Cerebral Folate Metabolism in Post-Mortem Alzheimer’s Disease Tissues: A Small Cohort Study

Folate Related Pathway Gene Analysis Reveals a Novel Metabolic Variant Associated with Alzheimer’s Disease with a Change in Metabolic Profile

(2022) Jaleel Miyan et al.   Metabolites

Rab6A as a Pan-Astrocytic Marker in Mouse and Human Brain, and Comparison with Other Glial Markers (GFAP, GS, Aldh1L1, SOX9)

(2021) Linda Melzer et al.   Cells

Therapy for Alzheimer’s disease: Missing Targets and Functional Markers?

(2021) Milan Stoiljkovic et al.   AGEING RESEARCH REVIEWS

Glymphatic System Impairment in Alzheimer’s Disease and Idiopathic Normal Pressure Hydrocephalus

(2020) Benjamin C. Reeves et al.   TRENDS IN MOLECULAR MEDICINE

Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model

(2020) Ian F Harrison et al.   BRAIN

CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression

(2020) Xuanye Cao et al.   JOURNAL OF MEDICAL GENETICS

Correction: Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study

(2020) Uma V. Mahajan et al.   PLOS MEDICINE

Astrocytes, HIV and the Glymphatic System: A Disease of Disrupted Waste Management?

(2020) Caitlin Tice et al.   Frontiers in Cellular and Infection Microbiology

The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices

(2020) Oliver Cameron Reddy et al.   Brain Sciences

Vaccination against β-Amyloid as a Strategy for the Prevention of Alzheimer’s Disease

(2020) Francesca Mantile et al.   Biology-Basel

Loss of ALDH1L1 folate enzyme confers a selective metabolic advantage for tumor progression

(2019) Sergey A. Krupenko et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Upregulation of reduced folate carrier by vitamin D enhances brain folate uptake in mice lacking folate receptor alpha

(2019) Camille Alam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subarachnoid cerebrospinal fluid is essential for normal development of the cerebral cortex

(2019) Jaleel Miyan et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Role of Single-Nucleotide Polymorphisms in the Function of Candidate Tumor Suppressor ALDH1L1

(2019) Sergey A. Krupenko et al.   Frontiers in Genetics

Altered folate binding protein expression and folate delivery are associated with congenital hydrocephalus in the hydrocephalic Texas rat

(2018) Alicia Requena Jimenez et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Genetic assessment and folate receptor autoantibodies in infantile-onset cerebral folate deficiency (CFD) syndrome

(2018) V.Th. Ramaekers et al.   MOLECULAR GENETICS AND METABOLISM

Cerebrospinal fluid and the early brain development of autism

(2018) Mark D. Shen   Journal of Neurodevelopmental Disorders

The glymphatic pathway in neurological disorders

(2018) Martin Kaag Rasmussen et al.   LANCET NEUROLOGY

Folinic acid therapy in cerebral folate deficiency: marked improvement in an adult patient

(2017) Ivan Karin et al.   JOURNAL OF NEUROLOGY

Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease

(2017) Elijah Mak et al.   NEUROBIOLOGY OF AGING

Brain Ventricular Volume and Cerebrospinal Fluid Biomarkers of Alzheimer's Disease

(2017) Brian R. Ott et al.   JOURNAL OF ALZHEIMERS DISEASE

Extended post-mortem delay times should not be viewed as a deterrent to the scientific investigation of human brain tissue: a study from the Brains for Dementia Research Network Neuropathology Study Group, UK

(2016) Andrew C. Robinson et al.   ACTA NEUROPATHOLOGICA

Surgery is associated with ventricular enlargement as well as cognitive and functional decline

(2016) Katie J. Schenning et al.   Alzheimers & Dementia

Posterior Ventricular Enlargement to Differentiate Dementia with Lewy Bodies from Alzheimer’s Disease

(2016) Byoung Seok Ye et al.   JOURNAL OF ALZHEIMERS DISEASE

Neonatal hydrocephalus is a result of a block in folate handling and metabolism involving 10-formyltetrahydrofolate dehydrogenase

(2016) Naila Naz et al.   JOURNAL OF NEUROCHEMISTRY

Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial

(2016) R E Frye et al.   MOLECULAR PSYCHIATRY

Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease

(2016) Weiguo Peng et al.   NEUROBIOLOGY OF DISEASE

Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups

(2016) Richard E. Frye et al.   Frontiers in Neuroscience

Early life adversity induced third ventricular enlargement in young adult male patients suffered from major depressive disorder: A study of brain morphology

(2015) Hongyi Zhao et al.   FOLIA MORPHOLOGICA

Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury

(2014) Jeffrey J. Iliff et al.   JOURNAL OF NEUROSCIENCE

Folinic acid treatment for schizophrenia associated with folate receptor autoantibodies

(2014) V.T. Ramaekers et al.   MOLECULAR GENETICS AND METABOLISM

Clinical recognition and aspects of the cerebral folate deficiency syndromes

(2013) Vincent Ramaekers et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Autism Spectrum Disorder Is Associated with Ventricular Enlargement in a Low Birth Weight Population

(2013) Tammy Z. Movsas et al.   JOURNAL OF PEDIATRICS

Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma

(2013) Marcel Grapp et al.   Nature Communications

Third ventricular enlargement in early stages of multiple sclerosis is a predictor of motor and neuropsychological deficits: a cross-sectional study

(2013) Martin Müller et al.   BMJ Open

Adult-Onset Cerebral Folate Deficiency

(2012) Zsila Sadighi et al.   ARCHIVES OF NEUROLOGY

Cerebral folate receptor autoantibodies in autism spectrum disorder

(2012) R E Frye et al.   MOLECULAR PSYCHIATRY

Role of folate receptor autoantibodies in infantile autism

(2012) V T Ramaekers et al.   MOLECULAR PSYCHIATRY

Hippocampal Atrophy and Ventricular Enlargement in Normal Aging, Mild Cognitive Impairment (MCI), and Alzheimer Disease

(2011) Liana G. Apostolova et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Ventricular enlargement in new-onset pediatric epilepsies

(2011) Daren C. Jackson et al.   EPILEPSIA

Correlations between ventricular enlargement and gray and white matter volumes of cortex, thalamus, striatum, and internal capsule in schizophrenia

(2011) Guillermo Horga et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Study factors influencing ventricular enlargement in schizophrenia: A 20year follow-up meta-analysis

(2011) Angelo Sayo et al.   NEUROIMAGE

Kearns-Sayre syndrome: Cerebral folate deficiency, MRI findings and new cerebrospinal fluid biochemical features

(2010) Mercedes Serrano et al.   MITOCHONDRION

Ventricular enlargement and mild cognitive impairment in early Parkinson's disease

(2010) Turi O. Dalaker et al.   MOVEMENT DISORDERS

ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A

(2010) N V Oleinik et al.   ONCOGENE

Progressive lateral ventricular enlargement in schizophrenia: A meta-analysis of longitudinal MRI studies

(2010) Matthew J. Kempton et al.   SCHIZOPHRENIA RESEARCH

Folate Receptor Alpha Defect Causes Cerebral Folate Transport Deficiency: A Treatable Neurodegenerative Disorder Associated with Disturbed Myelin Metabolism

(2009) Robert Steinfeld et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Addressing a Folate Imbalance in Fetal Cerebrospinal Fluid Can Decrease the Incidence of Congenital Hydrocephalus

(2009) Sarah Cains et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cerebral folate deficiency and CNS inflammatory markers in Alpers disease

(2009) Oswald Hasselmann et al.   MOLECULAR GENETICS AND METABOLISM

Mapping correlations between ventricular expansion and CSF amyloid and tau biomarkers in 240 subjects with Alzheimer's disease, mild cognitive impairment and elderly controls

(2009) Yi-Yu Chou et al.   NEUROIMAGE

Rate of ventricular enlargement in multiple sclerosis: a nine-year magnetic resonance imaging follow-up study

(2008) J. Martola et al.   ACTA RADIOLOGICA

Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database

(2008) S. M. Nestor et al.   BRAIN

Progressive Encephalopathy in a Child with Cerebral Folate Deficiency Syndrome

(2008) Joshua L. Bonkowsky et al.   JOURNAL OF CHILD NEUROLOGY

MITOCHONDRIAL DISEASES ASSOCIATED WITH CEREBRAL FOLATE DEFICIENCY

(2008) A. Garcia-Cazorla et al.   NEUROLOGY