Genome-wide profiling of dysregulated piRNAs and their target genes implicated in oncogenicity of tongue squamous cell carcinoma

HIWI2 induces G2/M cell cycle arrest and apoptosis in human fibrosarcoma via the ROS/DNA damage/p53 axis

(2022) Basudeb Das et al.   LIFE SCIENCES

Atorvastatin Enhances the Efficacy of Immune Checkpoint Therapy and Suppresses the Cellular and Extracellular Vesicle PD-L1

(2022) Eun-Ji Choe et al.   Pharmaceutics

Emerging roles of PIWI-interacting RNAs (piRNAs) and PIWI proteins in head and neck cancer and their potential clinical implications

(2022) Trisha Chattopadhyay et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

HMG-CoA Reductase Inhibitor Statins Activate the Transcriptional Activity of p53 by Regulating the Expression of TAZ

(2022) Chiharu Miyajima et al.   Pharmaceuticals

piRNA-823 Is a Unique Potential Diagnostic Non-Invasive Biomarker in Colorectal Cancer Patients

(2021) Norhan A. Sabbah et al.   Genes

piRNA-823 Is Involved in Cancer Stem Cell Regulation Through Altering DNA Methylation in Association With Luminal Breast Cancer

(2021) Xin Ding et al.   Frontiers in Cell and Developmental Biology

HYAL4-V1/Chondroitinase (Chase) Drives Gemcitabine Resistance and Predicts Chemotherapy Failure in Patients with Bladder Cancer

(2021) Sarrah L. Hasanali et al.   CLINICAL CANCER RESEARCH

Squalene synthase predicts poor prognosis in stage I‐III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression

(2021) Huihong Jiang et al.   CANCER SCIENCE

miR-197-5p increases Doxorubicin-mediated anticancer cytotoxicity of HT1080 fibrosarcoma cells by decreasing drug efflux

(2021) Neha Jain et al.   DNA REPAIR

Non‐coding RNAs and their cross‐talks impacting reproductive health of women

(2021) Neha Jain et al.   Wiley Interdisciplinary Reviews-RNA

piR-39980 mediates doxorubicin resistance in fibrosarcoma by regulating drug accumulation and DNA repair

(2021) Basudeb Das et al.   Communications Biology

A Novel Splice Variant of HYAL-4 Drives Malignant Transformation and Predicts Outcome in Bladder Cancer Patients.

(2020) Vinata B. Lokeshwar et al.   CLINICAL CANCER RESEARCH

Restoration of microRNA‐197 expression suppresses oncogenicity in fibrosarcoma through negative regulation of RAN

(2020) Neha Jain et al.   IUBMB LIFE

Targeting glioma-initiating cells via the tyrosine metabolic pathway

(2020) Daisuke Yamashita et al.   JOURNAL OF NEUROSURGERY

Low-density lipoprotein cholesterol lowering treatment: the current approach

(2020) Irina Crismaru et al.   Lipids in Health and Disease

Anti-Proliferative Effect of Statins Is Mediated by DNMT1 Inhibition and p21 Expression in OSCC Cells

(2020) Rachmad Anres Dongoran et al.   Cancers

Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway

(2020) Yi-Fang Yang et al.   Oncogenesis

Roles of Farnesyl-Diphosphate Farnesyltransferase 1 in Tumour and Tumour Microenvironments

(2020) Nguyen Thi Ha et al.   Cells

Cholesterol Metabolism: A Potential Therapeutic Target in Glioblastoma

(2019) Fahim Ahmad et al.   Cancers

miR‐197‐5p inhibits sarcomagenesis and induces cellular senescence via repression of KIAA0101

(2019) Neha Jain et al.   MOLECULAR CARCINOGENESIS

Expression of PIWIL2 in oral cancer and leukoplakia: Prognostic implications and insights from tumors

(2019) Shan Wang et al.   Cancer Biomarkers

PIWI‐interacting RNA 39980 promotes tumor progression and reduces drug sensitivity in neuroblastoma cells

(2019) Jyoti Roy et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The emerging role of the piRNA/piwi complex in cancer

(2019) Yongmei Liu et al.   Molecular Cancer

O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth

(2019) Jay Prakash Singh et al.   ONCOGENE

The Prognosis Value of PIWIL1 and PIWIL2 Expression in Pancreatic Cancer

(2019) Weiyao Li et al.   Journal of Clinical Medicine

piR‐39980 promotes cell proliferation, migration and invasion, and inhibits apoptosis via repression of SERPINB1 in human osteosarcoma

(2019) Basudeb Das et al.   BIOLOGY OF THE CELL

Domain-functional analyses of PIWIL1 and PABPC1 indicate their synergistic roles in protein translation via 3΄-UTRs of meiotic mRNAs†

(2018) Yaoyao Wu et al.   BIOLOGY OF REPRODUCTION

Investigating piwi-interacting RNA regulome in human neuroblastoma

(2018) Jyoti Roy et al.   GENES CHROMOSOMES & CANCER

Deciphering synergistic regulatory networks of microRNAs in hESCs and fibroblasts

(2018) Mousumi Sahu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo

(2018) Jie Zhang et al.   JOURNAL OF LIPID RESEARCH

miRNA-mediated ‘tug-of-war’ model reveals ceRNA propensity of genes in cancers

(2018) Arpit Chandan Swain et al.   Molecular Oncology

Screening for long noncoding RNAs associated with oral squamous cell carcinoma reveals the potentially oncogenic actions of DLEU1

(2018) Koyo Nishiyama et al.   Cell Death & Disease

Exonuclease Domain-Containing 1 Enhances MIWI2 piRNA Biogenesis via Its Interaction with TDRD12

(2018) Radha Raman Pandey et al.   Cell Reports

Tumor suppressive activity of PIWI-interacting RNA in human fibrosarcoma mediated through repression of RRM2

(2018) Basudeb Das et al.   MOLECULAR CARCINOGENESIS

piRNA-8041 is downregulated in human glioblastoma and suppresses tumor growth in vitro and in vivo

(2018) Daniel I. Jacobs et al.   Oncotarget

miR-429 inhibits metastasis by targeting KIAA0101 in Soft Tissue Sarcoma

(2017) Devyani Samantarrai et al.   EXPERIMENTAL CELL RESEARCH

Small RNA sequencing revealed dysregulated piRNAs in Alzheimer's disease and their probable role in pathogenesis

(2017) Jyoti Roy et al.   Molecular BioSystems

Two modes of targeting transposable elements by piRNA pathway in human testis

(2017) Ildar Gainetdinov et al.   RNA

3′ UTR G-quadruplexes regulate miRNA binding

(2017) Samuel Rouleau et al.   RNA

Expression Levels of PIWI-interacting RNA, piR-823, Are Deregulated in Tumor Tissue, Blood Serum and Urine of Patients with Renal Cell Carcinoma

(2016) ROBERT ILIEV et al.   ANTICANCER RESEARCH

Expression Levels of MMP9 and PIWIL2 in Prostate Cancer: a Case-Control Study

(2016) Negar Pouyanfar et al.   Clinical Laboratory

Piwi-interacting RNAs in cancer: emerging functions and clinical utility

(2016) Kevin W. Ng et al.   Molecular Cancer

Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches

(2016) Julia Beermann et al.   PHYSIOLOGICAL REVIEWS

PIWI-Interacting RNA: Its Biogenesis and Functions

(2015) Yuka W. Iwasaki et al.   Annual Review of Biochemistry

Noncoding RNAs in breast cancer

(2015) Pang-Kuo Lo et al.   Briefings in Functional Genomics

piRNA involvement in genome stability and human cancer

(2015) Miguel Moyano et al.   Journal of Hematology & Oncology

Associated ilium and femur from Koobi Fora, Kenya, and postcranial diversity in early Homo

(2015) Carol V. Ward et al.   JOURNAL OF HUMAN EVOLUTION

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

The role of piRNA and its potential clinical implications in cancer

(2015) Carolina Baraúna Assumpção et al.   Epigenomics

Unraveling novel TF-miRNA regulatory crosstalk in metastasis of Soft Tissue Sarcoma

(2015) Devyani Samantarrai et al.   Scientific Reports

Squalene Synthase Induces Tumor Necrosis Factor Receptor 1 Enrichment in Lipid Rafts to Promote Lung Cancer Metastasis

(2014) Yi-Fang Yang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

piRNA-823 contributes to tumorigenesis by regulating de novo DNA methylation and angiogenesis in multiple myeloma

(2014) H Yan et al.   LEUKEMIA

PIWI proteins and PIWI-interacting RNAs in the soma

(2014) Robert J. Ross et al.   NATURE

Non-coding RNAs and gastric cancer

(2014) Pei-Fei Li   WORLD JOURNAL OF GASTROENTEROLOGY

Ketone body utilization drives tumor growth and metastasis

(2012) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

Piwil2 modulates the proliferation and metastasis of colon cancer via regulation of matrix metallopeptidase 9 transcriptional activity

(2012) Dawei Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

O-Linked β-N-Acetylglucosaminylation (O-GlcNAcylation) in Primary and Metastatic Colorectal Cancer Clones and Effect ofN-Acetyl-β-d-glucosaminidase Silencing on Cell Phenotype and Transcriptome

(2012) Galit Yehezkel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Role of squalene synthase in prostate cancer risk and the biological aggressiveness of human prostate cancer

(2012) Y Fukuma et al.   PROSTATE CANCER AND PROSTATIC DISEASES

FTSite: high accuracy detection of ligand binding sites on unbound protein structures

(2011) Chi-Ho Ngan et al.   BIOINFORMATICS

FLASH: fast length adjustment of short reads to improve genome assemblies

(2011) T. Magoc et al.   BIOINFORMATICS

piR-823, a novel non-coding small RNA, demonstrates in vitro and in vivo tumor suppressive activity in human gastric cancer cells

(2011) Jia Cheng et al.   CANCER LETTERS

Non-coding RNAs as regulators of gene expression and epigenetics

(2011) M. U. Kaikkonen et al.   CARDIOVASCULAR RESEARCH

A novel organelle, the piNG-body, in the nuage of Drosophila male germ cells is associated with piRNA-mediated gene silencing

(2011) Mikhail V. Kibanov et al.   MOLECULAR BIOLOGY OF THE CELL

PIWI-interacting small RNAs: the vanguard of genome defence

(2011) Mikiko C. Siomi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SwissDock, a protein-small molecule docking web service based on EADock DSS

(2011) A. Grosdidier et al.   NUCLEIC ACIDS RESEARCH

Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma

(2010) Li Fu et al.   HEPATOLOGY

Ligand docking and binding site analysis with PyMOL and Autodock/Vina

(2010) Daniel Seeliger et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

A Broadly Conserved Pathway Generates 3′UTR-Directed Primary piRNAs

(2009) Nicolas Robine et al.   CURRENT BIOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY