Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway

FNDC5/irisin reduces ferroptosis and improves mitochondrial dysfunction in hypoxic cardiomyocytes by Nrf2/HO‐1 axis

(2022) Guangying Cao et al.   CELL BIOLOGY INTERNATIONAL

The Keap1-Nrf2 System: A Mediator between Oxidative Stress and Aging

(2021) Chao Yu et al.   Oxidative Medicine and Cellular Longevity

Mouse models of sarcopenia: classification and evaluation

(2021) Wen‐qing Xie et al.   Journal of Cachexia Sarcopenia and Muscle

Fibroblasts: Origins, definitions, and functions in health and disease

(2021) Maksim V. Plikus et al.   CELL

Role of PI3K/Akt signaling pathway in cardiac fibrosis

(2021) Wuming Qin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Redox metabolism: ROS as specific molecular regulators of cell signaling and function

(2021) Claudia Lennicke et al.   MOLECULAR CELL

Backstage players of fibrosis: NOX4, mTOR, HDAC, and S1P; companions of TGF-β

(2021) Alexis Paulina Jiménez-Uribe et al.   CELLULAR SIGNALLING

Skeletal muscle in health and disease

(2020) Jennifer Morgan et al.   Disease Models & Mechanisms

Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment

(2020) Liang-Kung Chen et al.   Journal of the American Medical Directors Association

Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles

(2020) Guo‐Kai Shang et al.   Journal of Cachexia Sarcopenia and Muscle

Irisin prevents dexamethasone-induced atrophy in C2C12 myotubes

(2020) Jae Seung Chang et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Identification of irisin as a therapeutic agent that inhibits oxidative stress and fibrosis in a murine model of chronic pancreatitis

(2020) Yifan Ren et al.   BIOMEDICINE & PHARMACOTHERAPY

Astaxanthin Protects Retinal Photoreceptor Cells against High Glucose-Induced Oxidative Stress by Induction of Antioxidant Enzymes via the PI3K/Akt/Nrf2 Pathway

(2020) Tso-Ting Lai et al.   Antioxidants

The correlation of IRE1α oxidation with Nox4 activation in aging-associated vascular dysfunction

(2020) Hwa-Young Lee et al.   Redox Biology

Irisin exerts a therapeutic effect against myocardial infarction via promoting angiogenesis

(2019) Qiao Liao et al.   ACTA PHARMACOLOGICA SINICA

Irisin attenuates angiotensin II-induced cardiac fibrosis via Nrf2 mediated inhibition of ROS/ TGFβ1/Smad2/3 signaling axis

(2019) Rui-Rui Chen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Role of Transforming Growth Factor-β in Skeletal Muscle Fibrosis: A Review

(2019) Ahmed Ismaeel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

d-Galactose-induced accelerated aging model: an overview

(2019) Khairunnuur Fairuz Azman et al.   BIOGERONTOLOGY

Skeletal muscle: A review of molecular structure and function, in health and disease

(2019) Kavitha Mukund et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

TGF-β Signaling in Cellular Senescence and Aging-Related Pathology

(2019) Kana Tominaga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Resveratrol Attenuates Oxidative Stress-Induced Intestinal Barrier Injury through PI3K/Akt-Mediated Nrf2 Signaling Pathway

(2019) Yu Zhuang et al.   Oxidative Medicine and Cellular Longevity

Resistance training prevents muscle fibrosis and atrophy via down-regulation of C1q-induced Wnt signaling in senescent mice

(2018) Naoki Horii et al.   FASEB JOURNAL

Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications

(2018) Ralf Weiskirchen et al.   MOLECULAR ASPECTS OF MEDICINE

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

(2018) Masayuki Yamamoto et al.   PHYSIOLOGICAL REVIEWS

OUP accepted manuscript

(2018)   AGE AND AGEING

Skeletal muscle fibrosis: an overview

(2018) Mohamed A. A. Mahdy   CELL AND TISSUE RESEARCH

Myokine mediated muscle-kidney crosstalk suppresses metabolic reprogramming and fibrosis in damaged kidneys

(2017) Hui Peng et al.   Nature Communications

Skeletal muscle performance and ageing

(2017) Michael Tieland et al.   Journal of Cachexia Sarcopenia and Muscle

The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways

(2017) Xubo Chen et al.   Redox Biology

Redox mechanisms in age-related lung fibrosis

(2016) Ashish Kurundkar et al.   Redox Biology

Resistance exercise training increases the expression of irisin concomitant with improvement of muscle function in aging mice and humans

(2015) Hee-jae Kim et al.   EXPERIMENTAL GERONTOLOGY

Redox-fibrosis: Impact of TGFβ1 on ROS generators, mediators and functional consequences

(2015) Kati Richter et al.   Redox Biology

Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance

(2014) L. Hecker et al.   Science Translational Medicine

Nox4 modulates collagen production stimulated by transforming growth factor β1 in vivo and in vitro

(2012) Elsa C. Chan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise

(2012) Joo Young Huh et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

(2011) Alison C. Brewer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Structure and function of the skeletal muscle extracellular matrix

(2011) Allison R. Gillies et al.   MUSCLE & NERVE

Aberrant repair and fibrosis development in skeletal muscle

(2011) Christopher J Mann et al.   Skeletal Muscle

NAD(P)H Oxidase Mediates TGF- 1-Induced Activation of Kidney Myofibroblasts

(2009) C. D. Bondi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY