Melatonin ameliorates imidacloprid-induced intestinal injury by negatively regulating the PGN/P38MAPK pathway in the common carp (Cyprinus carpio)

Ginsenoside Rg1 Mitigates Porcine Intestinal Tight Junction Disruptions Induced by LPS through the p38 MAPK/NLRP3 Inflammasome Pathway

(2022) Jian Kang et al.   Toxics

Atrazine exposure induces necroptosis through the P450/ROS pathway and causes inflammation in the gill of common carp (Cyprinus carpio L.)

(2022) Tong Xu et al.   FISH & SHELLFISH IMMUNOLOGY

Paraquat induces apoptosis, programmed necrosis, and immune dysfunction in CIK cells via the PTEN/PI3K/AKT axis

(2022) Xu Shi et al.   FISH & SHELLFISH IMMUNOLOGY

Melatonin alleviates lead-induced intestinal epithelial cell pyroptosis in the common carps (Cyprinus carpio) via miR-17-5p/TXNIP axis

(2022) Zhiying Miao et al.   FISH & SHELLFISH IMMUNOLOGY

Senolytic combination of Dasatinib and Quercetin alleviates intestinal senescence and inflammation and modulates the gut microbiome in aged mice

(2021) Tatiana Dandolini Saccon et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Mechanisms of deoxynivalenol-induced endocytosis and degradation of tight junction proteins in jejunal IPEC-J2 cells involve selective activation of the MAPK pathways

(2021) Enkai Li et al.   ARCHIVES OF TOXICOLOGY

Potential Environmental Health Risk Analysis of Neonicotinoids and a Synergist

(2021) Liwei Xu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm

(2021) Ping Gao et al.   Redox Biology

Protective effects of glutamine against soy saponins-induced enteritis, tight junction disruption, oxidative damage and autophagy in the intestine of Scophthalmus maximus L

(2021) Min Gu et al.   FISH & SHELLFISH IMMUNOLOGY

Imidacloprid increases intestinal permeability by disrupting tight junctions

(2021) Guo-Ping Zhao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Quercetin antagonizes imidacloprid-induced mitochondrial apoptosis through PTEN/PI3K/AKT in grass carp hepatocytes

(2021) Zhiruo Miao et al.   ENVIRONMENTAL POLLUTION

Exposure to imidacloprid induce oxidative stress, mitochondrial dysfunction, inflammation, apoptosis and mitophagy via NF-kappaB/JNK pathway in grass carp hepatocytes

(2021) Zhiruo Miao et al.   FISH & SHELLFISH IMMUNOLOGY

The functionality of probiotics in aquaculture: An overview

(2021) Mohamed T. El-Saadony et al.   FISH & SHELLFISH IMMUNOLOGY

Dysbiosis-Induced Secondary Bile Acid Deficiency Promotes Intestinal Inflammation

(2020) Sidhartha R. Sinha et al.   Cell Host & Microbe

Protective effect of caffeic acid phenethyl ester against imidacloprid-induced hepatotoxicity by attenuating oxidative stress, endoplasmic reticulum stress, inflammation and apoptosis

(2020) Bo Shao et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Bacterial Peptidoglycan as a Driver of Chronic Brain Inflammation

(2020) Jon D. Laman et al.   TRENDS IN MOLECULAR MEDICINE

Microbiota Metabolites in Health and Disease

(2020) Justin L. McCarville et al.   Annual Review of Immunology

Evaluation of Microbiome-Host Relationships in the Zebrafish Gastrointestinal System Reveals Adaptive Immunity Is a Target of Bis(2-ethylhexyl) Phthalate (DEHP) Exposure

(2020) Ondrej Adamovsky et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Gut microbiota and cardiovascular disease: opportunities and challenges

(2020) Negin Kazemian et al.   Microbiome

Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein

(2020) Hui-wen Xiao et al.   Microbiome

Neonicotinoids caused oxidative stress and DNA damage in juvenile Chinese rare minnows (Gobiocypris rarus)

(2020) Xue Tian et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion

(2020) Bo Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effects of imidacloprid on the oxidative stress, detoxification and gut microbiota of Chinese mitten crab, Eriocheir sinensis

(2020) Yuhang Hong et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Melatonin inhibits reproductive activity through changes of serotonergic activity in the brain of freshwater catfish (Mystus cavasius)

(2020) Muhammad Badruzzaman et al.   AQUACULTURE

Ecological risks of imidacloprid to aquatic species in the Netherlands: Measured and estimated concentrations compared to species sensitivity distributions

(2020) N.W. Thunnissen et al.   CHEMOSPHERE

Dietary choline deficiency aggravated the intestinal apoptosis in association with the MAPK signalling pathways of juvenile grass carp (Ctenopharyngodon idella)

(2020) Zehong Yuan et al.   AQUACULTURE

Neonicotinoids in the agroecosystem: In-field long-term assessment on honeybee colony strength and microbiome

(2020) D. Alberoni et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A nationwide study of occurrence and exposure assessment of neonicotinoid insecticides and their metabolites in drinking water of China

(2020) Gaga Mahai et al.   WATER RESEARCH

Effects of low-level imidacloprid oral exposure on cholinesterase activity, oxidative stress responses, and primary DNA damage in the blood and brain of male Wistar rats

(2020) Anja Katić et al.   CHEMICO-BIOLOGICAL INTERACTIONS

A novel, efficient and sustainable magnetic sludge biochar modified by graphene oxide for environmental concentration imidacloprid removal

(2020) Yongfei Ma et al.   JOURNAL OF HAZARDOUS MATERIALS

QingBai decoction regulates intestinal permeability of dextran sulphate sodium-induced colitis through the modulation of notch and NF-κB signalling

(2019) Jun-Chao Lin et al.   CELL PROLIFERATION

Interleukin‐21 enhances Toll‐like receptor 2/4‐mediated cytokine production via phosphorylation in the STAT3, Akt and p38 MAPK signalling pathways in human monocytic THP‐1 cells

(2019) Leilei Jian et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Gut microbiota: An underestimated and unintended recipient for pesticide-induced toxicity

(2019) Xianling Yuan et al.   CHEMOSPHERE

Melatonin reduces inflammatory response in human intestinal epithelial cells stimulated by interleukin‐1β

(2019) Giuseppe Mannino et al.   JOURNAL OF PINEAL RESEARCH

Inhibition of SERPINA3N‐dependent neuroinflammation is essential for melatonin to ameliorate trimethyltin chloride–induced neurotoxicity

(2019) Yu Xi et al.   JOURNAL OF PINEAL RESEARCH

Changes in intestinal microflora in digestive tract diseases during pregnancy

(2019) Min Jin et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Identification of signal pathways for immunotoxicity in the spleen of common carp exposed to chlorpyrifos

(2019) Houjuan Xing et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Bees and pesticide regulation: Lessons from the neonicotinoid experience

(2019) Fabio Sgolastra et al.   BIOLOGICAL CONSERVATION

Melatonin enhances mitochondrial biogenesis and protects against rotenone‐induced mitochondrial deficiency in early porcine embryos

(2019) Ying‐Jie Niu et al.   JOURNAL OF PINEAL RESEARCH

DNA damage and oxidative stress induced by imidacloprid exposure in different tissues of the Neotropical fish Prochilodus lineatus

(2018) Carlos Eduardo Delfino Vieira et al.   CHEMOSPHERE

Chronic brain toxicity response of juvenile Chinese rare minnows ( Gobiocypris rarus ) to the neonicotinoid insecticides imidacloprid and nitenpyram

(2018) Xue Tian et al.   CHEMOSPHERE

Environmental Risks and Challenges Associated with Neonicotinoid Insecticides

(2018) Michelle L. Hladik et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

In Inflamed Intestinal Tissues and Epithelial Cells, Interleukin 22 Signaling Increases Expression of H19 Long Noncoding RNA, Which Promotes Mucosal Regeneration

(2018) Hua Geng et al.   GASTROENTEROLOGY

Melatonin improves insulin resistance and hepatic steatosis through attenuation of alpha-2-HS-glycoprotein

(2018) Jee-In Heo et al.   JOURNAL OF PINEAL RESEARCH

Melatonin protects embryonic development and maintains sleep/wake behaviors from the deleterious effects of fluorene-9-bisphenol in zebrafish (Danio rerio )

(2018) Mi Ping et al.   JOURNAL OF PINEAL RESEARCH

Probiotic Lactobacillus plantarum Promotes Intestinal Barrier Function by Strengthening the Epithelium and Modulating Gut Microbiota

(2018) Jing Wang et al.   Frontiers in Microbiology

Dose-related impacts of imidacloprid oral intoxication on brain and liver of rock pigeon (Columba livia domestica), residues analysis in different organs

(2018) Ehsan H. Abu Zeid et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Imidacloprid Impacts on Neurobehavioral Performance, Oxidative Stress, and Apoptotic Events in the Brain of Adolescent and Adult Rats

(2018) Yasmina M. Abd-Elhakim et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Intestinal microbiome and its potential functions in bighead carp (Aristichthys nobilis) under different feeding strategies

(2018) Xuemei Li et al.   PeerJ

The protective effects of melatonin on oxidative damage and the immune system of the Chinese mitten crab (Eriocheir sinensis) exposed to deltamethrin

(2018) Cong Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Glutamate attenuates lipopolysaccharide-induced oxidative damage and mRNA expression changes of tight junction and defensin proteins, inflammatory and apoptosis response signaling molecules in the intestine of fish

(2017) Jun Jiang et al.   FISH & SHELLFISH IMMUNOLOGY

Mechanisms underlying melatonin-mediated prevention of fenvalerate-induced behavioral and oxidative toxicity in zebrafish

(2017) Jingjing Han et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Gut microbiota dysbiosis contributes to the development of hypertension

(2017) Jing Li et al.   Microbiome

Neonicotinoid-induced pathogen susceptibility is mitigated by Lactobacillus plantarum immune stimulation in a Drosophila melanogaster model

(2017) Brendan A. Daisley et al.   Scientific Reports

Evidence for indirect effects of pesticide seed treatments on weed seed banks in maize and soybean

(2016) Richard G. Smith et al.   AGRICULTURE ECOSYSTEMS & ENVIRONMENT

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

Imidacloprid Promotes High Fat Diet-Induced Adiposity and Insulin Resistance in Male C57BL/6J Mice

(2016) Quancai Sun et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Human Intestinal Barrier Function in Health and Disease

(2016) Julia König et al.   Clinical and Translational Gastroenterology

Neonicotinoid contamination of global surface waters and associated risk to aquatic invertebrates: A review

(2015) Christy A. Morrissey et al.   ENVIRONMENT INTERNATIONAL

Role of serum toll-like receptors 2 and 4 in non-alcoholic steatohepatitis and liver fibrosis

(2015) Mustafa Cengiz et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The global status of insect resistance to neonicotinoid insecticides

(2015) Chris Bass et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Dismicrobism in inflammatory bowel disease and colorectal cancer: Changes in response of colocytes

(2015) Giovanni Tomasello   WORLD JOURNAL OF GASTROENTEROLOGY

Immunological and histological effects of exposure to imidacloprid insecticide in male albino rats

(2014) Mohamed Mohany   African Journal of Pharmacy and Pharmacology

Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1-dependent mechanism during ischemic-stroke in mice

(2014) Yang Yang et al.   JOURNAL OF PINEAL RESEARCH

Biogeography and individuality shape function in the human skin metagenome

(2014) Julia Oh et al.   NATURE

Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease

(2014) Kouichi Miura   WORLD JOURNAL OF GASTROENTEROLOGY

Immune System Stimulation by Probiotic Microorganisms

(2013) Rabia Ashraf et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Factors influencing the grass carp gut microbiome and its effect on metabolism

(2013) Jiajia Ni et al.   FEMS MICROBIOLOGY ECOLOGY

Pattern recognition receptor-initiated innate antiviral response in mouse adipose cells

(2013) Lili Yu et al.   IMMUNOLOGY AND CELL BIOLOGY

The Gut Barrier

(2012) Franco Scaldaferri et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Intestinal barrier function in health and gastrointestinal disease

(2012) M. Camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

In vitro genotoxicity evaluation of acetamiprid in CaCo-2 cells using the micronucleus, comet and γH2AX foci assays

(2012) Tolga Çavaş et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Interactive metagenomic visualization in a Web browser

(2011) Brian D Ondov et al.   BMC BIOINFORMATICS

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY