferroptosis inhibitor glutathione peroxidase-4 in multiple sclerosis and experimental autoimmune encephalomyelitis

(2018) Che-Lin Hu et al.   JOURNAL OF NEUROCHEMISTRY

In vitro and in vivo anti-inflammatory effects of theaflavin-3,3′-digallate on lipopolysaccharide-induced inflammation

(2017) Yanting Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies

(2017) Siew C Ng et al.   LANCET

The effect of β-caryophyllene on nonalcoholic steatohepatitis

(2017) Naoya Arizuka et al.   Journal of Toxicologic Pathology

Efficient Early Drug Development for Ulcerative Colitis

(2016) Reena Khanna et al.   GASTROENTEROLOGY

The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Tailoring anti-TNF therapy in IBD: drug levels and disease activity

(2014) Shomron Ben-Horin et al.   Nature Reviews Gastroenterology & Hepatology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Ulcerative colitis

(2012) Ingrid Ordás et al.   LANCET

β-Caryophyllene Inhibits Dextran Sulfate Sodium-Induced Colitis in Mice through CB2 Receptor Activation and PPARγ Pathway

(2011) Allisson Freire Bento et al.   AMERICAN JOURNAL OF PATHOLOGY

Direct Health Care Costs of Crohn's Disease and Ulcerative Colitis in US Children and Adults

(2008) Michael D. Kappelman et al.   GASTROENTEROLOGY