Folate Related Pathway Gene Analysis Reveals a Novel Metabolic Variant Associated with Alzheimer’s Disease with a Change in Metabolic Profile

Head injury and 25‐year risk of dementia

(2021) Andrea L. C. Schneider et al.   Alzheimers & Dementia

Epigenetics of Alzheimer’s Disease

(2021) Matea Nikolac Perkovic et al.   Biomolecules

Genetic effect of MTHFR C677T, A1298C, and A1793G polymorphisms on the age at onset, plasma homocysteine, and white matter lesions in Alzheimer's disease in the Chinese population

(2021) Yaling Jiang et al.   Aging-US

Beyond association: successes and challenges in linking non-coding genetic variation to functional consequences that modulate Alzheimer’s disease risk

(2021) Gloriia Novikova et al.   Molecular Neurodegeneration

Precision Nutrition for Alzheimer’s Prevention in ApoE4 Carriers

(2021) Nicholas G. Norwitz et al.   Nutrients

Profound changes in cerebrospinal fluid proteome and metabolic profile are associated with congenital hydrocephalus

(2021) Alicia Requena-Jimenez et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Brain Ventricular System and Cerebrospinal Fluid Development and Function: Light at the End of the Tube

(2020) Ryann M. Fame et al.   BIOESSAYS

Glymphatic System Impairment in Alzheimer’s Disease and Idiopathic Normal Pressure Hydrocephalus

(2020) Benjamin C. Reeves et al.   TRENDS IN MOLECULAR MEDICINE

Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model

(2020) Ian F Harrison et al.   BRAIN

Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop

(2020) Padma Maruvada et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Vitamin B12, B6, or Folate and Cognitive Function in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis

(2020) Chenbo Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression

(2020) Xuanye Cao et al.   JOURNAL OF MEDICAL GENETICS

Asociación de deficiencia cerebral de folato y paraplejía espástica hereditaria

(2020) S. Duarte et al.   NEUROLOGIA

Is the glymphatic system the missing link between sleep impairments and neurological disorders? Examining the implications and uncertainties

(2020) Jennaya Christensen et al.   PROGRESS IN NEUROBIOLOGY

Epigenetics: Recent Advances and Its Role in the Treatment of Alzheimer's Disease

(2020) Xuewen Xiao et al.   Frontiers in Neurology

Pharmacoresistant Epilepsy in Childhood: Think of the Cerebral Folate Deficiency, a Treatable Disease

(2020) Sarah Mafi et al.   Brain Sciences

The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices

(2020) Oliver Cameron Reddy et al.   Brain Sciences

Nutrigenomics: lessons learned and future perspectives

(2020) Lorraine Brennan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Relationships of Cerebrospinal Fluid Alzheimer’s Disease Biomarkers and COMT, DBH, and MAOB Single Nucleotide Polymorphisms

(2019) Mirjana Babić Leko et al.   JOURNAL OF ALZHEIMERS DISEASE

Neurogenesis: A process ontogenically linked to brain cavities and their content, CSF

(2019) A. Gato et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Subarachnoid cerebrospinal fluid is essential for normal development of the cerebral cortex

(2019) Jaleel Miyan et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Alzheimer’s Disease and Parkinson’s Disease: A Nutritional Toxicology Perspective of the Impact of Oxidative Stress, Mitochondrial Dysfunction, Nutrigenomics and Environmental Chemicals

(2019) Aayushi Agnihotri et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Epidemiological pathology of Aβ deposition in the ageing brain in CFAS: addition of multiple Aβ-derived measures does not improve dementia assessment using logistic regression and machine learning approaches

(2019) S. B. Wharton et al.   Acta Neuropathologica Communications

Altered folate binding protein expression and folate delivery are associated with congenital hydrocephalus in the hydrocephalic Texas rat

(2018) Alicia Requena Jimenez et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Genetic assessment and folate receptor autoantibodies in infantile-onset cerebral folate deficiency (CFD) syndrome

(2018) V.Th. Ramaekers et al.   MOLECULAR GENETICS AND METABOLISM

Early Life Stress and Epigenetics in Late-onset Alzheimer’s Dementia: A Systematic Review

(2018) Erwin Lemche   CURRENT GENOMICS

Cerebrospinal fluid and the early brain development of autism

(2018) Mark D. Shen   Journal of Neurodevelopmental Disorders

The glymphatic pathway in neurological disorders

(2018) Martin Kaag Rasmussen et al.   LANCET NEUROLOGY

Pharmacophore-based virtual screening of catechol-o-methyltransferase (COMT) inhibitors to combat Alzheimer’s disease

(2017) Chirag N. Patel et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Folic Acid Impairs the Uptake of 5-Methyltetrahydrofolate in Human Umbilical Vascular Endothelial Cells

(2017) Desiree Smith et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Folinic acid therapy in cerebral folate deficiency: marked improvement in an adult patient

(2017) Ivan Karin et al.   JOURNAL OF NEUROLOGY

Lack of association between MTHFR A1298C variant and Alzheimer’s disease: evidence from a systematic review and cumulative meta-analysis

(2017) Shumin Liu et al.   NEUROLOGICAL RESEARCH

Head Injury as a Risk Factor for Dementia and Alzheimer’s Disease: A Systematic Review and Meta-Analysis of 32 Observational Studies

(2017) Yanjun Li et al.   PLoS One

Brain Ventricular Volume and Cerebrospinal Fluid Biomarkers of Alzheimer's Disease

(2017) Brian R. Ott et al.   JOURNAL OF ALZHEIMERS DISEASE

Posterior Ventricular Enlargement to Differentiate Dementia with Lewy Bodies from Alzheimer’s Disease

(2016) Byoung Seok Ye et al.   JOURNAL OF ALZHEIMERS DISEASE

Neonatal hydrocephalus is a result of a block in folate handling and metabolism involving 10-formyltetrahydrofolate dehydrogenase

(2016) Naila Naz et al.   JOURNAL OF NEUROCHEMISTRY

Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease

(2016) Weiguo Peng et al.   NEUROBIOLOGY OF DISEASE

Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups

(2016) Richard E. Frye et al.   Frontiers in Neuroscience

The MTHFR C677T polymorphism contributes to increased risk of Alzheimer’s Disease: Evidence based on 40 case-control studies

(2015) Qiliu Peng et al.   NEUROSCIENCE LETTERS

Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury

(2014) Jeffrey J. Iliff et al.   JOURNAL OF NEUROSCIENCE

Folinic acid treatment for schizophrenia associated with folate receptor autoantibodies

(2014) V.T. Ramaekers et al.   MOLECULAR GENETICS AND METABOLISM

Early brain enlargement and elevated extra-axial fluid in infants who develop autism spectrum disorder

(2013) Mark D. Shen et al.   BRAIN

Clinical recognition and aspects of the cerebral folate deficiency syndromes

(2013) Vincent Ramaekers et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Folic acid supplementation does not reduce intracellular homocysteine, and may disturb intracellular one-carbon metabolism

(2013) Desirée E.C. Smith et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Autism Spectrum Disorder Is Associated with Ventricular Enlargement in a Low Birth Weight Population

(2013) Tammy Z. Movsas et al.   JOURNAL OF PEDIATRICS

A new form of cerebral folate deficiency with severe self-injurious behaviour

(2012) V Leuzzi et al.   ACTA PAEDIATRICA

Adult-Onset Cerebral Folate Deficiency

(2012) Zsila Sadighi et al.   ARCHIVES OF NEUROLOGY

Molecular characterization of folate receptor 1 mutations delineates cerebral folate transport deficiency

(2012) M. Grapp et al.   BRAIN

Genetic causes of cerebral folate deficiency: clinical, biochemical and therapeutic aspects

(2012) Mercedes Serrano et al.   DRUG DISCOVERY TODAY

Folate and Alzheimer: when time matters

(2012) Margareta Hinterberger et al.   JOURNAL OF NEURAL TRANSMISSION

Cerebral folate receptor autoantibodies in autism spectrum disorder

(2012) R E Frye et al.   MOLECULAR PSYCHIATRY

Role of folate receptor autoantibodies in infantile autism

(2012) V T Ramaekers et al.   MOLECULAR PSYCHIATRY

Dihydrofolate Reductase Deficiency Due to a Homozygous DHFR Mutation Causes Megaloblastic Anemia and Cerebral Folate Deficiency Leading to Severe Neurologic Disease

(2011) Holger Cario et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mechanisms of Membrane Transport of Folates into Cells and Across Epithelia

(2011) Rongbao Zhao et al.   Annual Review of Nutrition

Correlations between ventricular enlargement and gray and white matter volumes of cortex, thalamus, striatum, and internal capsule in schizophrenia

(2011) Guillermo Horga et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Cerebral Folate Deficiency Presenting as Adolescent Catatonic Schizophrenia: A Case Report

(2010) Albert Ho et al.   JOURNAL OF CHILD NEUROLOGY

Association analysis of CβS 844ins68 and MTHFD1 G1958A polymorphisms with Alzheimer’s disease in Chinese

(2010) Xiu-Hua Bi et al.   JOURNAL OF NEURAL TRANSMISSION

Folate Receptor Alpha Defect Causes Cerebral Folate Transport Deficiency: A Treatable Neurodegenerative Disorder Associated with Disturbed Myelin Metabolism

(2009) Robert Steinfeld et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Addressing a Folate Imbalance in Fetal Cerebrospinal Fluid Can Decrease the Incidence of Congenital Hydrocephalus

(2009) Sarah Cains et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cerebral folate deficiency and CNS inflammatory markers in Alpers disease

(2009) Oswald Hasselmann et al.   MOLECULAR GENETICS AND METABOLISM

Mapping correlations between ventricular expansion and CSF amyloid and tau biomarkers in 240 subjects with Alzheimer's disease, mild cognitive impairment and elderly controls

(2009) Yi-Yu Chou et al.   NEUROIMAGE

Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database

(2008) S. M. Nestor et al.   BRAIN

Progressive Encephalopathy in a Child with Cerebral Folate Deficiency Syndrome

(2008) Joshua L. Bonkowsky et al.   JOURNAL OF CHILD NEUROLOGY